SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b1p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 6b1p GLUTAMATE--TRNA
LIGASE 1
(Helicobacter
pylori) 		5 / 12 GLU A 234
LEU A 265
PHE A 264
LEU A 261
TYR A 256
 None
 1.29A 2mjiA-6b1pA:
undetectable		 2mjiA-6b1pA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 6b1p GLUTAMATE--TRNA
LIGASE 1
(Helicobacter
pylori) 		5 / 11 VAL A 141
ALA A 174
GLY A 178
TYR A  86
PHE A 184
 None
 1.35A 3qxyB-6b1pA:
undetectable
3qxyQ-6b1pA:
undetectable		 3qxyB-6b1pA:
23.15
3qxyQ-6b1pA:
2.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 6b1p GLUTAMATE--TRNA
LIGASE 1
(Helicobacter
pylori) 		3 / 3 MET A 230
HIS A 204
GLY A  19
 None
 0.87A 5gwzB-6b1pA:
undetectable		 5gwzB-6b1pA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 6b1p GLUTAMATE--TRNA
LIGASE 1
(Helicobacter
pylori) 		3 / 3 MET A 230
HIS A 204
GLY A  20
 None
 0.79A 5gwzB-6b1pA:
undetectable		 5gwzB-6b1pA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 6b1p GLUTAMATE--TRNA
LIGASE 1
(Helicobacter
pylori) 		4 / 8 LEU A 261
ILE A  18
PHE A 264
PHE A 299
 None
 1.04A 5m0oC-6b1pA:
undetectable		 5m0oC-6b1pA:
21.84