SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6avw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 6avw CARBOXYLESTERASE
SOBER1
(Arabidopsis
thaliana) 		3 / 3 ALA A  63
VAL A 163
TRP A 132
 None
 0.94A 1magA-6avwA:
undetectable		 1magA-6avwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 6avw CARBOXYLESTERASE
SOBER1
(Arabidopsis
thaliana) 		3 / 3 ALA A  63
VAL A 163
TRP A 132
 None
 0.94A 1magB-6avwA:
undetectable		 1magB-6avwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6avw CARBOXYLESTERASE
SOBER1
(Arabidopsis
thaliana) 		5 / 11 ILE A 206
PHE A  26
SER A 195
ILE A 194
ILE A 202
 None
 1.14A 2blaA-6avwA:
undetectable		 2blaA-6avwA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6avw CARBOXYLESTERASE
SOBER1
(Arabidopsis
thaliana) 		5 / 10 ILE A 206
PHE A  26
SER A 195
ILE A 194
ILE A 202
 None
 1.18A 3um5A-6avwA:
undetectable		 3um5A-6avwA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6avw CARBOXYLESTERASE
SOBER1
(Arabidopsis
thaliana) 		5 / 10 ILE A 206
PHE A  26
SER A 195
ILE A 194
ILE A 202
 None
 1.21A 3um5B-6avwA:
undetectable		 3um5B-6avwA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 6avw CARBOXYLESTERASE
SOBER1
(Arabidopsis
thaliana) 		5 / 11 ILE A 206
PHE A  26
SER A 195
ILE A 194
ILE A 202
 None
 1.25A 4p68A-6avwA:
undetectable		 4p68A-6avwA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 6avw CARBOXYLESTERASE
SOBER1
(Arabidopsis
thaliana) 		3 / 3 ASP A 160
GLU A 198
SER A  69
 None
 0.64A 5bw4B-6avwA:
2.7		 5bw4B-6avwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 6avw CARBOXYLESTERASE
SOBER1
(Arabidopsis
thaliana) 		5 / 12 GLY A 109
GLY A 108
LEU A 111
GLY A 124
PRO A  39
 None
 0.94A 6gngB-6avwA:
5.6		 6gngB-6avwA:
7.67