SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6at7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 10 GLY A 481
VAL A 483
ARG A 400
ILE A 463
GLY A 393
 None
 1.30A 1fohA-6at7A:
undetectable		 1fohA-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 10 GLY A 481
VAL A 483
ARG A 400
ILE A 463
GLY A 393
 None
 1.31A 1fohB-6at7A:
undetectable		 1fohB-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 10 GLY A 481
VAL A 483
ARG A 400
ILE A 463
GLY A 393
 None
 1.36A 1fohD-6at7A:
undetectable		 1fohD-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 ASP A 192
ILE A 392
PRO A 391
ILE A 361
ALA A 257
 MDO  A 190 ( 4.4A)
None
None
None
None
 1.14A 1kijB-6at7A:
undetectable		 1kijB-6at7A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 7 ARG A 363
ILE A 392
PRO A 391
GLU A 364
 None
 1.11A 1oniA-6at7A:
undetectable
1oniB-6at7A:
undetectable		 1oniA-6at7A:
undetectable
1oniB-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 6 ARG A 363
ILE A 392
PRO A 391
GLU A 364
 None
 1.16A 1oniB-6at7A:
undetectable
1oniC-6at7A:
undetectable		 1oniB-6at7A:
undetectable
1oniC-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 5 ARG A 363
ILE A 392
PRO A 391
GLU A 364
 None
 1.15A 1oniG-6at7A:
undetectable
1oniH-6at7A:
undetectable		 1oniG-6at7A:
undetectable
1oniH-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 10 GLY A 481
VAL A 483
ARG A 400
ILE A 463
GLY A 393
 None
 1.31A 1pn0A-6at7A:
undetectable		 1pn0A-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 10 GLY A 481
VAL A 483
ARG A 400
ILE A 463
GLY A 393
 None
 1.33A 1pn0B-6at7A:
undetectable		 1pn0B-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 9 VAL A 394
LEU A  22
VAL A 353
ALA A 357
SER A 360
 None
 1.28A 1pxxB-6at7A:
undetectable		 1pxxB-6at7A:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		3 / 3 LEU A 295
HIS A 290
ILE A 302
 None
 0.54A 1s9pB-6at7A:
undetectable		 1s9pB-6at7A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 MET A 410
LEU A 495
ILE A 677
MET A 686
ILE A 406
 None
 1.39A 1xotA-6at7A:
undetectable		 1xotA-6at7A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 ALA A 267
GLY A 348
GLY A 300
LEU A 354
LEU A  22
 None
 0.96A 1ya4A-6at7A:
undetectable		 1ya4A-6at7A:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 GLY A 393
THR A 188
ALA A 357
THR A 358
ALA A 485
 None
MDO  A 190 ( 4.4A)
None
None
None
 0.90A 2gluB-6at7A:
undetectable		 2gluB-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 ALA A  80
GLY A 160
TYR A 158
HIS A 377
VAL A 376
 None
 1.06A 3f8wA-6at7A:
undetectable		 3f8wA-6at7A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 7 LEU A 154
VAL A 246
LEU A 237
LEU A 173
 None
 0.73A 3g8iA-6at7A:
undetectable		 3g8iA-6at7A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 TYR A 158
ALA A  80
GLY A 160
SER A 159
HIS A 377
 None
 1.25A 3ou7C-6at7A:
undetectable		 3ou7C-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 7 VAL A 246
LEU A 124
GLN A 117
LEU A 116
 None
 0.95A 3qeoB-6at7A:
undetectable		 3qeoB-6at7A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 LEU A 181
GLY A 201
ILE A 199
ILE A 203
ALA A 209
 None
 1.14A 3uj7A-6at7A:
undetectable		 3uj7A-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 5 LEU A 255
GLY A 252
THR A 188
ILE A 463
 None
None
MDO  A 190 ( 4.4A)
None
 0.91A 3wriB-6at7A:
undetectable		 3wriB-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 7 PHE A 102
ASN A 247
GLY A 242
LEU A 124
 None
MDO  A 190 ( 3.2A)
None
None
 0.81A 4ejjD-6at7A:
undetectable		 4ejjD-6at7A:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 GLY A 481
