SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  63
MET D  80
MET D  69
ALA D  78
None
1.25A 1linA-6b0nD:
undetectable
1linA-6b0nD:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 VAL D 111
ARG D  66
VAL D  18
PHE D  82
None
1.26A 1zzrA-6b0nD:
undetectable
1zzrB-6b0nD:
undetectable
1zzrA-6b0nD:
12.81
1zzrB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.27A 1zzuA-6b0nD:
undetectable
1zzuB-6b0nD:
undetectable
1zzuA-6b0nD:
12.81
1zzuB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
5 / 12 LEU G 349
ILE G 272
PHE G 288
GLY G 451
LEU G 454
None
1.25A 2bxeB-6b0nG:
undetectable
2bxeB-6b0nG:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 5 SER D 177
VAL D 169
SER D 179
VAL D 142
None
1.24A 2j9cA-6b0nD:
undetectable
2j9cB-6b0nD:
undetectable
2j9cC-6b0nD:
undetectable
2j9cA-6b0nD:
undetectable
2j9cB-6b0nD:
undetectable
2j9cC-6b0nD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
3 / 3 VAL G 506
GLU G 657
GLU G 654
None
0.80A 2nv4A-6b0nG:
undetectable
2nv4A-6b0nG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)
6b0n PGV19 FAB HEAVY
CHAIN
PGV19 LIGHT CHAIN

(Homo
sapiens;
Homo
sapiens)
5 / 12 ILE E  48
TYR E  86
LEU E  47
GLN D  39
LEU D  45
None
1.39A 2rctA-6b0nE:
undetectable
2rctA-6b0nE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)
6b0n PGV19 FAB HEAVY
CHAIN
PGV19 LIGHT CHAIN

(Homo
sapiens)
4 / 6 VAL E  39
GLN D  39
GLY E 100
LEU E   4
None
0.98A 3bjwE-6b0nE:
undetectable
3bjwE-6b0nE:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)
6b0n PGV19 FAB HEAVY
CHAIN
PGV19 LIGHT CHAIN

