SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		4 / 6 LEU A 114
GLU A 113
THR A 157
TYR A 130
 None
 1.17A 1qvuA-6b1zA:
undetectable		 1qvuA-6b1zA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		4 / 8 PHE A 277
ASN A 276
GLU A 292
GLY A 288
 None
 1.09A 1ykiA-6b1zA:
undetectable
1ykiB-6b1zA:
undetectable		 1ykiA-6b1zA:
16.67
1ykiB-6b1zA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		4 / 8 PHE A 277
ASN A 276
GLU A 292
GLY A 288
 None
 1.08A 1ykiC-6b1zA:
undetectable
1ykiD-6b1zA:
undetectable		 1ykiC-6b1zA:
16.67
1ykiD-6b1zA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		3 / 3 ASN A 136
ARG A 135
ASP A 102
 None
 1.00A 2qe6A-6b1zA:
undetectable		 2qe6A-6b1zA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		5 / 10 ILE A 161
LEU A 230
ILE A  98
ILE A 207
PHE A 204
 None
 1.17A 2w9sC-6b1zA:
undetectable		 2w9sC-6b1zA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		4 / 6 ALA A  61
LEU A  62
ALA A  24
THR A  23
 None
None
None
FMT  A 608 ( 4.4A)
 0.87A 3b6hA-6b1zA:
undetectable		 3b6hA-6b1zA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		4 / 6 ALA A  61
LEU A  62
ALA A  24
THR A  23
 None
None
None
FMT  A 608 ( 4.4A)
 0.90A 3b6hB-6b1zA:
undetectable		 3b6hB-6b1zA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		5 / 12 ILE A 486
LEU A 482
ASP A 481
PHE A 439
SER A 447
 None
None
FMT  A 614 (-3.6A)
None
None
 1.19A 3ko0K-6b1zA:
undetectable
3ko0L-6b1zA:
undetectable
3ko0S-6b1zA:
undetectable
3ko0T-6b1zA:
undetectable		 3ko0K-6b1zA:
10.96
3ko0L-6b1zA:
10.96
3ko0S-6b1zA:
10.96
3ko0T-6b1zA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		3 / 3 HIS A 405
SER A 409
GLU A 408
 None
 0.76A 3s8pA-6b1zA:
undetectable		 3s8pA-6b1zA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		4 / 7 THR A 134
ASN A 140
TYR A 105
PHE A 128
 None
 1.34A 4awuA-6b1zA:
undetectable		 4awuA-6b1zA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		3 / 3 ILE A 219
ASP A 175
ARG A  22
 None
None
EDO  A 617 ( 3.7A)
 0.77A 4pstA-6b1zA:
undetectable		 4pstA-6b1zA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		4 / 7 ILE A 207
LEU A 230
LEU A 193
ILE A  98
 None
 0.73A 4rmjA-6b1zA:
undetectable		 4rmjA-6b1zA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		5 / 11 ALA A 418
VAL A 479
ASP A 478
GLY A 472
GLY A 476
 None
None
FMT  A 614 (-3.8A)
None
None
 1.19A 4xp4A-6b1zA:
undetectable		 4xp4A-6b1zA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		5 / 12 ILE A 219
VAL A 218
GLY A 221
VAL A 183
LEU A 173
 None
 1.02A 5ergB-6b1zA:
2.2		 5ergB-6b1zA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 6b1z GLUTAMATE--TRNA
LIGASE
(Elizabethkingia
anophelis) 		4 / 5 THR A 185
ASN A 184
ASP A 168
LEU A 167
 None
 1.32A 5m0iB-6b1zA:
undetectable		 5m0iB-6b1zA:
19.72