SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6az5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 6az5 ALPHA-AMYLASE
([Eubacterium]
rectale) 		5 / 12 LEU A 404
GLY A 472
GLY A 471
ALA A 461
TRP A 416
 None
 1.11A 3i5uA-6az5A:
undetectable		 3i5uA-6az5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 6az5 ALPHA-AMYLASE
([Eubacterium]
rectale) 		5 / 12 LEU A 404
GLY A 472
GLY A 471
ALA A 461
TRP A 416
 None
 1.08A 3i5uB-6az5A:
undetectable		 3i5uB-6az5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 6az5 ALPHA-AMYLASE
([Eubacterium]
rectale) 		4 / 7 ASN A 437
TYR A 492
LEU A 490
PHE A 395
 None
 0.91A 4yv5A-6az5A:
undetectable		 4yv5A-6az5A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 6az5 ALPHA-AMYLASE
([Eubacterium]
rectale) 		4 / 7 ASN A 437
TYR A 492
LEU A 490
PHE A 395
 None
 1.07A 4yv5B-6az5A:
undetectable		 4yv5B-6az5A:
18.40