SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6azp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 6 GLY A 542
ASP A 371
GLY A 708
SER A 414
 None
 0.95A 1eswA-6azpA:
undetectable		 1eswA-6azpA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 6azp STAPHYLOCOCCAL
PEROXIDASE INHIBITOR
(Staphylococcus
aureus) 		4 / 4 HIS B  82
ALA B  77
PHE B  76
GLY B  80
 None
 0.98A 1mj2B-6azpB:
undetectable		 1mj2B-6azpB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 6azp STAPHYLOCOCCAL
PEROXIDASE INHIBITOR
(Staphylococcus
aureus) 		4 / 4 HIS B  82
ALA B  77
PHE B  76
GLY B  80
 None
 1.04A 1mj2D-6azpB:
undetectable		 1mj2D-6azpB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 6azp STAPHYLOCOCCAL
PEROXIDASE INHIBITOR
(Staphylococcus
aureus) 		4 / 4 HIS B  82
ALA B  77
PHE B  76
GLY B  80
 None
 0.99A 1mjoB-6azpB:
undetectable		 1mjoB-6azpB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 6azp STAPHYLOCOCCAL
PEROXIDASE INHIBITOR
(Staphylococcus
aureus) 		4 / 4 HIS B  82
ALA B  77
PHE B  76
GLY B  80
 None
 1.01A 1mjoA-6azpB:
undetectable		 1mjoA-6azpB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 6azp STAPHYLOCOCCAL
PEROXIDASE INHIBITOR
(Staphylococcus
aureus) 		4 / 4 HIS B  82
ALA B  77
PHE B  76
GLY B  80
 None
 0.99A 1mjoD-6azpB:
undetectable		 1mjoD-6azpB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		6 / 11 LEU A 630
GLY A 645
GLY A 646
VAL A 657
LEU A 661
LEU A 626
 None
 1.44A 1mx1A-6azpA:
undetectable		 1mx1A-6azpA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 6azp MYELOPEROXIDASE
STAPHYLOCOCCAL
PEROXIDASE INHIBITOR
(Homo
sapiens;
Staphylococcus
aureus) 		5 / 12 GLY A 439
ASN A 358
ASN A 355
LEU B  49
LEU B  72
 None
NAG  A 802 (-3.6A)
NAG  A 802 (-1.6A)
None
None
 1.10A 1r30A-6azpA:
undetectable		 1r30A-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 6azp MYELOPEROXIDASE
STAPHYLOCOCCAL
PEROXIDASE INHIBITOR
(Homo
sapiens;
Staphylococcus
aureus) 		5 / 12 GLY A 439
ASN A 358
ASN A 355
LEU B  49
LEU B  72
 None
NAG  A 802 (-3.6A)
NAG  A 802 (-1.6A)
None
None
 1.10A 1r30B-6azpA:
undetectable		 1r30B-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 7 ARG A 653
ALA A 471
PRO A 659
ALA A 662
 None
 1.02A 2ejfA-6azpA:
2.0		 2ejfA-6azpA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 6 LEU A 377
VAL A 525
MET A 509
ILE A 546
 None
 1.13A 2hyyC-6azpA:
undetectable		 2hyyC-6azpA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 12 ARG A 405
ILE A 568
HIS A 502
GLY A 256
LEU A 661
 None
 1.27A 2nyrB-6azpA:
undetectable		 2nyrB-6azpA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 7 LEU A 738
GLU A 429
ILE A 449
ILE A 176
 None
 0.78A 2xkwA-6azpA:
undetectable		 2xkwA-6azpA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 7 LEU A 738
ILE A 449
ALA A 350
ILE A 176
 None
 0.71A 2xkwA-6azpA:
undetectable		 2xkwA-6azpA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 7 TRP A 679
VAL A 337
THR A 458
LEU A 463
 None
 1.18A 3arrA-6azpA:
undetectable		 3arrA-6azpA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6azp MYELOPEROXIDASE
STAPHYLOCOCCAL
PEROXIDASE INHIBITOR
(Homo
sapiens;
Staphylococcus
aureus) 		4 / 7 LEU B  49
ARG A 351
SER A 406
GLY A 344
 None
 1.04A 3hcrB-6azpB:
undetectable		 3hcrB-6azpB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGW_A_IMNA597_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 9 GLN A 257
HIS A 261
PHE A 265
ARG A 405
PHE A 532
 None
 0.54A 3ogwA-6azpA:
60.5		 3ogwA-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGW_A_IMNA597_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 9 GLN A 257
