SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b2v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 6b2v SORB
(Sorangium
cellulosum) 		4 / 8 LEU A 261
PRO A 220
VAL A 188
GLY A 185
 None
 1.02A 1hrkA-6b2vA:
undetectable		 1hrkA-6b2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 6b2v SORB
(Sorangium
cellulosum) 		4 / 7 THR A 262
ALA A 101
TYR A  91
LEU A  43
 None
 1.05A 2hzqA-6b2vA:
undetectable		 2hzqA-6b2vA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 6b2v SORB
(Sorangium
cellulosum) 		5 / 9 ALA A  41
GLY A 185
ASP A 181
LEU A 184
ASN A 183
 None
 1.18A 3wdmA-6b2vA:
undetectable		 3wdmA-6b2vA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 6b2v SORB
(Sorangium
cellulosum) 		5 / 9 ALA A  41
GLY A 185
ASP A 181
LEU A 184
ASN A 183
 None
 1.19A 3wdmC-6b2vA:
undetectable		 3wdmC-6b2vA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 6b2v SORB
(Sorangium
cellulosum) 		5 / 12 TYR A  42
ALA A  46
VAL A  99
HIS A 100
ILE A  66
 None
 1.04A 4rvgA-6b2vA:
undetectable		 4rvgA-6b2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 6b2v SORB
(Sorangium
cellulosum) 		4 / 8 VAL A 188
GLY A 260
LEU A 211
THR A 262
 None
 0.81A 5sxqB-6b2vA:
undetectable		 5sxqB-6b2vA:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 6b2v SORB
(Sorangium
cellulosum) 		4 / 8 VAL A 188
GLY A 260
LEU A 211
THR A 262
 None
 0.84A 5syjA-6b2vA:
undetectable		 5syjA-6b2vA:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_F_EVPF1301_1
()		 6b2v SORB
(Sorangium
cellulosum) 		4 / 4 GLY A 260
ASP A 244
ARG A 230
MET A 142
 None
 1.36A 5zrfA-6b2vA:
undetectable		 5zrfA-6b2vA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 6b2v SORB
(Sorangium
cellulosum) 		4 / 4 LEU A 180
ASP A 219
PRO A 220
ARG A 221
 None
 1.12A 6fgdA-6b2vA:
undetectable		 6fgdA-6b2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 6b2v SORB
(Sorangium
cellulosum) 		4 / 4 LEU A 184
ASP A 219
PRO A 220
ARG A 221
 None
 1.26A 6fgdA-6b2vA:
undetectable		 6fgdA-6b2vA:
undetectable