SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b2w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
3 / 3 ASP A 197
PHE A 190
ASN A 310
None
0.80A 1sg9B-6b2wA:
undetectable
1sg9B-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
5 / 9 LEU A 272
ILE A 207
PHE A 265
LEU A 245
ILE A 285
None
1.16A 2f78A-6b2wA:
undetectable
2f78A-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
5 / 9 LEU A 272
ILE A 207
PHE A 265
LEU A 245
ILE A 285
None
1.20A 2f78B-6b2wA:
undetectable
2f78B-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
5 / 9 LEU A 272
ILE A 207
PHE A 265
LEU A 245
ILE A 285
None
1.16A 2f7aB-6b2wA:
undetectable
2f7aB-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 8 HIS A 199
ASP A 201
SER A 316
ASP A 194
AG2  A 401 (-3.7A)
AG2  A 401 ( 4.7A)
None
None
1.22A 2obvA-6b2wA:
undetectable
2obvA-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 7 ASP A 222
ILE A 247
GLN A 229
ARG A 257
None
1.04A 2qqcA-6b2wA:
undetectable
2qqcF-6b2wA:
undetectable
2qqcA-6b2wA:
21.33
2qqcF-6b2wA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 7 ASP A 222
ILE A 247
GLN A 229
ARG A 257
None
1.01A 2qqcG-6b2wA:
undetectable
2qqcJ-6b2wA:
undetectable
2qqcG-6b2wA:
21.33
2qqcJ-6b2wA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 6 PHE A 178
PHE A 143
GLY A 138
GLY A 139
None
0.95A 2qr2A-6b2wA:
undetectable
2qr2B-6b2wA:
undetectable
2qr2A-6b2wA:
17.39
2qr2B-6b2wA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 5 GLY A 138
GLY A 139
PHE A 178
PHE A 143
None
0.94A 2qr2A-6b2wA:
undetectable
2qr2B-6b2wA:
undetectable
2qr2A-6b2wA:
17.39
2qr2B-6b2wA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 8 ILE A 191
TYR A 277
TYR A 262
CYH A 215
None
1.06A 2xz5C-6b2wA:
undetectable
2xz5D-6b2wA:
undetectable
2xz5C-6b2wA:
undetectable
2xz5D-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 8 ILE A 191
TYR A 277
TYR A 262
CYH A 215
None
1.21A 2xz5C-6b2wA:
undetectable
2xz5D-6b2wA:
undetectable
2xz5C-6b2wA:
undetectable
2xz5D-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
5 / 12 ILE A 298
ALA A 292
LEU A 243
GLU A 283
PRO A 246
None
1.28A 3eigA-6b2wA:
undetectable
3eigA-6b2wA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
5 / 12 ILE A 298
ALA A 292
LEU A 243
PRO A 246
ASN A 281
None
1.19A 3eigA-6b2wA:
undetectable
3eigA-6b2wA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_1
(O-METHYLTRANSFERASE)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 4 ASP A  77
SER A 110
PHE A 101
SER A 315
AG2  A 401 ( 4.7A)
None
None
AG2  A 401 (-3.1A)
1.38A 3i5uA-6b2wA:
undetectable
3i5uA-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 8 ARG A  81
VAL A  43
GLN A  11
ARG A 205
None
1.18A 3uy4A-6b2wA:
undetectable
3uy4A-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
5 / 12 VAL A 132
ILE A  86
LEU A 156
ILE A 183
LEU A 180
None
0.98A 3w67D-6b2wA:
1.2
3w67D-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 8 TYR A 277
TYR A 262
CYH A 215
ILE A 191
None
0.94A 4aftD-6b2wA:
undetectable
4aftE-6b2wA:
undetectable
4aftD-6b2wA:
17.37
4aftE-6b2wA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 8 TYR A 277
TYR A 262
CYH A 215
ILE A 191
None
0.96A 4bqtC-6b2wA:
undetectable
4bqtD-6b2wA:
undetectable
4bqtC-6b2wA:
undetectable
4bqtD-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 8 TYR A 277
TYR A 262
CYH A 215
ILE A 191
None
1.32A 4bqtC-6b2wA:
undetectable
4bqtD-6b2wA:
undetectable
4bqtC-6b2wA:
undetectable
4bqtD-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
5 / 10 GLY A 138
GLY A 139
ASN A 117
PHE A 178
PHE A 143
None
None
K  A 402 ( 4.8A)
None
None
1.25A 4fgkA-6b2wA:
undetectable
4fgkB-6b2wA:
undetectable
4fgkA-6b2wA:
undetectable
4fgkB-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
5 / 12 GLU A 234
THR A 238
ILE A 184
LEU A 150
ILE A 212
None
0.87A 4i13A-6b2wA:
undetectable
4i13A-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 6 ARG A 205
ALA A 213
ASP A 142
LEU A 289
None
1.15A 4ot2A-6b2wA:
undetectable
4ot2A-6b2wA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_A_EF2A151_1
(CEREBLON ISOFORM 4)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 7 ASN A 144
PHE A 143
TRP A   8
PHE A 267
None
1.27A 4v32A-6b2wA:
undetectable
4v32A-6b2wA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
5 / 12 THR A 202
ALA A 263
LEU A 245
HIS A 224
LEU A 228
None
1.30A 4xi3D-6b2wA:
undetectable
4xi3D-6b2wA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 5 GLU A 176
THR A 151
HIS A 199
LEU A 136
None
None
AG2  A 401 (-3.7A)
None
1.26A 5axaA-6b2wA:
undetectable
5axaA-6b2wA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 5 GLU A 176
THR A 151
HIS A 199
LEU A 136
None
None
AG2  A 401 (-3.7A)
None
1.28A 5axaC-6b2wA:
undetectable
5axaC-6b2wA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 6 ASP A 194
TYR A 277
PRO A 248
LEU A 251
None
1.16A 5bmvB-6b2wA:
undetectable
5bmvB-6b2wA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 6 LEU A 289
CYH A 215
HIS A 214
LEU A 245
None
1.17A 5hpuC-6b2wA:
undetectable
5hpuD-6b2wA:
undetectable
5hpuC-6b2wA:
undetectable
5hpuD-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_B_95EB401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 4 TRP A  79
TRP A 104
ASP A  82
SER A 316
AG2  A 401 (-3.6A)
AG2  A 401 (-4.4A)
AG2  A 401 (-3.4A)
None
1.46A 5nr3B-6b2wA:
0.0
5nr3B-6b2wA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
5 / 12 VAL A 132
ASP A  98
LEU A 156
PHE A 178
GLY A  84
None
K  A 402 (-3.1A)
None
None
None
1.27A 5ogcB-6b2wA:
undetectable
5ogcB-6b2wA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 4 GLY A 259
ARG A 256
ASN A 310
LEU A 307
None
1.31A 6b58A-6b2wA:
undetectable
6b58A-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 4 GLY A 311
ARG A 256
ASN A 310
LEU A 307
AG2  A 401 ( 4.1A)
None
None
None
1.36A 6b58A-6b2wA:
undetectable
6b58A-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA502_0
(CANAVALIN)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 4 GLY A 147
LYS A 181
GLN A 182
ASN A 144
None
1.02A 6cb4A-6b2wA:
0.0
6cb4A-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni)
4 / 8 HIS A 199
ASP A 201
SER A 316
ASP A 194
AG2  A 401 (-3.7A)
AG2  A 401 ( 4.7A)
None
None
1.22A 6fcbA-6b2wA:
undetectable
6fcbA-6b2wA:
undetectable