SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6asx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4II8_A_010A210_0 (LYSOZYME C)	6asx	DNA-DIRECTED RNA POLYMERASE SUBUNIT OMEGA (Escherichia coli)	4 / 7	GLU K 68 ASP K 65 ASN K 61 ILE K 59	None	0.94A	4ii8A-6asxK: undetectable	4ii8A-6asxK: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVW_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	6asx	DNA-DIRECTED RNA POLYMERASE SUBUNIT OMEGA (Escherichia coli)	5 / 11	ALA K 27 THR K 46 ALA K 50 GLY K 33 GLY K 34	None	1.11A	4qvwY-6asxK: undetectable 4qvwZ-6asxK: undetectable	4qvwY-6asxK: 16.19 4qvwZ-6asxK: 15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZW4_A_SAMA302_1 (PUTATIVE O-METHYLTRANSFERASE YRRM)	6asx	DNA-DIRECTED RNA POLYMERASE SUBUNIT OMEGA (Escherichia coli)	4 / 6	GLU K 53 ARG K 52 ASP K 44 ASP K 36	None	1.25A	5zw4A-6asxK: undetectable	5zw4A-6asxK: undetectable