SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6asb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P9G_A_ACTA42_0
(EAFP 2)		 6asb F-BOX/LRR-REPEAT
PROTEIN 19
(Homo
sapiens) 		3 / 3 CYH C  50
ARG C  47
CYH C  72
 ZN  C2002 (-2.2A)
None
ZN  C2002 (-2.3A)
 1.44A 1p9gA-6asbC:
undetectable		 1p9gA-6asbC:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 6asb F-BOX/LRR-REPEAT
PROTEIN 19
(Homo
sapiens) 		4 / 6 VAL C 121
LEU C  90
CYH C 145
CYH C 114
 None
None
ZN  C2004 (-2.3A)
ZN  C2004 (-2.3A)
 1.17A 5hrqB-6asbC:
undetectable
5hrqI-6asbC:
undetectable
5hrqJ-6asbC:
undetectable		 5hrqB-6asbC:
14.29
5hrqI-6asbC:
13.64
5hrqJ-6asbC:
14.29