HIS A 261
PHE A 265
ARG A 405
PHE A 573
 None
 1.05A 3ogwA-6azpA:
60.5		 3ogwA-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGW_A_IMNA597_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 9 GLN A 257
HIS A 261
PHE A 265
GLU A 268
PHE A 532
 None
 0.79A 3ogwA-6azpA:
60.5		 3ogwA-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGW_A_IMNA597_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 9 GLN A 257
HIS A 261
PHE A 265
GLU A 268
PHE A 573
 None
 1.34A 3ogwA-6azpA:
60.5		 3ogwA-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PY4_A_TYLA598_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
ARG A 405
PHE A 532
 None
 0.47A 3py4A-6azpA:
61.3		 3py4A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PY4_A_TYLA598_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
ARG A 405
PHE A 573
 None
 0.95A 3py4A-6azpA:
61.3		 3py4A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PY4_A_TYLA598_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
GLU A 408
PHE A 532
 None
 1.20A 3py4A-6azpA:
61.3		 3py4A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 7 GLN A 257
HIS A 261
ARG A 405
PHE A 532
PRO A 386
 None
 1.39A 3ql6A-6azpA:
55.0		 3ql6A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 7 GLN A 257
HIS A 261
GLU A 268
ARG A 405
PHE A 532
 None
 0.86A 3ql6A-6azpA:
55.0		 3ql6A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 7 GLN A 257
HIS A 261
GLU A 268
ARG A 405
PHE A 573
 None
 1.19A 3ql6A-6azpA:
55.0		 3ql6A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
ASP A 260
HIS A 261
ARG A 405
 None
 0.48A 3r4xA-6azpA:
54.8		 3r4xA-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
ASP A 260
HIS A 261
GLU A 408
 None
 0.94A 3r4xA-6azpA:
54.8		 3r4xA-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
ASP A 260
HIS A 261
ARG A 405
 None
 0.48A 3r55A-6azpA:
55.0		 3r55A-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
ASP A 260
HIS A 261
GLU A 408
 None
 1.04A 3r55A-6azpA:
55.0		 3r55A-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 8 GLY A 666
TYR A 459
PRO A 464
ARG A 673
 None
 0.91A 3s3nA-6azpA:
undetectable		 3s3nA-6azpA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S68_A_SAMA228_0
(CATECHOL
O-METHYLTRANSFERASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 10 GLY A 598
TYR A 211
SER A 591
GLU A 202
ASP A 641
 None
 1.45A 3s68A-6azpA:
undetectable		 3s68A-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 LEU A 476
ARG A 673
ILE A 456
ARG A 460
 None
 1.00A 3ticA-6azpA:
undetectable		 3ticA-6azpA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		3 / 3 TYR A 173
MET A 453
LEU A 426
 None
 0.96A 3vw1D-6azpA:
undetectable		 3vw1D-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 7 PHE A 669
VAL A 466
GLY A 256
PHE A 494
 None
 0.78A 4ejjB-6azpA:
undetectable		 4ejjB-6azpA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		3 / 3 ARG A 569
TYR A 500
ASN A 496
 None
 0.84A 4ffwB-6azpA:
undetectable		 4ffwB-6azpA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 12 LEU A 360
LEU A 362
ASN A 355
LEU A 363
ALA A 364
 None
None
NAG  A 802 (-1.6A)
None
NAG  A 802 (-3.7A)
 1.22A 4fn9B-6azpA:
undetectable		 4fn9B-6azpA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
ARG A 405
LEU A 412
 None
 0.45A 4ig5A-6azpA:
54.7		 4ig5A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
GLU A 408
LEU A 412
 None
 0.95A 4ig5A-6azpA:
54.7		 4ig5A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
