SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b23'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 6b23 MAJOR HEAD PROTEIN
(Staphylococcus
virus
80alpha) 		3 / 3 TRP A  98
ALA A 293
VAL A  99
 None
 0.90A 1c4dC-6b23A:
undetectable
1c4dD-6b23A:
undetectable		 1c4dC-6b23A:
6.79
1c4dD-6b23A:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6b23 MAJOR HEAD PROTEIN
(Staphylococcus
virus
80alpha) 		3 / 3 LEU A  39
ARG A 104
ASN A 100
 None
 0.75A 3qxvD-6b23A:
undetectable		 3qxvD-6b23A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 6b23 MAJOR HEAD PROTEIN
(Staphylococcus
virus
80alpha) 		5 / 11 ILE A  47
THR A  44
LEU A  39
THR A  38
LEU A 291
 None
 1.15A 4g1bB-6b23A:
undetectable		 4g1bB-6b23A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 6b23 MAJOR HEAD PROTEIN
(Staphylococcus
virus
80alpha) 		5 / 12 ILE A  47
THR A  44
LEU A  39
THR A  38
LEU A 291
 None
 1.13A 4g1bD-6b23A:
undetectable		 4g1bD-6b23A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6b23 MAJOR HEAD PROTEIN
(Staphylococcus
virus
80alpha) 		4 / 5 ILE A  47
LEU A  39
GLU A 128
VAL A  29
 None
 1.01A 4nkxB-6b23A:
undetectable		 4nkxB-6b23A:
21.81