SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6aun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 7 THR A 531
THR A 466
GLY A 431
ASP A 430
None
1.01A 1bu5A-6aunA:
undetectable
1bu5A-6aunA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 10 PHE A 190
ASN A 198
ALA A 193
LEU A 168
VAL A 169
None
1.31A 1claA-6aunA:
undetectable
1claA-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 4 THR A 345
PRO A 353
THR A 352
PRO A 346
None
1.32A 1dsdC-6aunA:
undetectable
1dsdC-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 4 THR A 345
PRO A 353
THR A 352
PRO A 346
None
1.32A 1dsdC-6aunA:
undetectable
1dsdC-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 7 SER A 696
ARG A 693
VAL A 636
ALA A 688
None
1.04A 1fo4B-6aunA:
undetectable
1fo4B-6aunA:
5.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 8 THR A 345
PRO A 346
GLY A 347
THR A 313
None
0.76A 1h4oB-6aunA:
undetectable
1h4oB-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 8 THR A 345
PRO A 346
GLY A 347
THR A 313
None
0.74A 1oc3A-6aunA:
undetectable
1oc3A-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 7 ALA A 586
TYR A 589
TYR A 487
PHE A 495
None
1.16A 2ajvH-6aunA:
undetectable
2ajvL-6aunA:
undetectable
2ajvH-6aunA:
15.53
2ajvL-6aunA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 12 GLY A 266
VAL A 236
ALA A 259
ALA A 268
ARG A 306
None
1.42A 2avdB-6aunA:
undetectable
2avdB-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 11 LEU A 506
VAL A 576
ALA A 579
LEU A 575
LEU A 510
None
1.29A 2c12F-6aunA:
undetectable
2c12F-6aunA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 9 PHE A 372
GLY A 373
GLU A 375
ILE A 444
ALA A 481
None
1.30A 2drdA-6aunA:
undetectable
2drdA-6aunA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 6 ARG A 555
GLU A 616
PRO A 551
ALA A 550
None
1.38A 2ejfB-6aunA:
undetectable
2ejfB-6aunA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 12 ALA A 471
GLY A 468
GLY A 463
ALA A 610
GLY A 532
None
0.90A 2pkmA-6aunA:
undetectable
2pkmA-6aunA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
3 / 3 PRO A 587
ASN A 593
ARG A 581
None
0.95A 2qeuB-6aunA:
2.3
2qeuB-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 11 LEU A 457
LEU A 639
VAL A 637
LEU A 750
ILE A 735
None
1.06A 2uxoB-6aunA:
undetectable
2uxoB-6aunA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 7 PRO A 708
LEU A 442
ALA A 445
PHE A 742
None
0.81A 2vcvG-6aunA:
undetectable
2vcvG-6aunA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 7 THR A 345
PRO A 346
GLY A 347
THR A 313
None
0.72A 2vl2B-6aunA:
undetectable
2vl2B-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
3 / 3 CYH A 681
PRO A 684
ASP A 598
None
0.86A 3hlwB-6aunA:
undetectable
3hlwB-6aunA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
3 / 3 SER A 394
ASP A 361
ASP A 399
None
0.76A 3iv6C-6aunA:
undetectable
3iv6C-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 11 ALA A 580
VAL A 576
ILE A 469
GLY A 468
LEU A 510
None
1.18A 3kw2B-6aunA:
undetectable
3kw2B-6aunA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_C_NCAC302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 10 TYR A 703
LEU A 608
ASP A 609
ALA A 610
ALA A 603
None
1.48A 3rodC-6aunA:
undetectable
3rodC-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 12 PHE A 458
ILE A 614
ALA A 610
THR A 607
LEU A 706
None
1.16A 3s79A-6aunA:
undetectable
3s79A-6aunA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 12 GLY A 463
LEU A 597
GLY A 532
SER A 583
ALA A 586
None
1.03A 3sufA-6aunA:
undetectable
