SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b0k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		5 / 12 PHE A  77
SER A 393
PHE A 472
PHE A 455
HIS A  92
 9RN  A 504 ( 3.6A)
None
None
None
CL  A 510 ( 4.7A)
 1.26A 1q23D-6b0kA:
undetectable
1q23E-6b0kA:
undetectable		 1q23D-6b0kA:
15.85
1q23E-6b0kA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		5 / 12 PRO A  80
GLY A  79
ASN A  99
ASP A 112
SER A 453
 None
None
G4S  A 503 ( 3.4A)
None
None
 1.15A 2b9eA-6b0kA:
undetectable		 2b9eA-6b0kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 6 ALA A 385
TYR A  72
ILE A 397
ILE A 383
 None
 1.25A 2dcfA-6b0kA:
undetectable		 2dcfA-6b0kA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 6 ARG A 254
GLY A 299
PRO A 232
THR A 234
 None
None
None
9RN  A 502 ( 3.3A)
 1.06A 2m2oB-6b0kA:
undetectable		 2m2oB-6b0kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 4 ALA A 370
VAL A 339
PHE A 371
THR A 347
 None
 1.31A 2pkkA-6b0kA:
undetectable		 2pkkA-6b0kA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		5 / 12 LEU A  34
PHE A 348
LEU A  85
SER A  81
VAL A 339
 None
 1.26A 2pnjB-6b0kA:
undetectable		 2pnjB-6b0kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		5 / 12 LEU A  34
PHE A 348
LEU A  85
ILE A 286
SER A  81
 None
 1.16A 2po5A-6b0kA:
undetectable		 2po5A-6b0kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		3 / 3 LYS A 270
ARG A 207
VAL A 210
 None
 0.88A 2r2vC-6b0kA:
undetectable
2r2vD-6b0kA:
undetectable		 2r2vC-6b0kA:
undetectable
2r2vD-6b0kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 TYR A 226
ARG A  82
TRP A 133
ARG A 146
 None
 1.46A 2vxaA-6b0kA:
undetectable
2vxaC-6b0kA:
undetectable
2vxaE-6b0kA:
undetectable		 2vxaA-6b0kA:
17.65
2vxaC-6b0kA:
17.65
2vxaE-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 TYR A 226
TRP A 133
ARG A 146
HIS A 134
 None
None
None
G4S  A 503 ( 4.2A)
 1.45A 2vxaA-6b0kA:
undetectable
2vxaC-6b0kA:
undetectable
2vxaE-6b0kA:
undetectable		 2vxaA-6b0kA:
17.65
2vxaC-6b0kA:
17.65
2vxaE-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 ARG A 146
TYR A 226
ARG A  82
TRP A 133
 None
 1.48A 2vxaA-6b0kA:
undetectable
2vxaB-6b0kA:
undetectable
2vxaK-6b0kA:
undetectable		 2vxaA-6b0kA:
17.65
2vxaB-6b0kA:
17.65
2vxaK-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 ARG A 146
TYR A 226
TRP A 133
HIS A 134
 None
None
None
G4S  A 503 ( 4.2A)
 1.47A 2vxaA-6b0kA:
undetectable
2vxaB-6b0kA:
undetectable
2vxaK-6b0kA:
undetectable		 2vxaA-6b0kA:
17.65
2vxaB-6b0kA:
17.65
2vxaK-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 ARG A 146
TYR A 226
ARG A  82
TRP A 133
 None
 1.46A 2vxaB-6b0kA:
undetectable
2vxaC-6b0kA:
undetectable
2vxaG-6b0kA:
undetectable		 2vxaB-6b0kA:
17.65
2vxaC-6b0kA:
17.65
2vxaG-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 ARG A 146
TYR A 226
TRP A 133
HIS A 134
 None
None
None
G4S  A 503 ( 4.2A)
 1.46A 2vxaB-6b0kA:
undetectable
2vxaC-6b0kA:
undetectable
2vxaG-6b0kA:
undetectable		 2vxaB-6b0kA:
17.65
2vxaC-6b0kA:
17.65
2vxaG-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 ARG A 146
TYR A 226
ARG A  82
TRP A 133
 None
 1.47A 2vxaD-6b0kA:
undetectable
2vxaE-6b0kA:
undetectable
2vxaL-6b0kA:
undetectable		 2vxaD-6b0kA:
17.65
2vxaE-6b0kA:
