SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ayh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BNN_B_FCNB1199_1 (EPOXIDASE)	6ayh	TETR FAMILY TRANSCRIPTIONAL REGULATOR (Salmonella enterica)	4 / 8	TYR A 166 LEU A 169 GLU A 99 HIS A 75	C3G A 302 (-4.5A) None C3G A 302 (-2.7A) C3G A 302 (-4.0A)	0.95A	2bnnA-6ayhA: undetectable 2bnnB-6ayhA: undetectable	2bnnA-6ayhA: 17.10 2bnnB-6ayhA: 17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3001_1 (TRANSCRIPTIONAL REGULATOR TCAR)	6ayh	TETR FAMILY TRANSCRIPTIONAL REGULATOR (Salmonella enterica)	4 / 8	GLU A 122 HIS A 129 ASN A 126 ILE A 65	None	1.30A	3kp6A-6ayhA: undetectable 3kp6B-6ayhA: undetectable	3kp6A-6ayhA: 19.73 3kp6B-6ayhA: 19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PAE_A_NIZA804_1 (CATALASE-PEROXIDASE)	6ayh	TETR FAMILY TRANSCRIPTIONAL REGULATOR (Salmonella enterica)	4 / 6	PHE A 76 TYR A 88 LEU A 89 THR A 165	C3G A 302 (-4.7A) None C3G A 302 ( 4.9A) C3G A 302 (-3.3A)	1.30A	4paeA-6ayhA: undetectable	4paeA-6ayhA: 6.87

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BNN_B_FCNB1199_1","EPOXIDASE;EPOXIDASE","6ayh","TETR FAMILY TRANSCRIPTIONAL REGULATOR","Salmonella enterica",4,"TYR A 166;LEU A 169;GLU A  99;HIS A  75","C3G A 302 (-4.5A);None;C3G A 302 (-2.7A);C3G A 302 (-4.0A)","0.95A","2bnnA-6ayhA:undetectable;2bnnB-6ayhA:undetectable","2bnnA-6ayhA:17.10;2bnnB-6ayhA:17.10"],["3KP6_B_SALB3001_1","TRANSCRIPTIONAL REGULATOR TCAR;TRANSCRIPTIONAL REGULATOR TCAR","6ayh","TETR FAMILY TRANSCRIPTIONAL REGULATOR","Salmonella enterica",4,"GLU A 122;HIS A 129;ASN A 126;ILE A  65","None","1.30A","3kp6A-6ayhA:undetectable;3kp6B-6ayhA:undetectable","3kp6A-6ayhA:19.73;3kp6B-6ayhA:19.73"],["4PAE_A_NIZA804_1","CATALASE-PEROXIDASE","6ayh","TETR FAMILY TRANSCRIPTIONAL REGULATOR","Salmonella enterica",4,"PHE A  76;TYR A  88;LEU A  89;THR A 165","C3G A 302 (-4.7A);None;C3G A 302 ( 4.9A);C3G A 302 (-3.3A)","1.30A","4paeA-6ayhA:undetectable","4paeA-6ayhA:6.87"]]