SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6apg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 12 GLY A 161
GLY A 122
ILE A 159
ALA A 124
SER A 192
 None
 1.17A 1ri4A-6apgA:
undetectable		 1ri4A-6apgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 12 ILE A 166
GLY A 122
GLY A 120
VAL A 186
SER A 187
 None
None
GOL  A 302 (-3.6A)
None
None
 1.04A 1sg9B-6apgA:
undetectable		 1sg9B-6apgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 10 PHE A  94
ALA A  66
LEU A  67
LEU A  27
LEU A  82
 None
 1.10A 2bxqA-6apgA:
1.6		 2bxqA-6apgA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQE_A_ADNA1002_1
(APRATAXIN AND
PNK-LIKE FACTOR)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		4 / 5 TYR A  69
SER A  68
TYR A   4
ARG A  73
 None
SO4  A 303 ( 4.3A)
None
None
 1.47A 2kqeA-6apgA:
undetectable		 2kqeA-6apgA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 11 ALA A 143
GLU A 165
VAL A 134
ILE A 166
VAL A 126
 None
 0.93A 2uxpB-6apgA:
undetectable		 2uxpB-6apgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 11 LEU A  87
ARG A 111
MET A  16
GLY A 265
HIS A 266
 None
MLI  A 301 (-3.3A)
None
None
SO4  A 303 (-3.8A)
 1.34A 3hm1B-6apgA:
undetectable		 3hm1B-6apgA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_B_T1CB392_1
(TETX2 PROTEIN)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 11 GLN A  12
ARG A 111
GLY A  10
GLY A 116
MET A 123
 None
MLI  A 301 (-3.3A)
None
None
MLI  A 301 ( 4.4A)
 1.37A 4a6nB-6apgA:
undetectable		 4a6nB-6apgA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_C_T1CC392_1
(TETX2 PROTEIN)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 11 GLN A  12
ARG A 111
GLY A  10
GLY A 116
MET A 123
 None
MLI  A 301 (-3.3A)
None
None
MLI  A 301 ( 4.4A)
 1.38A 4a6nC-6apgA:
undetectable		 4a6nC-6apgA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_A_MIYA391_1
(TETX2 PROTEIN)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 10 GLN A  12
ARG A 111
GLY A  10
GLY A 116
MET A 123
 None
MLI  A 301 (-3.3A)
None
None
MLI  A 301 ( 4.4A)
 1.37A 4a99A-6apgA:
undetectable		 4a99A-6apgA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_B_MIYB391_1
(TETX2 PROTEIN)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 11 GLN A  12
ARG A 111
GLY A  10
GLY A 116
MET A 123
 None
MLI  A 301 (-3.3A)
None
None
MLI  A 301 ( 4.4A)
 1.34A 4a99B-6apgA:
undetectable		 4a99B-6apgA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC391_1
(TETX2 PROTEIN)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 11 GLN A  12
ARG A 111
GLY A  10
GLY A 116
MET A 123
 None
MLI  A 301 (-3.3A)
None
None
MLI  A 301 ( 4.4A)
 1.34A 4a99C-6apgA:
undetectable		 4a99C-6apgA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD391_1
(TETX2 PROTEIN)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 11 GLN A  12
ARG A 111
GLY A  10
GLY A 116
MET A 123
 None
MLI  A 301 (-3.3A)
None
None
MLI  A 301 ( 4.4A)
 1.34A 4a99D-6apgA:
undetectable		 4a99D-6apgA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		4 / 7 LEU A  67
THR A  28
ILE A  39
GLY A  17
 None
None
None
SO4  A 303 (-3.3A)
 0.97A 4eq4A-6apgA:
undetectable		 4eq4A-6apgA:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 9 GLY A 265
GLY A  88
PHE A   6
SER A  91
GLY A   8
 None
 1.34A 4kqiA-6apgA:
undetectable		 4kqiA-6apgA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		4 / 5 THR A  57
THR A  54
HIS A  85
ASN A  65
 None
None
MLI  A 301 (-4.7A)
None
 1.28A 4pgfB-6apgA:
undetectable		 4pgfB-6apgA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		4 / 6 PHE A 211
GLY A 104
TYR A 209
ALA A 106
 None
 1.27A 4yshB-6apgA:
undetectable		 4yshB-6apgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 7 ARG A 111
VAL A 108
LEU A  87
SER A  86
GLU A  89
 MLI  A 301 (-3.3A)
None
None
MLI  A 301 (-3.0A)
None
 1.49A 4zphA-6apgA:
undetectable
4zphB-6apgA:
undetectable		 4zphA-6apgA:
undetectable
4zphB-6apgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		4 / 5 SER A 242
GLY A 203
GLU A 207
ARG A 193
 None
 1.11A 5cdqA-6apgA:
undetectable
5cdqB-6apgA:
undetectable
5cdqC-6apgA:
undetectable		 5cdqA-6apgA:
11.06
5cdqB-6apgA:
17.53
5cdqC-6apgA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		4 / 5 SER A 242
GLY A 203
GLU A 207
ARG A 193
 None
 1.16A 5cdqR-6apgA:
undetectable
5cdqS-6apgA:
undetectable
5cdqT-6apgA:
undetectable		 5cdqR-6apgA:
11.06
5cdqS-6apgA:
17.53
5cdqT-6apgA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 12 GLN A  58
LEU A  35
VAL A  34
TYR A 209
GLY A 104
 MLI  A 301 ( 4.6A)
None
None
None
None
 1.36A 5i8fA-6apgA:
undetectable		 5i8fA-6apgA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		4 / 8 ILE A  39
LEU A  42
LEU A  51
PRO A  59
 None
 0.84A 5u4sB-6apgA:
undetectable		 5u4sB-6apgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 6apg DISD PROTEIN
(Sorangium
cellulosum) 		5 / 12 GLN A  58
VAL A 222
GLY A  10
ALA A 125
VAL A 126
 MLI  A 301 ( 4.6A)
None
None
None
None
 1.04A 6c2mC-6apgA:
undetectable		 6c2mC-6apgA:
21.69