GLY A 252
THR A 188
ASN A 478
SER A 484
 None
None
MDO  A 190 ( 4.4A)
None
None
 1.18A 4f84A-6at7A:
undetectable		 4f84A-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 10 SER A  81
ARG A  77
ALA A  74
LEU A 155
ALA A  63
 None
 1.41A 4fe1A-6at7A:
undetectable
4fe1J-6at7A:
undetectable		 4fe1A-6at7A:
7.15
4fe1J-6at7A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 8 ASP A 262
ALA A  55
SER A  59
TYR A 261
 None
 1.08A 4lv9A-6at7A:
undetectable
4lv9B-6at7A:
undetectable		 4lv9A-6at7A:
10.98
4lv9B-6at7A:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 7 TYR A 261
ASP A 262
ALA A  55
SER A  59
 None
 1.11A 4lv9A-6at7A:
undetectable
4lv9B-6at7A:
undetectable		 4lv9A-6at7A:
10.98
4lv9B-6at7A:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 VAL A 259
ILE A 392
VAL A 353
ALA A 357
SER A 360
 None
 0.80A 4m11D-6at7A:
undetectable		 4m11D-6at7A:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 6 ASN A 678
MET A 410
LEU A 495
VAL A 259
 None
 1.09A 4okbA-6at7A:
undetectable		 4okbA-6at7A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 ALA A 489
ILE A 492
LEU A 456
GLY A 407
GLN A 457
 None
 1.21A 4r38C-6at7A:
undetectable		 4r38C-6at7A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 ASN A 525
ALA A 622
VAL A 626
ALA A 631
ILE A 519
 None
 1.17A 4x1kD-6at7A:
undetectable		 4x1kD-6at7A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 11 ASN A 465
ILE A 463
THR A 188
GLY A 481
ASP A 397
 None
None
MDO  A 190 ( 4.4A)
None
None
 1.37A 4xt7A-6at7A:
undetectable		 4xt7A-6at7A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 11 THR A 390
SER A 479
GLY A 389
ASP A 192
THR A 186
 None
MDO  A 190 ( 4.8A)
MDO  A 190 ( 4.9A)
MDO  A 190 ( 4.4A)
MDO  A 190 ( 4.9A)
 1.33A 4xt7A-6at7A:
undetectable		 4xt7A-6at7A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 7 ARG A  77
VAL A  78
LEU A 155
GLU A  73
 None
 1.02A 4zphA-6at7A:
undetectable
4zphB-6at7A:
undetectable		 4zphA-6at7A:
undetectable
4zphB-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 6 PHE A 414
SER A 499
MET A 449
LEU A 273
 None
 1.47A 5dzka-6at7A:
undetectable
5dzko-6at7A:
undetectable		 5dzka-6at7A:
undetectable
5dzko-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 6 SER A 159
GLY A 248
ASN A 369
ILE A 245
 None
MDO  A 190 ( 4.0A)
None
None
 1.12A 5j4nA-6at7A:
undetectable		 5j4nA-6at7A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 MET A 147
ILE A 169
ALA A 221
ILE A 203
PRO A 179
 None
 1.30A 5mlmA-6at7A:
undetectable		 5mlmA-6at7A:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 8 ALA A 200
ILE A 165
ALA A 168
ILE A 169
 None
 0.67A 5mvmA-6at7A:
1.3
5mvmB-6at7A:
1.3		 5mvmA-6at7A:
26.19
5mvmB-6at7A:
26.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 10 ALA A 200
ILE A 165
ALA A 168
ILE A 169
ILE A 230
 None
 0.99A 5mvmD-6at7A:
undetectable
5mvmE-6at7A:
undetectable		 5mvmD-6at7A:
26.19
5mvmE-6at7A:
26.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 6 ARG A 108
THR A 110
ASP A 112
LEU A 116
 None
 0.97A 5tdzA-6at7A:
undetectable		 5tdzA-6at7A:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 6 ASN A 525
THR A 521
ILE A 554
GLU A 550
 None
 1.33A 5uigA-6at7A:
2.5		 5uigA-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		5 / 12 GLU A 652
LEU A 682
ILE A 677
TYR A 452
CYH A 670
 None
 1.39A 5vlmA-6at7A:
undetectable		 5vlmA-6at7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 6at7 PHENYLALANINE
AMMONIA-LYASE
(Sorghum
bicolor) 		4 / 6 ARG A  32
ARG A  50
ALA A 267
GLN A  36
 None
 1.08A 6b89B-6at7A:
2.7		 6b89B-6at7A:
22.83