ARG A 405
LEU A 412
 None
 0.40A 4ig5B-6azpA:
54.9		 4ig5B-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
GLU A 408
LEU A 412
 None
 0.99A 4ig5B-6azpA:
54.9		 4ig5B-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		3 / 3 ARG A 628
LYS A 629
LYS A 625
 None
 1.34A 4k50A-6azpA:
undetectable		 4k50A-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		3 / 3 ARG A 628
LYS A 629
LYS A 625
 None
 1.36A 4k50E-6azpA:
undetectable		 4k50E-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		3 / 3 ARG A 628
LYS A 629
LYS A 625
 None
 1.37A 4k50I-6azpA:
undetectable		 4k50I-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 9 TYR A 634
VAL A 235
ILE A 563
LEU A 617
LEU A 621
 None
 1.36A 4l1xB-6azpA:
undetectable		 4l1xB-6azpA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		3 / 3 HIS A 594
TRP A 602
SER A 315
 None
None
CSO  A 316 ( 4.4A)
 1.06A 4lrhD-6azpA:
undetectable		 4lrhD-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_1
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 SER A 591
GLU A 202
ASP A 641
ASN A 638
 None
 1.33A 4pclA-6azpA:
0.3		 4pclA-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		3 / 3 GLN A 257
HIS A 261
ARG A 405
 None
 0.50A 4qyqA-6azpA:
54.0		 4qyqA-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		3 / 3 GLN A 257
HIS A 261
ARG A 405
 None
 0.43A 4qyqB-6azpA:
53.9		 4qyqB-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 6 GLN A 257
ASP A 260
HIS A 261
ARG A 405
ARG A 499
 None
 0.58A 4qyqC-6azpA:
16.8		 4qyqC-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 6 GLN A 257
ASP A 260
HIS A 261
GLU A 408
ARG A 499
 None
 1.09A 4qyqC-6azpA:
16.8		 4qyqC-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 12 GLN A 506
LEU A 557
LEU A 527
GLU A 567
PHE A 237
 None
 1.18A 4retA-6azpA:
undetectable		 4retA-6azpA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 12 GLN A 506
LEU A 557
LEU A 527
GLU A 567
PHE A 237
 None
 1.18A 4retC-6azpA:
undetectable		 4retC-6azpA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		3 / 3 GLU A 347
TYR A 443
GLU A 440
 None
 0.82A 4ryaA-6azpA:
undetectable		 4ryaA-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLY A 598
SER A 591
GLU A 202
ASP A 641
 None
 1.19A 4xueA-6azpA:
undetectable		 4xueA-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 12 TYR A 634
VAL A 235
ILE A 563
LEU A 617
LEU A 621
 None
 1.22A 4yvpB-6azpA:
undetectable		 4yvpB-6azpA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 11 MET A 644
GLY A 646
THR A 495
ARG A 592
GLY A 598
 None
 1.48A 5b1aA-6azpA:
undetectable
5b1aB-6azpA:
undetectable
5b1aT-6azpA:
undetectable		 5b1aA-6azpA:
undetectable
5b1aB-6azpA:
undetectable
5b1aT-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 11 MET A 644
GLY A 646
THR A 495
ARG A 592
GLY A 598
 None
 1.50A 5b3sA-6azpA:
undetectable
5b3sB-6azpA:
undetectable
5b3sT-6azpA:
undetectable		 5b3sA-6azpA:
undetectable
5b3sB-6azpA:
undetectable
5b3sT-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 6azp STAPHYLOCOCCAL
PEROXIDASE INHIBITOR
(Staphylococcus
aureus) 		4 / 8 ILE B  88
LYS B  90
VAL B  98
GLN B  93
 None
 0.89A 5dqyA-6azpB:
undetectable		 5dqyA-6azpB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
ARG A 405
LEU A 412
 None
 0.37A 5ff1A-6azpA:
54.8		 5ff1A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
GLU A 408
LEU A 412
 None
 0.98A 5ff1A-6azpA:
54.8		 5ff1A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
ARG A 405
LEU A 412
 None
 0.37A 5ff1A-6azpA:
54.8		 5ff1A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
GLU A 408
LEU A 412
 None
 0.98A 5ff1A-6azpA:
54.8		 5ff1A-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
ARG A 405
LEU A 412
 None
 0.37A 5ff1B-6azpA:
61.3		 5ff1B-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
GLU A 408
LEU A 412
 None
 0.97A 5ff1B-6azpA:
61.3		 5ff1B-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
ARG A 405
LEU A 412
 None
 0.37A 5ff1B-6azpA:
61.3		 5ff1B-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
GLU A 408
LEU A 412
 None
 0.97A 5ff1B-6azpA:
61.3		 5ff1B-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHQ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 9 GLY A 598
TYR A 211
SER A 591
GLU A 202
ASP A 641
 None
 1.46A 5fhqA-6azpA:
0.0		 5fhqA-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 6 LEU A 258
LEU A 547
LEU A 550
LEU A 699
 None
 1.01A 5gs4A-6azpA:
undetectable		 5gs4A-6azpA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLY A 615
PRO A 609
THR A 619
THR A 613
 None
 1.27A 5h5fA-6azpA:
undetectable		 5h5fA-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_A_3CJA609_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 5 GLN A 257
HIS A 261
ARG A 405
ARG A 499
 None
 0.54A 5hpwA-6azpA:
54.0		 5hpwA-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_B_3CJB609_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 4 GLN A 257
HIS A 261
ARG A 405
ARG A 499
 None
 0.51A 5hpwB-6azpA:
53.9		 5hpwB-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 6 GLN A 257
ASP A 260
HIS A 261
ARG A 405
ARG A 499
 None
 0.58A 5hpwC-6azpA:
16.8		 5hpwC-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 6 GLN A 257
ASP A 260
HIS A 261
GLU A 408
ARG A 499
 None
 1.09A 5hpwC-6azpA:
16.8		 5hpwC-6azpA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 12 PHE A 686
LEU A 426
ILE A 702
ALA A 339
LEU A 419
 None
 1.32A 5ienA-6azpA:
undetectable		 5ienA-6azpA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 12 THR A 334
THR A 177
ARG A 447
SER A 340
GLY A 344
 CA  A 806 (-3.6A)
None
None
CA  A 806 (-1.9A)
None
 1.32A 5l5zV-6azpA:
undetectable
5l5zb-6azpA:
undetectable		 5l5zV-6azpA:
16.07
5l5zb-6azpA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 12 THR A 334
THR A 177
ARG A 447
SER A 340
GLY A 344
 CA  A 806 (-3.6A)
None
None
CA  A 806 (-1.9A)
None
 1.32A 5l5zH-6azpA:
undetectable
5l5zN-6azpA:
undetectable		 5l5zH-6azpA:
16.07
5l5zN-6azpA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 12 THR A 334
THR A 177
ARG A 447
SER A 340
GLY A 344
 CA  A 806 (-3.6A)
None
None
CA  A 806 (-1.9A)
None
 1.31A 5lf3b-6azpA:
undetectable		 5lf3b-6azpA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 12 THR A 334
THR A 177
ARG A 447
SER A 340
GLY A 344
 CA  A 806 (-3.6A)
None
None
CA  A 806 (-1.9A)
None
 1.31A 5lf3N-6azpA:
undetectable		 5lf3N-6azpA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 9 TYR A 462
ILE A 457
ILE A 697
LEU A 694
 None
 0.78A 5vkqB-6azpA:
undetectable
5vkqC-6azpA:
undetectable		 5vkqB-6azpA:
undetectable
5vkqC-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		5 / 10 MET A 644
GLY A 646
THR A 495
ARG A 592
GLY A 598
 None
 1.48A 5wauA-6azpA:
0.5
5wauB-6azpA:
undetectable
5waug-6azpA:
undetectable		 5wauA-6azpA:
undetectable
5wauB-6azpA:
undetectable
5waug-6azpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 6azp MYELOPEROXIDASE
(Homo
sapiens) 		4 / 6 GLY A 598
TYR A 599
LEU A 199
VAL A 493
 None
 0.98A 5x80A-6azpA:
undetectable
5x80B-6azpA:
undetectable		 5x80A-6azpA:
18.75
5x80B-6azpA:
18.75