SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b0e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G4L_D_ROFD904_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	6b0e	1260 ANTIBODY, HEAVY CHAIN (Homo sapiens)	3 / 3	ASN B 76 MET B 69 PHE B 34	None	1.04A	3g4lD-6b0eB: undetectable	3g4lD-6b0eB: 16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_D_SAMD401_1 (METHYLTRANSFERASE NSUN4)	6b0e	1260 ANTIBODY, HEAVY CHAIN (Homo sapiens)	3 / 3	ASP B 95 ARG B 96 ASP B 58	None	0.76A	4fp9D-6b0eB: undetectable	4fp9D-6b0eB: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FZV_A_SAMA401_1 (PUTATIVE METHYLTRANSFERASE NSUN4)	6b0e	1260 ANTIBODY, HEAVY CHAIN (Homo sapiens)	3 / 3	ASP B 95 ARG B 96 ASP B 58	None	0.73A	4fzvA-6b0eB: undetectable	4fzvA-6b0eB: 21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FXF_B_BEZB601_0 (EUGENOL OXIDASE)	6b0e	1260 ANTIBODY, HEAVY CHAIN (Homo sapiens)	5 / 10	TYR B 90 ASP B 85 VAL B 111 GLN B 83 LEU B 63	None	1.11A	5fxfB-6b0eB: undetectable	5fxfB-6b0eB: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_A_SAMA401_1 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	6b0e	1260 ANTIBODY, HEAVY CHAIN (Homo sapiens)	3 / 3	ASP B 95 ARG B 96 ASP B 58	None	0.57A	5zvgA-6b0eB: undetectable	5zvgA-6b0eB: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_B_SAMB401_1 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	6b0e	1260 ANTIBODY, HEAVY CHAIN (Homo sapiens)	3 / 3	ASP B 95 ARG B 96 ASP B 58	None	0.58A	5zvgB-6b0eB: undetectable	5zvgB-6b0eB: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DEB_B_MTXB303_1 (BIFUNCTIONAL PROTEIN FOLD)	6b0e	1260 ANTIBODY, HEAVY CHAIN (Homo sapiens)	4 / 5	TYR B 59 GLN B 64 GLY B 97 ILE B 51	None	1.44A	6debB-6b0eB: undetectable	6debB-6b0eB: 15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G31_C_ZOLC401_0 (GERANYLGERANYL PYROPHOSPHATE SYNTHASE)	6b0e	1260 ANTIBODY, HEAVY CHAIN (Homo sapiens)	4 / 5	ASP B 86 ASP B 85 ARG B 38 GLN B 83	None	1.27A	6g31C-6b0eB: undetectable	6g31C-6b0eB: 14.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3G4L_D_ROFD904_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","6b0e","1260 ANTIBODY, HEAVY CHAIN","Homo sapiens",3,"ASN B  76;MET B  69;PHE B  34","None","1.04A","3g4lD-6b0eB:undetectable","3g4lD-6b0eB:16.79"],["4FP9_D_SAMD401_1","METHYLTRANSFERASE NSUN4","6b0e","1260 ANTIBODY, HEAVY CHAIN","Homo sapiens",3,"ASP B  95;ARG B  96;ASP B  58","None","0.76A","4fp9D-6b0eB:undetectable","4fp9D-6b0eB:21.39"],["4FZV_A_SAMA401_1","PUTATIVE METHYLTRANSFERASE NSUN4","6b0e","1260 ANTIBODY, HEAVY CHAIN","Homo sapiens",3,"ASP B  95;ARG B  96;ASP B  58","None","0.73A","4fzvA-6b0eB:undetectable","4fzvA-6b0eB:21.17"],["5FXF_B_BEZB601_0","EUGENOL OXIDASE","6b0e","1260 ANTIBODY, HEAVY CHAIN","Homo sapiens",5,"TYR B  90;ASP B  85;VAL B 111;GLN B  83;LEU B  63","None","1.11A","5fxfB-6b0eB:undetectable","5fxfB-6b0eB:18.11"],["5ZVG_A_SAMA401_1","389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN","6b0e","1260 ANTIBODY, HEAVY CHAIN","Homo sapiens",3,"ASP B  95;ARG B  96;ASP B  58","None","0.57A","5zvgA-6b0eB:undetectable","5zvgA-6b0eB:18.89"],["5ZVG_B_SAMB401_1","389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN","6b0e","1260 ANTIBODY, HEAVY CHAIN","Homo sapiens",3,"ASP B  95;ARG B  96;ASP B  58","None","0.58A","5zvgB-6b0eB:undetectable","5zvgB-6b0eB:18.89"],["6DEB_B_MTXB303_1","BIFUNCTIONAL PROTEIN FOLD","6b0e","1260 ANTIBODY, HEAVY CHAIN","Homo sapiens",4,"TYR B  59;GLN B  64;GLY B  97;ILE B  51","None","1.44A","6debB-6b0eB:undetectable","6debB-6b0eB:15.45"],["6G31_C_ZOLC401_0","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","6b0e","1260 ANTIBODY, HEAVY CHAIN","Homo sapiens",4,"ASP B  86;ASP B  85;ARG B  38;GLN B  83","None","1.27A","6g31C-6b0eB:undetectable","6g31C-6b0eB:14.10"]]