SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6au1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 THR A 397
VAL A 357
VAL A 401
LEU A 342
ILE A 346
 None
 1.06A 1t6zB-6au1A:
undetectable		 1t6zB-6au1A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 MET A 584
ASN A 547
GLN A 564
 None
 0.86A 1xoqB-6au1A:
undetectable		 1xoqB-6au1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LEU A 381
ASN A 378
LEU A 461
LEU A 529
LEU A 443
 None
 1.25A 1zucB-6au1A:
undetectable		 1zucB-6au1A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		4 / 6 PHE A 612
VAL A 576
LEU A 548
ALA A 580
 None
 1.04A 2e1qC-6au1A:
undetectable		 2e1qC-6au1A:
5.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 457
VAL A 533
LEU A 470
ALA A 464
PHE A 376
 None
 1.50A 2jj8C-6au1A:
undetectable		 2jj8C-6au1A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		4 / 8 SER A 670
TYR A 645
ASP A 664
ARG A 631
 None
 1.09A 2v57A-6au1A:
undetectable		 2v57A-6au1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		4 / 8 SER A 670
TYR A 645
ASP A 664
ARG A 631
 None
 1.09A 2v57C-6au1A:
undetectable		 2v57C-6au1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 LEU A 630
ARG A 595
TRP A 593
TYR A 645
 None
SO4  A 703 (-3.9A)
None
None
 1.22A 2zlcA-6au1A:
undetectable		 2zlcA-6au1A:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LEU A 381
ASN A 378
LEU A 461
LEU A 529
LEU A 443
 None
 1.32A 3d90B-6au1A:
undetectable		 3d90B-6au1A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 GLN A 360
ALA A 361
LEU A 359
LEU A 345
ILE A 457
 None
 1.15A 3ozwB-6au1A:
undetectable		 3ozwB-6au1A:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ALA A 511
GLN A 513
ARG A 520
ILE A 519
GLU A 568
 None
 1.23A 4azwA-6au1A:
undetectable		 4azwA-6au1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 PRO A 582
ASN A 583
ILE A 625
VAL A 621
 None
 1.40A 4hytA-6au1A:
undetectable		 4hytA-6au1A:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 TYR A 404
PHE A 575
ALA A 356
SER A 355
 None
 1.23A 4lv9A-6au1A:
2.7
4lv9B-6au1A:
2.9		 4lv9A-6au1A:
9.64
4lv9B-6au1A:
9.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P7N_A_GCSA701_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 ASP A 474
MET A 581
TRP A 619
TYR A 648
 EDO  A 705 (-3.3A)
None
None
None
 0.39A 4p7nA-6au1A:
50.3		 4p7nA-6au1A:
59.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 VAL A 576
LEU A 566
SER A 565
GLU A 568
 None
 0.91A 4zphA-6au1A:
undetectable
4zphB-6au1A:
undetectable		 4zphA-6au1A:
undetectable
4zphB-6au1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 TYR A 458
LEU A 461
PHE A 467
PHE A 376
GLY A 469
 None
 1.22A 5fsaA-6au1A:
undetectable		 5fsaA-6au1A:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 VAL A 601
ALA A 550
VAL A 553
LEU A 614
ILE A 322
 None
 1.18A 5hv1A-6au1A:
undetectable		 5hv1A-6au1A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		4 / 8 HIS A 473
GLN A 324
MET A 579
TRP A 619
 EDO  A 705 ( 4.6A)
None
None
None
 1.44A 5u6nA-6au1A:
3.5		 5u6nA-6au1A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 6au1 PUTATIVE HEMIN
STORAGE PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LEU A 437
GLU A 482
ALA A 560
GLY A 563
TYR A 562
 EDO  A 705 (-4.5A)
None
None
None
None
 1.01A 5uxdB-6au1A:
undetectable		 5uxdB-6au1A:
12.37