SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6avf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA181_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 4 THR H 190
ARG H 202
HIS H 192
HIS H 191
 None
 1.21A 1gtnA-6avfH:
0.6		 1gtnA-6avfH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 8 LEU H 172
VAL H 103
GLY H 104
GLU H 180
 None
 0.94A 1jlfA-6avfH:
undetectable
1jlfB-6avfH:
undetectable		 1jlfA-6avfH:
10.08
1jlfB-6avfH:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 6 ASN H  63
TYR H   7
TYR H 171
TYR H  59
 None
 1.40A 1kiaA-6avfH:
undetectable		 1kiaA-6avfH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 6 ASN H  63
TYR H   7
TYR H 171
TYR H  59
 None
 1.40A 1kiaB-6avfH:
undetectable		 1kiaB-6avfH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  63
TYR H   7
TYR H 171
TYR H  59
 None
 1.39A 1kiaC-6avfH:
0.4		 1kiaC-6avfH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  63
TYR H   7
TYR H 171
TYR H  59
 None
 1.40A 1kiaD-6avfH:
undetectable		 1kiaD-6avfH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 6 ASN H  63
TYR H   7
TYR H 171
TYR H  59
 None
 1.42A 1nbhA-6avfH:
0.5		 1nbhA-6avfH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  63
TYR H   7
TYR H 171
TYR H  59
 None
 1.41A 1nbhB-6avfH:
undetectable		 1nbhB-6avfH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 6 ASN H  63
TYR H   7
TYR H 171
TYR H  59
 None
 1.42A 1nbhC-6avfH:
undetectable		 1nbhC-6avfH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  63
TYR H   7
TYR H 171
TYR H  59
 None
 1.42A 1nbhD-6avfH:
undetectable		 1nbhD-6avfH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		5 / 10 ALA H  49
THR H  31
LEU H 179
MET H   5
VAL H  28
 None
 1.36A 2wuzA-6avfH:
undetectable		 2wuzA-6avfH:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		5 / 10 ALA H  49
THR H  31
LEU H 179
MET H   5
VAL H  28
 None
 1.33A 2wuzB-6avfH:
undetectable		 2wuzB-6avfH:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 8 TYR H 123
TYR H  84
TYR H 118
HIS H  93
 None
 0.94A 2zm8A-6avfH:
undetectable		 2zm8A-6avfH:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 8 TYR H 123
TYR H  84
TYR H 118
HIS H  93
 None
 1.01A 2zmaA-6avfH:
undetectable		 2zmaA-6avfH:
12.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		6 / 10 TYR H   9
TYR H  99
ASP H 114
TYR H 123
ILE H 124
TRP H 147
 None
 0.43A 3uprA-6avfH:
33.6		 3uprA-6avfH:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		6 / 10 TYR H   9
TYR H  99
ASP H 114
TYR H 123
ILE H 124
TRP H 147
 None
 0.46A 3uprC-6avfH:
33.9		 3uprC-6avfH:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VRI_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		6 / 10 TYR H   9
TYR H  99
ASP H 114
TYR H 123
ILE H 124
TRP H 147
 None
 0.56A 3vriA-6avfH:
33.3
3vriC-6avfH:
undetectable		 3vriA-6avfH:
91.07
3vriC-6avfH:
14.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		6 / 12 TYR H   9
TYR H  99
ASP H 114
TYR H 123
ILE H 124
TRP H 147
 None
 0.51A 3vrjA-6avfH:
33.3
3vrjC-6avfH:
undetectable		 3vrjA-6avfH:
91.07
3vrjC-6avfH:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 7 THR H 214
LEU H 215
LEU H 272
THR H 216
 None
 0.85A 4z91F-6avfH:
undetectable
4z91G-6avfH:
undetectable
4z91H-6avfH:
undetectable
4z91I-6avfH:
undetectable
4z91J-6avfH:
undetectable		 4z91F-6avfH:
13.03
4z91G-6avfH:
13.03
4z91H-6avfH:
13.03
4z91I-6avfH:
13.03
4z91J-6avfH:
13.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		6 / 10 TYR H   9
TYR H  99
ASP H 114
TYR H 123
ILE H 124
TRP H 147
 None
 0.43A 5u98A-6avfH:
33.9		 5u98A-6avfH:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		6 / 10 TYR H   9
TYR H  99
ASP H 114
TYR H 123
ILE H 124
TRP H 147
 None
 0.42A 5u98D-6avfH:
33.7		 5u98D-6avfH:
65.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_2
(ADENOSYLHOMOCYSTEINA
SE)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 4 GLU H 232
THR H 233
GLU H 212
HIS H   3
 None
 1.43A 5utuF-6avfH:
undetectable		 5utuF-6avfH:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN
(Homo
sapiens) 		4 / 5 ALA H 135
TYR H 123
GLN H 141
ILE H 142
 None
 1.30A 6f6sA-6avfH:
undetectable
6f6sB-6avfH:
0.0		 6f6sA-6avfH:
20.00
6f6sB-6avfH:
15.85