SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6au8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
(Homo
sapiens) 		5 / 11 LEU A 201
LEU A 206
LEU A 301
HIS A 165
ARG A 163
 None
None
None
None
GOL  A 401 (-3.9A)
 1.46A 1kt6A-6au8A:
undetectable		 1kt6A-6au8A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		5 / 12 GLN C1023
LEU A 266
THR A 220
ILE A 226
PHE A 232
 None
 1.35A 1p93B-6au8C:
undetectable		 1p93B-6au8C:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
(Homo
sapiens) 		3 / 3 PHE A 255
CYH A 259
PHE A 239
 None
 1.06A 3cr5X-6au8A:
undetectable		 3cr5X-6au8A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens;
Homo
sapiens) 		5 / 11 LEU A 179
SER C1038
LEU C1037
GLN A 202
ALA A 199
 None
None
None
GOL  A 401 ( 3.3A)
None
 1.40A 4hwkB-6au8A:
undetectable		 4hwkB-6au8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens;
Homo
sapiens) 		5 / 11 LEU A 179
SER C1038
LEU C1037
TYR A 182
GLN A 202
 None
None
None
None
GOL  A 401 ( 3.3A)
 1.43A 4hwkB-6au8A:
undetectable		 4hwkB-6au8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens;
Homo
sapiens) 		5 / 12 LEU A 179
SER C1038
LEU C1037
GLN A 202
ALA A 199
 None
None
None
GOL  A 401 ( 3.3A)
None
 1.38A 4hwkC-6au8A:
undetectable		 4hwkC-6au8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens;
Homo
sapiens) 		5 / 12 LEU A 179
SER C1038
LEU C1037
TYR A 182
GLN A 202
 None
None
None
None
GOL  A 401 ( 3.3A)
 1.42A 4hwkC-6au8A:
undetectable		 4hwkC-6au8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens;
Homo
sapiens) 		5 / 11 LEU A 179
SER C1038
LEU C1037
GLN A 202
ALA A 199
 None
None
None
GOL  A 401 ( 3.3A)
None
 1.39A 4hwkD-6au8A:
undetectable		 4hwkD-6au8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens;
Homo
sapiens) 		5 / 11 LEU A 179
SER C1038
LEU C1037
TYR A 182
GLN A 202
 None
None
None
None
GOL  A 401 ( 3.3A)
 1.45A 4hwkD-6au8A:
undetectable		 4hwkD-6au8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		5 / 12 SER C1038
LEU C1037
TYR A 182
GLN A 202
ASP A 193
 None
None
None
GOL  A 401 ( 3.3A)
None
 1.27A 4j7xF-6au8C:
undetectable		 4j7xF-6au8C:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		5 / 12 LEU A 179
SER C1038
LEU C1037
TYR A 182
GLN A 202
 None
None
None
None
GOL  A 401 ( 3.3A)
 1.43A 4j7xJ-6au8A:
undetectable		 4j7xJ-6au8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		5 / 12 SER C1038
LEU C1037
TYR A 182
GLN A 202
ASP A 193
 None
None
None
GOL  A 401 ( 3.3A)
None
 1.25A 4j7xJ-6au8C:
undetectable		 4j7xJ-6au8C:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		5 / 12 GLN C1023
LEU A 266
THR A 220
ILE A 226
PHE A 232
 None
 1.43A 4p6xA-6au8C:
undetectable		 4p6xA-6au8C:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		5 / 12 GLN C1023
LEU A 266
THR A 220
ILE A 226
PHE A 232
 None
 1.46A 4p6xE-6au8C:
undetectable		 4p6xE-6au8C:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		5 / 12 GLN C1023
LEU A 266
THR A 220
ILE A 226
PHE A 232
 None
 1.47A 4p6xG-6au8C:
undetectable		 4p6xG-6au8C:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		5 / 12 GLN C1023
LEU A 266
THR A 220
ILE A 226
PHE A 232
 None
 1.46A 4p6xI-6au8C:
undetectable		 4p6xI-6au8C:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		5 / 12 LEU A 236
GLN C1023
THR A 220
ILE A 226
PHE A 232
 None
 1.46A 4udcA-6au8A:
undetectable		 4udcA-6au8A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
(Homo
sapiens) 		4 / 7 TYR A 275
GLY A 299
SER A 304
LEU A 301
 None
 1.21A 5bphB-6au8A:
undetectable		 5bphB-6au8A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
(Homo
sapiens) 		4 / 6 TYR A 275
GLY A 299
SER A 304
LEU A 301
 None
 1.19A 5bphD-6au8A:
undetectable		 5bphD-6au8A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
(Homo
sapiens) 		4 / 8 GLY A 229
TRP A 241
PHE A 216
TYR A 219
 None
 1.05A 6eqpA-6au8A:
undetectable		 6eqpA-6au8A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
(Homo
sapiens) 		4 / 7 GLY A  77
PHE A  74
HIS A  76
SER A  81
 None
 0.99A 6hu9S-6au8A:
undetectable
6hu9q-6au8A:
undetectable		 6hu9S-6au8A:
13.43
6hu9q-6au8A:
19.37