SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b0i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 6b0i KINESIN-LIKE PROTEIN
KLP10A
(Drosophila
melanogaster) 		3 / 3 LYS K 306
ARG K 330
LYS K 580
 None
 1.27A 3okxA-6b0iK:
undetectable		 3okxA-6b0iK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6b0i KINESIN-LIKE PROTEIN
KLP10A
(Drosophila
melanogaster) 		3 / 3 SER K 478
GLY K 479
GLN K 480
 None
 0.58A 3v4tH-6b0iK:
undetectable		 3v4tH-6b0iK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 6b0i KINESIN-LIKE PROTEIN
KLP10A
(Drosophila
melanogaster) 		4 / 6 GLN K 568
ASP K 572
GLN K 448
GLU K 577
 None
 1.38A 4azvA-6b0iK:
undetectable		 4azvA-6b0iK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 6b0i KINESIN-LIKE PROTEIN
KLP10A
(Drosophila
melanogaster) 		5 / 11 ALA K 544
SER K 541
THR K 581
ILE K 513
SER K 511
 None
 1.32A 4bb2A-6b0iK:
undetectable
4bb2B-6b0iK:
undetectable		 4bb2A-6b0iK:
12.57
4bb2B-6b0iK:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 6b0i KINESIN-LIKE PROTEIN
KLP10A
(Drosophila
melanogaster) 		4 / 6 GLY K 371
THR K 370
SER K 588
HIS K 596
 None
 0.98A 5ewuB-6b0iK:
undetectable		 5ewuB-6b0iK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 6b0i KINESIN-LIKE PROTEIN
KLP10A
(Drosophila
melanogaster) 		5 / 12 PRO K 287
GLY K 371
GLY K 373
ILE K 587
ASN K 484
 None
 1.14A 5fa8A-6b0iK:
undetectable		 5fa8A-6b0iK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 6b0i KINESIN-LIKE PROTEIN
KLP10A
(Drosophila
melanogaster) 		5 / 12 ALA K 585
GLY K 373
ASP K 605
ALA K 604
PHE K 331
 None
 1.34A 5zvgA-6b0iK:
undetectable		 5zvgA-6b0iK:
undetectable