SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b3r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4F_B_ADNB602_1 (S-ADENOSYLHOMOCYSTEI NE HYDROLASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 12	LEU A1746 LEU A1186 LEU A1185 GLY A1173 PHE A1749	None	1.38A	1d4fB-6b3rA: undetectable	1d4fB-6b3rA: 10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4F_D_ADND604_1 (S-ADENOSYLHOMOCYSTEI NE HYDROLASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 12	LEU A1746 LEU A1186 LEU A1185 GLY A1173 PHE A1749	None	1.42A	1d4fD-6b3rA: undetectable	1d4fD-6b3rA: 10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_B_BEZB504_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 7	ILE A1990 ALA A2079 ILE A2057 LYS A2086	None	1.00A	1oniB-6b3rA: undetectable 1oniC-6b3rA: undetectable	1oniB-6b3rA: undetectable 1oniC-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RQP_B_SAMB500_1 (5'-FLUORO-5'-DEOXYAD ENOSINE SYNTHASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	ASN A2161 SER A2168 ARG A2169 ALA A2160	None	1.16A	1rqpC-6b3rA: undetectable	1rqpC-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RQP_C_SAMC500_0 (5'-FLUORO-5'-DEOXYAD ENOSINE SYNTHASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	ASN A2161 SER A2168 ARG A2169 ALA A2160	None	1.13A	1rqpA-6b3rA: undetectable	1rqpA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TW4_A_CHDA130_0 (FATTY ACID-BINDING PROTEIN)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 12	LEU A1545 ALA A1311 HIS A1655 ILE A1656 LEU A1659	None	1.11A	1tw4A-6b3rA: undetectable	1tw4A-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TW4_B_CHDB1130_0 (FATTY ACID-BINDING PROTEIN)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 12	LEU A2358 LEU A2354 LEU A2405 ILE A2296 ILE A2315	None	1.28A	1tw4B-6b3rA: undetectable	1tw4B-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UKB_A_BEZA1301_0 (2-HYDROXY-6-OXO-7-ME THYLOCTA-2,4-DIENOAT E HYDROLASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 6	LEU A 835 PHE A 838 ALA A 839 LEU A 852	None	0.89A	1ukbA-6b3rA: undetectable	1ukbA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WMQ_A_HISA2001_0 (HUT OPERON POSITIVE REGULATORY PROTEIN)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 6	ARG A1538 ARG A1159 ILE A1144 HIS A1145	None	0.97A	1wmqA-6b3rA: undetectable	1wmqA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WMQ_B_HISB1001_0 (HUT OPERON POSITIVE REGULATORY PROTEIN)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 6	ARG A1538 ARG A1159 ILE A1144 HIS A1145	None	0.97A	1wmqB-6b3rA: undetectable	1wmqB-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WPU_A_HISA2001_0 (HUT OPERON POSITIVE REGULATORY PROTEIN)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 6	ARG A1538 ARG A1159 ILE A1144 HIS A1145	None	0.97A	1wpuA-6b3rA: undetectable	1wpuA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WPU_B_HISB1001_0 (HUT OPERON POSITIVE REGULATORY PROTEIN)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 6	ARG A1538 ARG A1159 ILE A1144 HIS A1145	None	0.97A	1wpuB-6b3rA: undetectable	1wpuB-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRQ_A_HISA2001_0 (HUT OPERON POSITIVE REGULATORY PROTEIN)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 6	ARG A1538 ARG A1159 ILE A1144 HIS A1145	None	0.92A	1wrqA-6b3rA: undetectable	1wrqA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRQ_B_HISB1001_0 (HUT OPERON POSITIVE REGULATORY PROTEIN)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 6	ARG A1538 ARG A1159 ILE A1144 HIS A1145	None	0.93A	1wrqB-6b3rA: undetectable	1wrqB-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XOQ_A_ROFA502_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	3 / 3	ASN A1755 TRP A1754 GLN A1748	None	1.35A	