SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6au6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT
(Homo
sapiens) 		4 / 8 SER A  51
SER A  54
GLY A 226
GLY A  47
 GDP  A 401 (-3.4A)
MG  A 402 ( 2.1A)
None
None
 0.64A 1f5lA-6au6A:
undetectable		 1f5lA-6au6A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TNL_A_TPAA900_1
(TRYPSIN)		 6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT
(Homo
sapiens) 		4 / 6 SER A  51
SER A  54
GLY A 226
GLY A  47
 GDP  A 401 (-3.4A)
MG  A 402 ( 2.1A)
None
None
 0.68A 1tnlA-6au6A:
undetectable		 1tnlA-6au6A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)		 6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT
(Homo
sapiens) 		4 / 6 SER A  51
SER A  54
GLY A 226
GLY A  47
 GDP  A 401 (-3.4A)
MG  A 402 ( 2.1A)
None
None
 0.71A 2otvA-6au6A:
undetectable		 2otvA-6au6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT
(Homo
sapiens) 		3 / 3 LYS A  91
ILE A 372
PHE A 376
 None
 0.77A 3j7zS-6au6A:
undetectable
3j7za-6au6A:
undetectable		 3j7zS-6au6A:
undetectable
3j7za-6au6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT
(Homo
sapiens) 		4 / 6 SER A 286
ILE A 382
TYR A 360
THR A 350
 None
 0.99A 3q70A-6au6A:
undetectable		 3q70A-6au6A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT
(Homo
sapiens) 		4 / 6 SER A  51
SER A  54
GLY A 226
GLY A  47
 GDP  A 401 (-3.4A)
MG  A 402 ( 2.1A)
None
None
 0.61A 3rxfA-6au6A:
undetectable		 3rxfA-6au6A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT
(Homo
sapiens) 		4 / 5 PHE A 290
TYR A 360
LEU A 297
ARG A 342
 None
 1.48A 3sudD-6au6A:
undetectable		 3sudD-6au6A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT
(Homo
sapiens) 		3 / 3 LYS A 151
ARG A 127
HIS A 149
 None
 0.85A 4zbrA-6au6A:
undetectable		 4zbrA-6au6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT
(Homo
sapiens) 		5 / 12 GLY A 353
GLY A 355
THR A 284
ASP A 354
ILE A 348
 None
 1.18A 5bw4A-6au6A:
undetectable		 5bw4A-6au6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT
(Homo
sapiens) 		4 / 4 PHE A 363
LEU A 270
LEU A 346
VAL A 248
 None
None
None
CL  A 403 ( 4.4A)
 1.17A 5xxiA-6au6A:
undetectable		 5xxiA-6au6A:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT
(Homo
sapiens) 		3 / 3 LYS A 274
ASN A 278
SER A 352
 None
 1.17A 5yw0A-6au6A:
undetectable		 5yw0A-6au6A:
undetectable