3sufA-6aunA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_C_ACTC207_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 4 LYS A 566
PRO A 567
LEU A 565
ASN A 560
None
1.47A 3tpxC-6aunA:
undetectable
3tpxC-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 12 GLY A 468
ASP A 598
ASN A 593
SER A 503
LEU A 510
None
1.45A 4a83A-6aunA:
undetectable
4a83A-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 10 LEU A 437
GLY A 433
ASP A 430
GLY A 468
ILE A 469
None
1.00A 4njtB-6aunA:
undetectable
4njtB-6aunA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 6 ALA A 688
ASP A 685
LEU A 608
SER A 696
None
1.06A 4ot2A-6aunA:
2.5
4ot2A-6aunA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 6 ARG A 705
ALA A 688
ASP A 685
LEU A 608
None
1.14A 4ot2A-6aunA:
2.5
4ot2A-6aunA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
3 / 3 CYH A 681
PRO A 684
ASP A 598
None
0.95A 4pm5A-6aunA:
undetectable
4pm5A-6aunA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
3 / 3 SER A 638
TYR A 703
ASP A 685
None
0.87A 4rp8C-6aunA:
undetectable
4rp8C-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 4 GLY A 532
LEU A 510
PHE A 509
ILE A 469
None
0.96A 4xv2A-6aunA:
undetectable
4xv2A-6aunA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 6 ASP A 430
ALA A 462
THR A 464
THR A 531
None
1.48A 4z4fA-6aunA:
4.7
4z4fA-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 5 ASP A 430
ALA A 462
THR A 464
THR A 531
None
1.48A 4z4gA-6aunA:
4.5
4z4gA-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 6 ASP A 430
ALA A 462
THR A 464
THR A 531
None
1.42A 4z4iA-6aunA:
4.7
4z4iA-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 12 GLY A 463
LEU A 470
THR A 464
GLY A 599
GLY A 436
None
1.14A 5d4uA-6aunA:
undetectable
5d4uA-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 9 PHE A 372
GLY A 373
GLU A 375
ILE A 444
ALA A 481
None
1.42A 5entC-6aunA:
undetectable
5entC-6aunA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 12 LEU A 470
LEU A 457
LEU A 429
ILE A 635
LEU A 745
None
1.19A 5ienB-6aunA:
undetectable
5ienB-6aunA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 12 PHE A 458
ILE A 614
ALA A 610
THR A 607
LEU A 706
None
1.16A 5jkvA-6aunA:
undetectable
5jkvA-6aunA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 6 VAL A 461
LEU A 442
ILE A 735
PHE A 742
None
0.97A 5jw1A-6aunA:
undetectable
5jw1A-6aunA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 11 LEU A 530
GLY A 599
LEU A 472
ARG A 581
ALA A 579
None
1.05A 5o96A-6aunA:
undetectable
5o96B-6aunA:
undetectable
5o96A-6aunA:
undetectable
5o96B-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 12 VAL A 486
LEU A 437
LEU A 470
ILE A 474
ALA A 473
None
1.40A 5xprA-6aunA:
2.5
5xprA-6aunA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 12 GLY A 431
GLY A 467
ASN A 604
SER A 583
TYR A 487
None
1.38A 5yf0A-6aunA:
undetectable
5yf0A-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
4 / 6 SER A 503
ARG A 595
ARG A 578
ASP A 536
None
1.06A 5zw4A-6aunA:
undetectable
5zw4A-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
6 / 12 GLY A 485
VAL A 486
PHE A 509
THR A 466
GLY A 467
GLY A 468
None
1.41A 6brdB-6aunA:
undetectable
6brdB-6aunA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 12 GLY A 468
LEU A 597
GLY A 532
SER A 583
ALA A 586
None
1.05A 6c2mA-6aunA:
undetectable
6c2mA-6aunA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)
6aun PLA2G6, IPLA2BETA
(Cricetulus
griseus)
5 / 11 PHE A 704
LEU A 706
ILE A 635
PHE A 742
ILE A 446
None
0.94A 6ebzC-6aunA:
undetectable
6ebzC-6aunA:
23.33