1xoqA-6b3rA: undetectable	1xoqA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z11_B_8MOB501_0 (CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	6 / 11	VAL A1218 PHE A1287 ILE A1002 GLY A1014 ILE A1020 LEU A1021	None	1.40A	1z11B-6b3rA: undetectable	1z11B-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HC4_A_VDXA525_2 (VITAMIN D RECEPTOR)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 7	LEU A2342 LEU A2317 ILE A2432 TRP A2430	None	0.96A	2hc4A-6b3rA: undetectable	2hc4A-6b3rA: 15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JN3_A_JN3A130_1 (FATTY ACID-BINDING PROTEIN, LIVER)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 12	LEU A1545 ALA A1311 HIS A1655 ILE A1656 LEU A1659	None	1.08A	2jn3A-6b3rA: undetectable	2jn3A-6b3rA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OAX_D_SNLD4001_2 (MINERALOCORTICOID RECEPTOR)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	LEU A2117 LEU A2110 CYH A2167 THR A2171	None	1.43A	2oaxD-6b3rA: undetectable	2oaxD-6b3rA: 19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6H_A_CXXA801_1 (TRANSPORTER)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 11	LEU A 822 LEU A1094 VAL A1001 GLN A1004 LEU A 815	None	1.27A	2q6hA-6b3rA: undetectable	2q6hA-6b3rA: 10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q72_A_IXXA802_1 (TRANSPORTER)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 6	ILE A2164 SER A2168 ARG A2169 ILE A2503	None	1.17A	2q72A-6b3rA: 1.7	2q72A-6b3rA: 10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V7U_A_SAMA1299_0 (5'-FLUORO-5'-DEOXY ADENOSINE SYNTHETASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	ASN A2161 SER A2168 ARG A2169 ALA A2160	None	1.09A	2v7uA-6b3rA: undetectable	2v7uA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VQY_A_PARA1201_2 (AAC(6')-IB)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	3 / 3	TRP A1064 GLN A 892 TRP A1079	None	1.29A	2vqyA-6b3rA: undetectable	2vqyA-6b3rA: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_A_DIFA1375_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	3 / 3	LEU A1746 TYR A1745 GLN A1748	None	0.69A	2wekA-6b3rA: undetectable	2wekA-6b3rA: 13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XRL_A_DXTA1211_1 (TETRACYCLINE REPRESSOR PROTEIN CLASS D)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 12	SER A1223 THR A1219 VAL A1218 LEU A1017 ILE A1002	None	1.31A	2xrlA-6b3rA: 1.8	2xrlA-6b3rA: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	ARG A2544 MET A2539 THR A2538 LEU A2532	None	1.30A	3ag1J-6b3rA: undetectable	3ag1J-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	ARG A2544 MET A2539 THR A2538 LEU A2532	None	1.28A	3ag4J-6b3rA: undetectable	3ag4J-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H52_A_486A3_1 (GLUCOCORTICOID RECEPTOR)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 12	MET A1006 ASN A1225 GLY A1014 VAL A1018 MET A1226	None	1.34A	3h52A-6b3rA: undetectable	3h52A-6b3rA: 17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJO_B_EAAB211_1 (GLUTATHIONE S-TRANSFERASE P)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	VAL A1701 ILE A1694 VAL A1788 ASN A1698	None	0.89A	3hjoB-6b3rA: undetectable	3hjoB-6b3rA: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J7Z_A_ERYA9000_0 (23S RRNA 50S RIBOSOMAL PROTEIN L22 ERMCL NASCENT CHAIN)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	3 / 3	LYS A1355 ILE A2162 PHE A2163	None	0.67A	3j7zS-6b3rA: undetectable 3j7za-6b3rA: undetectable	3j7zS-6b3rA: undetectable 3j7za-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QXV_E_MTXE2000_1 (ANTI-METHOTREXATE CDR1-4 GRAFT VHH)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 12	ALA A1174 ARG A1176 SER A1250 VAL A1742 TYR A1184	None	1.30A	3qxvE-6b3rA: undetectable	3qxvE-6b3rA: 