(Homo
sapiens)
4 / 7 VAL E  39
GLN D  39
GLY E 100
LEU E   4
None
0.90A 3bjwF-6b0nE:
undetectable
3bjwF-6b0nE:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
4 / 4 THR G  37
VAL G  42
GLY G 531
THR G 529
None
1.04A 3cflA-6b0nG:
undetectable
3cflA-6b0nG:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.29A 3dqrA-6b0nD:
undetectable
3dqrB-6b0nD:
undetectable
3dqrA-6b0nD:
12.81
3dqrB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
4 / 4 PRO G 470
THR G 455
GLY G 459
THR G 461
None
1.08A 3ib1A-6b0nG:
undetectable
3ib1A-6b0nG:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.29A 3jx2A-6b0nD:
undetectable
3jx2B-6b0nD:
undetectable
3jx2A-6b0nD:
12.81
3jx2B-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.27A 3jx3A-6b0nD:
undetectable
3jx3B-6b0nD:
undetectable
3jx3A-6b0nD:
12.81
3jx3B-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 6 VAL D 111
ARG D  66
VAL D  18
PHE D  82
None
1.29A 3jx4A-6b0nD:
undetectable
3jx4B-6b0nD:
undetectable
3jx4A-6b0nD:
12.81
3jx4B-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.29A 3jx4A-6b0nD:
undetectable
3jx4B-6b0nD:
undetectable
3jx4A-6b0nD:
12.81
3jx4B-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.31A 3jx5A-6b0nD:
undetectable
3jx5B-6b0nD:
undetectable
3jx5A-6b0nD:
12.81
3jx5B-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.27A 3jx6A-6b0nD:
undetectable
3jx6B-6b0nD:
undetectable
3jx6A-6b0nD:
12.81
3jx6B-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
5 / 12 ASN G 363
LEU G 452
GLY G 471
GLY G 472
ILE G 449
NAG  G1363 (-2.5A)
None
None
None
None
1.04A 3nk7A-6b0nG:
undetectable
3nk7A-6b0nG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
5 / 12 ASN G 363
LEU G 452
GLY G 471
GLY G 472
ILE G 449
NAG  G1363 (-2.5A)
None
None
None
None
1.00A 3nk7B-6b0nG:
undetectable
3nk7B-6b0nG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.29A 3nlpA-6b0nD:
undetectable
3nlpB-6b0nD:
undetectable
3nlpA-6b0nD:
12.81
3nlpB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.26A 3nlqA-6b0nD:
undetectable
3nlqB-6b0nD:
undetectable
3nlqA-6b0nD:
12.81
3nlqB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 VAL D 111
ARG D  66
VAL D  18
PHE D  82
None
1.26A 3nlrA-6b0nD:
undetectable
3nlrB-6b0nD:
undetectable
3nlrA-6b0nD:
12.81
3nlrB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
4 / 6 CYH G 604
THR G 605
CYH G 598
GLY G 597
None
1.14A 3w9tE-6b0nG:
undetectable
3w9tE-6b0nG:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
4 / 6 PRO G  43
GLY G  41
LEU G 544
ASN G 543
None
0.99A 3zqtA-6b0nG:
undetectable
3zqtA-6b0nG:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
4 / 6 ARG G 151
ASP G 180
GLN G 422
GLU G 370
NAG  G1133 ( 4.0A)
None
None
None
0.96A 4azvA-6b0nG:
undetectable
4azvA-6b0nG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.26A 4cx3A-6b0nD:
undetectable
4cx3B-6b0nD:
undetectable
4cx3A-6b0nD:
12.81
4cx3B-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.25A 4cx4A-6b0nD:
undetectable
4cx4B-6b0nD:
undetectable
4cx4A-6b0nD:
12.81
4cx4B-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)
6b0n PGV19 LIGHT CHAIN
(Homo
sapiens)
4 / 6 LEU E 132
ALA E 130
LEU E 178
THR E 181
None
1.12A 4d7bB-6b0nE:
3.3
4d7bB-6b0nE:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
5 / 12 PHE G 391
ASN G 332
VAL G 292
ILE G 449
LEU G 452
None
NAG  G1331 ( 2.0A)
None
None
None
1.26A 4k39A-6b0nG:
undetectable
4k39A-6b0nG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
5 / 11 ILE G 215
ALA G  55
LEU G  52
LEU G 483
ILE G 251
None
1.09A 4p66A-6b0nG:
undetectable
4p66A-6b0nG:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
5 / 12 GLY G 312
VAL G 120
LEU G 122
SER G 306
ILE G 307
None
1.18A 4pd9A-6b0nG:
undetectable
4pd9A-6b0nG:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 6 VAL D 111
ARG D  66
VAL D  18
PHE D  82
None
1.28A 5addA-6b0nD:
undetectable
5addB-6b0nD:
undetectable
5addA-6b0nD:
12.81
5addB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.25A 5addA-6b0nD:
undetectable
5addB-6b0nD:
undetectable
5addA-6b0nD:
12.81
5addB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 6 VAL D 111
ARG D  66
VAL D  18
PHE D  82
None
1.30A 5adeA-6b0nD:
undetectable
5adeB-6b0nD:
undetectable
5adeA-6b0nD:
12.81
5adeB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.29A 5adeA-6b0nD:
undetectable
5adeB-6b0nD:
undetectable
5adeA-6b0nD:
12.81
5adeB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 VAL D 111
ARG D  66
VAL D  18
PHE D  82
None
1.29A 5g0pA-6b0nD:
undetectable
5g0pB-6b0nD:
undetectable
5g0pA-6b0nD:
12.81
5g0pB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6b0n PGV19 FAB HEAVY
CHAIN

(Homo
sapiens)
4 / 7 PHE D  82
VAL D 111
ARG D  66
VAL D  18
None
1.27A 5g0pA-6b0nD:
undetectable
5g0pB-6b0nD:
undetectable
5g0pA-6b0nD:
12.81
5g0pB-6b0nD:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
4 / 8 LEU G 259
PHE G 391
LEU G 416
ILE G 414
None
0.90A 5mzjA-6b0nG:
undetectable
5mzjA-6b0nG:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus
1)
4 / 6 PHE G 468
LEU G 452
ARG G 469
GLY G 471
None
1.15A 5o4yA-6b0nG:
undetectable
5o4yA-6b0nG:
undetectable