SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6apq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_D_ADND500_2 (ADENOSYLHOMOCYSTEINA SE)	6apq	ANTI-MARBURGVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY B (Lama glama)	4 / 5	LEU A 20 GLN A 113 THR A 112 LEU A 85	None	1.15A	3ce6D-6apqA: undetectable	3ce6D-6apqA: 12.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3QXV_A_MTXA2000_1 (ANTI-METHOTREXATE CDR1-4 GRAFT VHH)	6apq	ANTI-MARBURGVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY B (Lama glama)	6 / 12	VAL A 2 ALA A 24 ARG A 71 ASN A 73 VAL A 78 TYR A 107	None CL A 202 ( 4.0A) None None None None	1.19A	3qxvA-6apqA: 19.2	3qxvA-6apqA: 66.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	6apq	ANTI-MARBURGVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY B (Lama glama)	4 / 7	ALA A 91 THR A 90 VAL A 114 GLU A 88	None	0.82A	5ecoD-6apqA: undetectable	5ecoD-6apqA: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_B_HISB402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	6apq	ANTI-MARBURGVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY B (Lama glama)	5 / 9	VAL A 78 LEU A 34 GLY A 109 LEU A 4 GLN A 5	None	1.33A	6czmA-6apqA: undetectable 6czmB-6apqA: undetectable	6czmA-6apqA: 14.77 6czmB-6apqA: 14.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CE6_D_ADND500_2","ADENOSYLHOMOCYSTEINASE","6apq","ANTI-MARBURGVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY B","Lama glama",4,"LEU A  20;GLN A 113;THR A 112;LEU A  85","None","1.15A","3ce6D-6apqA:undetectable","3ce6D-6apqA:12.83"],["3QXV_A_MTXA2000_1","ANTI-METHOTREXATE CDR1-4 GRAFT VHH","6apq","ANTI-MARBURGVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY B","Lama glama",6,"VAL A   2;ALA A  24;ARG A  71;ASN A  73;VAL A  78;TYR A 107","None; CL A 202 ( 4.0A);None;None;None;None","1.19A","3qxvA-6apqA:19.2","3qxvA-6apqA:66.93"],["5ECO_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","6apq","ANTI-MARBURGVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY B","Lama glama",4,"ALA A  91;THR A  90;VAL A 114;GLU A  88","None","0.82A","5ecoD-6apqA:undetectable","5ecoD-6apqA:10.80"],["6CZM_B_HISB402_0","ATP PHOSPHORIBOSYLTRANSFERASE CATALYTIC SUBUNIT","6apq","ANTI-MARBURGVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY B","Lama glama",5,"VAL A  78;LEU A  34;GLY A 109;LEU A   4;GLN A   5","None","1.33A","6czmA-6apqA:undetectable;6czmB-6apqA:undetectable","6czmA-6apqA:14.77;6czmB-6apqA:14.77"]]