21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R24_A_SAMA302_0 (2'-O-METHYL TRANSFERASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 12	GLY A1173 SER A1178 GLY A1279 CYH A1188 PHE A1170	None	1.22A	3r24A-6b3rA: undetectable	3r24A-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_J_ACHJ323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	GLU A1688 PHE A1320 TYR A1323 ASN A1327	None	1.14A	3rqwF-6b3rA: 2.5 3rqwJ-6b3rA: undetectable	3rqwF-6b3rA: undetectable 3rqwJ-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SNF_A_ACTA110_0 (PROTEIN P-30)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	ILE A 930 THR A 857 THR A 854 SER A 853	None	1.19A	3snfA-6b3rA: undetectable	3snfA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_C_SUEC1201_2 (NS3 PROTEASE, NS4A PROTEIN)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	TYR A1048 ILE A1077 LEU A1080 LYS A1078	None	1.10A	3sueC-6b3rA: undetectable	3sueC-6b3rA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D33_A_MTLA870_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	SER A2168 ARG A2169 GLU A2495 ILE A2165	None	1.14A	4d33A-6b3rA: undetectable	4d33A-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D33_B_MTLB870_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 7	SER A2168 ARG A2169 GLU A2495 ILE A2165	None	1.14A	4d33B-6b3rA: undetectable	4d33B-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8H_A_RKEA401_1 (PROTON-GATED ION CHANNEL)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	ASP A1984 ASP A1987 PHE A2090 LEU A2053	None	0.76A	4f8hA-6b3rA: 3.0 4f8hB-6b3rA: 3.0	4f8hA-6b3rA: 16.81 4f8hB-6b3rA: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8H_B_RKEB401_1 (PROTON-GATED ION CHANNEL)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	ASP A1984 ASP A1987 PHE A2090 LEU A2053	None	0.78A	4f8hB-6b3rA: 3.0 4f8hC-6b3rA: 3.0	4f8hB-6b3rA: 16.81 4f8hC-6b3rA: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8H_C_RKEC401_1 (PROTON-GATED ION CHANNEL)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	ASP A1984 ASP A1987 PHE A2090 LEU A2053	None	0.78A	4f8hC-6b3rA: undetectable 4f8hD-6b3rA: undetectable	4f8hC-6b3rA: 16.81 4f8hD-6b3rA: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8H_D_RKED401_1 (PROTON-GATED ION CHANNEL)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	ASP A1984 ASP A1987 PHE A2090 LEU A2053	None	0.77A	4f8hD-6b3rA: 3.0 4f8hE-6b3rA: 3.0	4f8hD-6b3rA: 16.81 4f8hE-6b3rA: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8H_E_RKEE401_1 (PROTON-GATED ION CHANNEL)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	PHE A2090 LEU A2053 ASP A1984 ASP A1987	None	0.76A	4f8hA-6b3rA: 3.0 4f8hE-6b3rA: 3.0	4f8hA-6b3rA: 16.81 4f8hE-6b3rA: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGZ_B_CQAB301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	GLY A2107 VAL A2155 GLU A2156 TYR A2159	None	0.55A	4fgzB-6b3rA: undetectable	4fgzB-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HXY_B_ACAB502_1 (PLM1)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 7	GLN A1356 TYR A1359 LEU A2506 ASP A2509	None	1.21A	4hxyB-6b3rA: undetectable	4hxyB-6b3rA: 11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JTP_A_ASCA802_0 (RRNA N-GLYCOSIDASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	ILE A1029 ASN A1035 TYR A1036 ILE A1020	None	1.03A	4jtpA-6b3rA: undetectable	4jtpA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K39_A_SAMA504_0 (ANAEROBIC SULFATASE-MATURATING ENZYME)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 12	TYR A2398 PHE A2372 ASN A2385 LEU A2390 LEU A2399	None	1.39A	4k39A-6b3rA: undetectable	4k39A-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLT_A_GCSA302_1 (CHITOSANASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	