SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b3o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 6b3o SPIKE GLYCOPROTEIN
(Murine
coronavirus) 		4 / 6 TYR A1111
GLY A 758
PHE A1115
SER A1116
 None
 0.88A 2a3cA-6b3oA:
undetectable		 2a3cA-6b3oA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 6b3o SPIKE GLYCOPROTEIN
(Murine
coronavirus) 		4 / 6 TYR A1111
GLY A 758
PHE A1115
SER A1116
 None
 0.81A 2a3cB-6b3oA:
undetectable		 2a3cB-6b3oA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 6b3o SPIKE GLYCOPROTEIN
(Murine
coronavirus) 		4 / 6 GLY A1157
PHE A1155
PRO A1141
LYS A1142
 None
 1.29A 2m2oB-6b3oA:
undetectable		 2m2oB-6b3oA:
4.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 6b3o SPIKE GLYCOPROTEIN
(Murine
coronavirus) 		4 / 6 GLY A 758
VAL A1118
SER A1116
THR A 756
 None
 1.00A 3tj7A-6b3oA:
undetectable
3tj7B-6b3oA:
undetectable		 3tj7A-6b3oA:
17.31
3tj7B-6b3oA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 6b3o SPIKE GLYCOPROTEIN
(Murine
coronavirus) 		4 / 6 GLY A 758
VAL A1118
SER A1116
THR A 756
 None
 0.97A 3tj7C-6b3oA:
undetectable
3tj7D-6b3oA:
undetectable		 3tj7C-6b3oA:
17.31
3tj7D-6b3oA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 6b3o SPIKE GLYCOPROTEIN
(Murine
coronavirus) 		4 / 6 VAL A1118
SER A1116
THR A 756
GLY A 758
 None
 1.00A 3tj7C-6b3oA:
undetectable
3tj7D-6b3oA:
undetectable		 3tj7C-6b3oA:
17.31
3tj7D-6b3oA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 6b3o SPIKE GLYCOPROTEIN
(Murine
coronavirus) 		4 / 6 THR A 784
ASN A 783
GLY A 781
ASP A 782
 None
 1.39A 3w9tE-6b3oA:
undetectable		 3w9tE-6b3oA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6b3o SPIKE GLYCOPROTEIN
(Murine
coronavirus) 		3 / 3 GLY A1096
THR A1124
PRO A 752
 None
 0.61A 5v5zA-6b3oA:
undetectable		 5v5zA-6b3oA:
21.35