17.65
2vxaL-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 ARG A 146
TYR A 226
TRP A 133
HIS A 134
 None
None
None
G4S  A 503 ( 4.2A)
 1.48A 2vxaD-6b0kA:
undetectable
2vxaE-6b0kA:
undetectable
2vxaL-6b0kA:
undetectable		 2vxaD-6b0kA:
17.65
2vxaE-6b0kA:
17.65
2vxaL-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 HIS A 134
TYR A 226
TRP A 133
ARG A 146
 G4S  A 503 ( 4.2A)
None
None
None
 1.46A 2vxaD-6b0kA:
undetectable
2vxaJ-6b0kA:
undetectable
2vxaL-6b0kA:
undetectable		 2vxaD-6b0kA:
17.65
2vxaJ-6b0kA:
17.65
2vxaL-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 TYR A 226
ARG A  82
TRP A 133
ARG A 146
 None
 1.45A 2vxaD-6b0kA:
undetectable
2vxaJ-6b0kA:
undetectable
2vxaL-6b0kA:
undetectable		 2vxaD-6b0kA:
17.65
2vxaJ-6b0kA:
17.65
2vxaL-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 5 ILE A 372
PHE A  68
VAL A 268
PHE A 348
 ARG  A 507 (-3.6A)
None
None
None
 1.08A 2ygnA-6b0kA:
undetectable		 2ygnA-6b0kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 7 GLY A  88
ALA A  74
ALA A 341
ILE A  94
 None
 0.76A 3a2qA-6b0kA:
undetectable		 3a2qA-6b0kA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 GLY A 108
PHE A 224
PHE A 115
PHE A 148
 None
 1.05A 3ko0D-6b0kA:
undetectable
3ko0E-6b0kA:
undetectable		 3ko0D-6b0kA:
19.61
3ko0E-6b0kA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 7 GLY A 108
PHE A 224
PHE A 115
PHE A 148
 None
 1.00A 3ko0L-6b0kA:
undetectable
3ko0N-6b0kA:
undetectable		 3ko0L-6b0kA:
19.61
3ko0N-6b0kA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 7 PHE A 115
PHE A 148
GLY A 108
PHE A 224
 None
 1.02A 3ko0R-6b0kA:
undetectable
3ko0T-6b0kA:
undetectable		 3ko0R-6b0kA:
19.61
3ko0T-6b0kA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		5 / 11 ASP A 291
HIS A  75
VAL A  73
GLY A 308
PRO A 320
 CA  A 501 (-2.4A)
None
None
None
None
 0.97A 3sm2B-6b0kA:
undetectable		 3sm2B-6b0kA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		5 / 12 ILE A  35
ALA A  37
ALA A 231
HIS A 324
LEU A 322
 None
 1.12A 4nqaH-6b0kA:
undetectable		 4nqaH-6b0kA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 7 TYR A 229
GLY A 267
SER A 206
LEU A 271
 None
 1.01A 5bphB-6b0kA:
undetectable		 5bphB-6b0kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 5 SER A 290
GLY A 158
THR A 102
GLU A 183
 None
G4S  A 503 ( 4.5A)
None
None
 1.21A 5btiA-6b0kA:
undetectable
5btiB-6b0kA:
undetectable		 5btiA-6b0kA:
9.54
5btiB-6b0kA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 ILE A  53
ASP A  52
GLY A 299
LEU A 296
 None
 1.03A 5hwaA-6b0kA:
undetectable		 5hwaA-6b0kA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		3 / 3 ARG A 398
PRO A 338
ASN A 376
 None
 0.93A 5jwaA-6b0kA:
undetectable
5jwaH-6b0kA:
undetectable		 5jwaA-6b0kA:
undetectable
5jwaH-6b0kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		5 / 11 ARG A 318
LEU A 305
ASN A 302
ALA A 300
ILE A  53
 None
 1.10A 5kr2B-6b0kA:
undetectable		 5kr2B-6b0kA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		3 / 3 THR A 186
HIS A 159
ASN A 160
 None
 0.89A 5n4tA-6b0kA:
undetectable		 5n4tA-6b0kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 6 PHE A 323
GLY A  65
THR A  66
LYS A 333
 None
 0.98A 5x24A-6b0kA:
undetectable		 5x24A-6b0kA:
11.06