SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6aqf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		5 / 12 HIS A 278
ILE A  64
TYR A   9
ALA A  81
GLU A  13
 None
OLA  A1206 ( 4.0A)
None
None
None
 1.46A 1ki7A-6aqfA:
undetectable		 1ki7A-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		4 / 6 THR A  88
PHE A 242
HIS A 250
ASN A 181
 None
None
ZMA  A1201 (-3.9A)
None
 1.38A 1tt0A-6aqfA:
undetectable		 1tt0A-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		4 / 6 THR A  88
PHE A 242
HIS A 250
ASN A 181
 None
None
ZMA  A1201 (-3.9A)
None
 1.36A 1tt0B-6aqfA:
undetectable		 1tt0B-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		4 / 6 THR A  88
PHE A 242
HIS A 250
ASN A 181
 None
None
ZMA  A1201 (-3.9A)
None
 1.35A 1tt0C-6aqfA:
undetectable		 1tt0C-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		4 / 6 THR A  88
PHE A 242
HIS A 250
ASN A 181
 None
None
ZMA  A1201 (-3.9A)
None
 1.40A 1tt0D-6aqfA:
undetectable		 1tt0D-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		5 / 11 ALA A  81
PHE A  79
LEU A 137
VAL A 171
VAL A 172
 None
OLC  A1216 ( 4.6A)
None
None
None
 0.85A 1ukbA-6aqfA:
undetectable		 1ukbA-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		4 / 5 TRP A 246
PRO A 248
LEU A 244
GLY A 240
 None
CLR  A1202 (-4.1A)
None
None
 1.47A 1ya4C-6aqfA:
0.5		 1ya4C-6aqfA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A  29
VAL A  27
TRP A  32
 None
 1.12A 2xdcC-6aqfA:
undetectable
2xdcD-6aqfA:
undetectable		 2xdcC-6aqfA:
undetectable
2xdcD-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A  29
VAL A  27
TRP A  32
 None
 1.09A 2xdcE-6aqfA:
undetectable
2xdcF-6aqfA:
undetectable		 2xdcE-6aqfA:
undetectable
2xdcF-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A  29
VAL A  27
TRP A  32
 None
 1.12A 2y5mE-6aqfA:
undetectable
2y5mF-6aqfA:
undetectable		 2y5mE-6aqfA:
undetectable
2y5mF-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A  29
VAL A  27
TRP A  32
 None
 1.10A 2y6nC-6aqfA:
undetectable
2y6nD-6aqfA:
undetectable		 2y6nC-6aqfA:
undetectable
2y6nD-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A  29
VAL A  27
TRP A  32
 None
 1.11A 2y6nE-6aqfA:
undetectable
2y6nF-6aqfA:
undetectable		 2y6nE-6aqfA:
undetectable
2y6nF-6aqfA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		11 / 12 LEU A  85
PHE A 168
GLU A 169
MET A 177
TRP A 246
LEU A 249
ASN A 253
MET A 270
ILE A 274
SER A 277
HIS A 278
 None
ZMA  A1201 (-3.5A)
ZMA  A1201 (-4.1A)
None
None
ZMA  A1201 (-4.1A)
ZMA  A1201 (-3.2A)
ZMA  A1201 (-4.8A)
ZMA  A1201 (-4.8A)
None
None
 0.76A 2ydoA-6aqfA:
33.6		 2ydoA-6aqfA:
83.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		11 / 12 LEU A  85
THR A  88
PHE A 168
GLU A 169
MET A 177
TRP A 246
LEU A 249
ASN A 253
MET A 270
ILE A 274
SER A 277
 None
None
ZMA  A1201 (-3.5A)
ZMA  A1201 (-4.1A)
None
None
ZMA  A1201 (-4.1A)
ZMA  A1201 (-3.2A)
ZMA  A1201 (-4.8A)
ZMA  A1201 (-4.8A)
None
 1.09A 2ydoA-6aqfA:
33.6		 2ydoA-6aqfA:
83.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		3 / 3 CYH A 254
PHE A 257
PHE A 258
 CLR  A1203 (-4.0A)
None
None
 0.69A 3cr5X-6aqfA:
undetectable		 3cr5X-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL A 186
LEU A 187
VAL A 239
ALA A 243
LEU A 247
 None
None
None
None
CLR  A1202 ( 4.3A)
 1.02A 3ln1A-6aqfA:
undetectable		 3ln1A-6aqfA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL A 186
LEU A 187
VAL A 239
ALA A 243
LEU A 247
 None
None
None
None
CLR  A1202 ( 4.3A)
 1.02A 3ln1B-6aqfA:
undetectable		 3ln1B-6aqfA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL A 186
LEU A 187
VAL A 239
ALA A 243
LEU A 247
 None
None
None
None
CLR  A1202 ( 4.3A)
 1.02A 3ln1C-6aqfA:
