SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b20'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOF_A_PNNA1312_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 6b20 GUANINE
NUCLEOTIDE-BINDING
PROTEIN
G(I)/G(S)/G(T)
SUBUNIT BETA-1
(Bos
taurus) 		5 / 11 ASP A 163
HIS A 142
VAL A 158
SER A 201
VAL A 187
 None
 1.46A 1uofA-6b20A:
undetectable		 1uofA-6b20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 6b20 GUANINE
NUCLEOTIDE-BINDING
PROTEIN
G(I)/G(S)/G(T)
SUBUNIT BETA-1
(Bos
taurus) 		5 / 12 LEU A 168
PHE A 180
LEU A 152
LEU A 192
ALA A 193
 None
 1.22A 2bxpA-6b20A:
undetectable		 2bxpA-6b20A:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 6b20 GUANINE
NUCLEOTIDE-BINDING
PROTEIN
G(I)/G(S)/G(T)
SUBUNIT BETA-1
(Bos
taurus) 		4 / 8 SER A 245
ASP A 247
SER A 227
ASN A 230
 None
 1.12A 2cmlD-6b20A:
8.9		 2cmlD-6b20A:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 6b20 GUANINE
NUCLEOTIDE-BINDING
PROTEIN
G(I)/G(S)/G(T)
SUBUNIT BETA-1
(Bos
taurus) 		4 / 7 ASP A 154
PHE A 151
PRO A 107
THR A  65
 None
 1.38A 2q6kA-6b20A:
undetectable		 2q6kA-6b20A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 6b20 GUANINE
NUCLEOTIDE-BINDING
PROTEIN
G(I)/G(S)/G(T)
SUBUNIT BETA-1
(Bos
taurus) 		4 / 6 ASP A 154
PHE A 151
PRO A 107
THR A  65
 None
 1.35A 2q6oB-6b20A:
undetectable		 2q6oB-6b20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 6b20 GUANINE
NUCLEOTIDE-BINDING
PROTEIN
G(I)/G(S)/G(T)
SUBUNIT BETA-1
(Bos
taurus) 		4 / 5 LEU A  51
THR A  87
THR A 329
HIS A 311
 None
 1.24A 2zj0B-6b20A:
undetectable		 2zj0B-6b20A:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 6b20 GUANINE
NUCLEOTIDE-BINDING
PROTEIN
G(I)/G(S)/G(T)
SUBUNIT BETA-1
(Bos
taurus) 		3 / 3 SER A 265
ASP A 267
ASP A 247
 None
 0.90A 3iv6C-6b20A:
undetectable		 3iv6C-6b20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 6b20 GUANINE
NUCLEOTIDE-BINDING
PROTEIN
G(I)/G(S)/G(T)
SUBUNIT BETA-1
(Bos
taurus) 		5 / 10 ILE A 229
LEU A 285
PRO A 236
ILE A 232
THR A 249
 None
 1.12A 4g8zX-6b20A:
undetectable		 4g8zX-6b20A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 6b20 GUANINE
NUCLEOTIDE-BINDING
PROTEIN
G(I)/G(S)/G(T)
SUBUNIT BETA-1
(Bos
taurus) 		5 / 12 SER A 201
GLY A 202
ALA A 203
ASP A 205
THR A 184
 None
 1.25A 4xt8A-6b20A:
undetectable		 4xt8A-6b20A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 6b20 GUANINE
NUCLEOTIDE-BINDING
PROTEIN
G(I)/G(S)/G(T)
SUBUNIT BETA-1
(Bos
taurus) 		5 / 12 ASP A 291
ALA A 287
SER A 275
ARG A  42
LEU A 308
 None
 1.50A 5m54B-6b20A:
undetectable		 5m54B-6b20A:
10.63