SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 6b3p AMY13K
([Eubacterium]
rectale) 		3 / 3 GLU A 262
ASN A 184
TRP A 277
 None
 1.26A 1r15C-6b3pA:
undetectable		 1r15C-6b3pA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 6b3p AMY13K
([Eubacterium]
rectale) 		4 / 5 SER A 362
SER A 364
THR A 182
ASN A 184
 None
FMT  A 422 (-3.2A)
None
None
 1.12A 1yvpA-6b3pA:
undetectable		 1yvpA-6b3pA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 6b3p AMY13K
([Eubacterium]
rectale) 		4 / 6 SER A 362
SER A 364
THR A 182
ASN A 184
 None
FMT  A 422 (-3.2A)
None
None
 1.09A 1yvpB-6b3pA:
undetectable		 1yvpB-6b3pA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 6b3p AMY13K
([Eubacterium]
rectale) 		4 / 6 PHE A 345
ILE A 356
VAL A 358
PHE A 341
 None
 0.92A 2cizA-6b3pA:
undetectable		 2cizA-6b3pA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 6b3p AMY13K
([Eubacterium]
rectale) 		4 / 7 THR A 306
VAL A 332
THR A 334
VAL A 280
 None
FMT  A 421 (-4.1A)
EDO  A 411 ( 3.8A)
EDO  A 411 (-4.1A)
 0.41A 3em0B-6b3pA:
undetectable		 3em0B-6b3pA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 6b3p AMY13K
([Eubacterium]
rectale) 		4 / 7 TYR A 297
TRP A 299
TRP A 314
ASN A 355
 GLC  A 405 (-3.2A)
GLC  A 406 ( 2.9A)
GLC  A 405 (-2.7A)
GLC  A 406 (-2.8A)
 0.76A 3k8mA-6b3pA:
2.7		 3k8mA-6b3pA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 6b3p AMY13K
([Eubacterium]
rectale) 		4 / 7 TYR A 297
TRP A 299
TRP A 314
ASN A 355
 GLC  A 405 (-3.2A)
GLC  A 406 ( 2.9A)
GLC  A 405 (-2.7A)
GLC  A 406 (-2.8A)
 0.78A 3k8mB-6b3pA:
3.5		 3k8mB-6b3pA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6b3p AMY13K
([Eubacterium]
rectale) 		5 / 11 ILE A 197
ALA A 205
GLY A 206
GLU A 207
GLY A 243
 None
None
None
None
FMT  A 417 (-3.0A)
 1.10A 4e47A-6b3pA:
undetectable		 4e47A-6b3pA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6b3p AMY13K
([Eubacterium]
rectale) 		5 / 11 ILE A 197
ALA A 205
GLY A 206
GLU A 207
GLY A 243
 None
None
None
None
FMT  A 417 (-3.0A)
 1.12A 4e47B-6b3pA:
undetectable		 4e47B-6b3pA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6b3p AMY13K
([Eubacterium]
rectale) 		5 / 11 ILE A 197
ALA A 205
GLY A 206
GLU A 207
GLY A 243
 None
None
None
None
FMT  A 417 (-3.0A)
 1.13A 4jdsA-6b3pA:
undetectable		 4jdsA-6b3pA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6b3p AMY13K
([Eubacterium]
rectale) 		5 / 11 ILE A 197
ALA A 205
GLY A 206
GLU A 207
GLY A 243
 None
None
None
None
FMT  A 417 (-3.0A)
 1.11A 4jdsB-6b3pA:
undetectable		 4jdsB-6b3pA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 6b3p AMY13K
([Eubacterium]
rectale) 		3 / 3 GLU A 366
THR A 224
HIS A 226
 None
FMT  A 422 ( 2.8A)
FMT  A 420 (-3.5A)
 0.82A 4q15A-6b3pA:
undetectable		 4q15A-6b3pA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 6b3p AMY13K
([Eubacterium]
rectale) 		3 / 3 GLU A 366
THR A 224
HIS A 226
 None
FMT  A 422 ( 2.8A)
FMT  A 420 (-3.5A)
 0.83A 4ydqB-6b3pA:
undetectable		 4ydqB-6b3pA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6b3p AMY13K
([Eubacterium]
rectale) 		5 / 11 ILE A 197
ALA A 205
GLY A 206
GLU A 207
GLY A 243
 None
None
None
None
FMT  A 417 (-3.0A)
 1.07A 5ayfA-6b3pA:
undetectable		 5ayfA-6b3pA:
19.70