SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6apb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOJ_C_FRDC305_1 (POL POLYPROTEIN PEPTIDE INHIBITOR)	6apb	ADI-14359 FAB LIGHT CHAIN (Homo sapiens)	4 / 5	LEU L 179 GLY L 128 PRO L 120 VAL L 132	None	0.87A	2aojA-6apbL: undetectable	2aojA-6apbL: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VAV_F_CSCF1383_1 (ACETYL-COA--DEACETYL CEPHALOSPORIN C ACETYLTRANSFERASE)	6apb	ADI-14359 FAB LIGHT CHAIN (Homo sapiens)	5 / 12	THR L 102 THR L 85 TYR L 140 GLN L 166 VAL L 19	None	1.50A	2vavF-6apbL: 0.0	2vavF-6apbL: 10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VAX_B_CSCB1384_1 (ACETYL-COA--DEACETYL CEPHALOSPORIN C ACETYLTRANSFERASE)	6apb	ADI-14359 FAB LIGHT CHAIN (Homo sapiens)	5 / 12	THR L 102 THR L 85 TYR L 140 GLN L 166 VAL L 19	None	1.47A	2vaxB-6apbL: undetectable	2vaxB-6apbL: 10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VAX_I_CSCI1384_1 (ACETYL-COA--DEACETYL CEPHALOSPORIN C ACETYLTRANSFERASE)	6apb	ADI-14359 FAB LIGHT CHAIN (Homo sapiens)	5 / 12	THR L 102 THR L 85 TYR L 140 GLN L 166 VAL L 19	None	1.47A	2vaxI-6apbL: undetectable	2vaxI-6apbL: 10.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AOJ_C_FRDC305_1","POL POLYPROTEIN;PEPTIDE INHIBITOR","6apb","ADI-14359 FAB LIGHT CHAIN","Homo sapiens",4,"LEU L 179;GLY L 128;PRO L 120;VAL L 132","None","0.87A","2aojA-6apbL:undetectable","2aojA-6apbL:19.09"],["2VAV_F_CSCF1383_1","ACETYL-COA--DEACETYLCEPHALOSPORIN C ACETYLTRANSFERASE","6apb","ADI-14359 FAB LIGHT CHAIN","Homo sapiens",5,"THR L 102;THR L  85;TYR L 140;GLN L 166;VAL L  19","None","1.50A","2vavF-6apbL:0.0","2vavF-6apbL:10.88"],["2VAX_B_CSCB1384_1","ACETYL-COA--DEACETYLCEPHALOSPORIN C ACETYLTRANSFERASE","6apb","ADI-14359 FAB LIGHT CHAIN","Homo sapiens",5,"THR L 102;THR L  85;TYR L 140;GLN L 166;VAL L  19","None","1.47A","2vaxB-6apbL:undetectable","2vaxB-6apbL:10.88"],["2VAX_I_CSCI1384_1","ACETYL-COA--DEACETYLCEPHALOSPORIN C ACETYLTRANSFERASE","6apb","ADI-14359 FAB LIGHT CHAIN","Homo sapiens",5,"THR L 102;THR L  85;TYR L 140;GLN L 166;VAL L  19","None","1.47A","2vaxI-6apbL:undetectable","2vaxI-6apbL:10.88"]]