SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6azh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 6azh TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Clostridium
perfringens) 		4 / 5 TYR A  92
ILE A  69
LEU A  66
LYS A  65
 None
 1.01A 3sueC-6azhA:
undetectable		 3sueC-6azhA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 6azh TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Clostridium
perfringens) 		4 / 6 GLU A  10
ILE A  13
ASN A  14
GLU A 162
 None
 0.64A 4ejwB-6azhA:
undetectable		 4ejwB-6azhA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6azh TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Clostridium
perfringens) 		4 / 7 PHE A   9
ILE A  13
GLY A  58
LEU A  90
 None
 0.84A 4ze3A-6azhA:
2.7		 4ze3A-6azhA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 6azh TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Clostridium
perfringens) 		4 / 5 GLN A  87
ILE A 126
ILE A 129
TYR A 122
 None
 1.20A 5dnuA-6azhA:
undetectable		 5dnuA-6azhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 6azh TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Clostridium
perfringens) 		4 / 5 GLN A  87
ILE A 126
ILE A 129
TYR A 122
 None
 1.13A 5dnvA-6azhA:
undetectable		 5dnvA-6azhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6azh TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Clostridium
perfringens) 		4 / 7 PHE A   9
ILE A  13
GLY A  58
LEU A  90
 None
 0.95A 5esmA-6azhA:
undetectable		 5esmA-6azhA:
10.19