undetectable		 3ln1C-6aqfA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL A 186
LEU A 187
VAL A 239
ALA A 243
LEU A 247
 None
None
None
None
CLR  A1202 ( 4.3A)
 1.02A 3ln1D-6aqfA:
undetectable		 3ln1D-6aqfA:
9.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		5 / 7 PHE A 168
LEU A 249
ASN A 253
MET A 270
ILE A 274
 ZMA  A1201 (-3.5A)
ZMA  A1201 (-4.1A)
ZMA  A1201 (-3.2A)
ZMA  A1201 (-4.8A)
ZMA  A1201 (-4.8A)
 0.69A 3rfmA-6aqfA:
37.3		 3rfmA-6aqfA:
86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		6 / 7 VAL A  84
PHE A 168
MET A 177
LEU A 249
ASN A 253
ILE A 274
 None
ZMA  A1201 (-3.5A)
None
ZMA  A1201 (-4.1A)
ZMA  A1201 (-3.2A)
ZMA  A1201 (-4.8A)
 0.62A 3rfmA-6aqfA:
37.3		 3rfmA-6aqfA:
86.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_2
(HIV-1 PROTEASE)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU A  85
ALA A  63
VAL A  55
THR A  88
VAL A  84
 None
 0.96A 3so9B-6aqfA:
undetectable		 3so9B-6aqfA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A  29
VAL A  27
TRP A  32
 None
 1.16A 3zq8A-6aqfA:
undetectable
3zq8B-6aqfA:
undetectable		 3zq8A-6aqfA:
undetectable
3zq8B-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		4 / 8 ASN A1006
GLU A1008
ASN A1013
ASP A1012
 None
 0.86A 4d33A-6aqfA:
undetectable		 4d33A-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ILE A1017
ALA A1075
GLN A1071
THR A1097
LEU A1014
 None
 1.37A 4qzuA-6aqfA:
undetectable		 4qzuA-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL A 186
ALA A  99
VAL A 239
ALA A 243
LEU A 247
 None
None
None
None
CLR  A1202 ( 4.3A)
 1.05A 5kirB-6aqfA:
undetectable		 5kirB-6aqfA:
10.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		8 / 8 LEU A  85
PHE A 168
GLU A 169
MET A 177
LEU A 249
ASN A 253
MET A 270
ILE A 274
 None
ZMA  A1201 (-3.5A)
ZMA  A1201 (-4.1A)
None
ZMA  A1201 (-4.1A)
ZMA  A1201 (-3.2A)
ZMA  A1201 (-4.8A)
ZMA  A1201 (-4.8A)
 0.28A 5mzjA-6aqfA:
50.7		 5mzjA-6aqfA:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		9 / 9 ILE A  66
VAL A  84
PHE A 168
GLU A 169
MET A 177
LEU A 249
ASN A 253
MET A 270
ILE A 274
 None
None
ZMA  A1201 (-3.5A)
ZMA  A1201 (-4.1A)
None
ZMA  A1201 (-4.1A)
ZMA  A1201 (-3.2A)
ZMA  A1201 (-4.8A)
ZMA  A1201 (-4.8A)
 0.32A 5mzpA-6aqfA:
50.9		 5mzpA-6aqfA:
98.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		4 / 4 ASN A  24
SER A  91
ALA A  49
VAL A  46
 None
 1.14A 5nm5A-6aqfA:
undetectable		 5nm5A-6aqfA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		6 / 6 ASN A  39
THR A  41
ASN A  42
ARG A 102
ILE A 292
GLU A 294
 None
 0.56A 5uigA-6aqfA:
41.1		 5uigA-6aqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9H_R_ADNR400_1
(CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		5 / 10 PHE A 168
GLU A 169
MET A 177
LEU A 249
ASN A 253
 ZMA  A1201 (-3.5A)
ZMA  A1201 (-4.1A)
None
ZMA  A1201 (-4.1A)
ZMA  A1201 (-3.2A)
 1.11A 6d9hR-6aqfA:
30.1		 6d9hR-6aqfA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9H_R_ADNR400_1
(CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		7 / 10 VAL A  84
PHE A 168
MET A 177
LEU A 249
ASN A 253
ILE A 274
HIS A 278
 None
ZMA  A1201 (-3.5A)
None
ZMA  A1201 (-4.1A)
ZMA  A1201 (-3.2A)
ZMA  A1201 (-4.8A)
None
 1.00A 6d9hR-6aqfA:
30.1		 6d9hR-6aqfA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9H_R_ADNR400_1
(CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		7 / 10 VAL A  84
THR A  88
PHE A 168
MET A 177
LEU A 249
ASN A 253
ILE A 274
 None
None
ZMA  A1201 (-3.5A)
None
ZMA  A1201 (-4.1A)
ZMA  A1201 (-3.2A)
ZMA  A1201 (-4.8A)
 1.08A 6d9hR-6aqfA:
30.1		 6d9hR-6aqfA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens) 		4 / 4 ASP A  52
SER A  90
SER A  94
ASN A 280
 None
 1.46A 6iblA-6aqfA:
25.2		 6iblA-6aqfA:
undetectable