SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 6b3j GLUCAGON-LIKE
PEPTIDE 1 RECEPTOR
(Homo
sapiens) 		4 / 7 VAL R 332
LEU R 349
THR R 353
LEU R 356
 None
 0.89A 1jgsA-6b3jR:
undetectable		 1jgsA-6b3jR:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6b3j GLUCAGON-LIKE
PEPTIDE 1 RECEPTOR
(Homo
sapiens) 		4 / 8 PHE R 321
ASN R 320
GLU R 247
GLY R 248
 None
 0.91A 1ykiA-6b3jR:
undetectable
1ykiB-6b3jR:
undetectable		 1ykiA-6b3jR:
13.82
1ykiB-6b3jR:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6b3j GLUCAGON-LIKE
PEPTIDE 1 RECEPTOR
(Homo
sapiens) 		4 / 8 PHE R 321
ASN R 320
GLU R 247
GLY R 248
 None
 0.88A 1ykiA-6b3jR:
undetectable
1ykiB-6b3jR:
undetectable		 1ykiA-6b3jR:
13.82
1ykiB-6b3jR:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6b3j GLUCAGON-LIKE
PEPTIDE 1 RECEPTOR
(Homo
sapiens) 		4 / 8 PHE R 321
ASN R 320
GLU R 247
GLY R 248
 None
 0.90A 1ykiC-6b3jR:
undetectable
1ykiD-6b3jR:
undetectable		 1ykiC-6b3jR:
13.82
1ykiD-6b3jR:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6b3j GLUCAGON-LIKE
PEPTIDE 1 RECEPTOR
(Homo
sapiens) 		4 / 8 PHE R 321
ASN R 320
GLU R 247
GLY R 248
 None
 0.90A 1ykiC-6b3jR:
undetectable
1ykiD-6b3jR:
undetectable		 1ykiC-6b3jR:
13.82
1ykiD-6b3jR:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 6b3j GLUCAGON-LIKE
PEPTIDE 1 RECEPTOR
(Homo
sapiens) 		3 / 3 ARG R  43
ARG R  40
TRP R  39
 None
 1.42A 4cpzC-6b3jR:
undetectable		 4cpzC-6b3jR:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 6b3j GLUCAGON-LIKE
PEPTIDE 1 RECEPTOR
(Homo
sapiens) 		3 / 3 ARG R  43
ARG R  40
TRP R  39
 None
 1.48A 4cpzH-6b3jR:
undetectable		 4cpzH-6b3jR:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H3D_A_DHIA601_0
(DUF2338
DOMAIN-CONTAINING
PROTEIN)		 6b3j GLUCAGON-LIKE
PEPTIDE 1 RECEPTOR
(Homo
sapiens) 		4 / 5 TYR R 250
ASN R 177
TYR R 178
PHE R 266
 None
 1.29A 6h3dA-6b3jR:
undetectable		 6h3dA-6b3jR:
undetectable