ARG A2514 THR A2145 THR A2143 ASP A2144	None	1.46A	4oltA-6b3rA: undetectable	4oltA-6b3rA: 17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLT_B_GCSB302_1 (CHITOSANASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	ARG A2514 THR A2145 THR A2143 ASP A2144	None	1.45A	4oltB-6b3rA: 3.8	4oltB-6b3rA: 17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QKN_A_JMSA602_1 (ALPHA-KETOGLUTARATE- DEPENDENT DIOXYGENASE FTO)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	LEU A1541 THR A1312 LEU A1534 SER A1317	None	0.94A	4qknA-6b3rA: 3.2	4qknA-6b3rA: 11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_A_GCSA302_1 (CHITOSANASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	ARG A2514 THR A2145 THR A2143 ASP A2144	None	1.47A	4qwpA-6b3rA: undetectable	4qwpA-6b3rA: 17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_B_GCSB306_1 (CHITOSANASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	ARG A2514 THR A2145 THR A2143 ASP A2144	None	1.45A	4qwpB-6b3rA: 0.4	4qwpB-6b3rA: 17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZT_B_ACTB201_0 (RETINOL-BINDING PROTEIN 2)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	TYR A1803 GLU A1537 LEU A1322 GLN A1315	None	1.48A	4qztB-6b3rA: undetectable	4qztB-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCK_B_SAMB2409_0 (RNA-DIRECTED RNA POLYMERASE L)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	5 / 12	GLY A1549 LEU A1309 ASP A1308 THR A1196 ALA A1313	None	1.13A	4uckB-6b3rA: undetectable	4uckB-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5O_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 7	GLN A2222 PRO A2223 ILE A2224 ASP A2326	None	1.02A	4w5oA-6b3rA: undetectable	4w5oA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4E_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 7	GLN A2222 PRO A2223 ILE A2224 ASP A2326	None	1.02A	4z4eA-6b3rA: undetectable	4z4eA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4G_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 7	GLN A2222 PRO A2223 ILE A2224 ASP A2326	None	1.00A	4z4gA-6b3rA: undetectable	4z4gA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4H_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	GLN A2222 PRO A2223 ILE A2224 ASP A2326	None	1.00A	4z4hA-6b3rA: undetectable	4z4hA-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CVT_B_ACTB200_0 (N5-CARBOXYAMINOIMIDA ZOLE RIBONUCLEOTIDE MUTASE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	3 / 3	ASN A2161 ALA A2160 ARG A2126	None	0.65A	5cvtB-6b3rA: undetectable	5cvtB-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_A_7V7A201_1 (ENDO-1,4-BETA-XYLANA SE A)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	TRP A1730 THR A1732 THR A1737 GLN A1789	None	0.91A	5tzoA-6b3rA: undetectable	5tzoA-6b3rA: 14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_B_7V7B202_1 (ENDO-1,4-BETA-XYLANA SE A)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	TRP A1730 THR A1732 THR A1737 GLN A1789	None	0.94A	5tzoB-6b3rA: undetectable	5tzoB-6b3rA: 14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_C_7V7C202_1 (ENDO-1,4-BETA-XYLANA SE A)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 8	TRP A1730 THR A1732 THR A1737 GLN A1789	None	0.91A	5tzoC-6b3rA: undetectable	5tzoC-6b3rA: 14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCG_A_08YA602_2 (CYTOCHROME P450 3A4)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	3 / 3	ARG A 942 ARG A 948 ARG A 802	None	0.96A	5vcgA-6b3rA: undetectable	5vcgA-6b3rA: 10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	ARG A2544 MET A2539 THR A2538 LEU A2532	None	1.26A	5x19J-6b3rA: undetectable	5x19J-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	ARG A2544 MET A2539 THR A2538 LEU A2532	None	1.27A	5x1bJ-6b3rA: undetectable	5x1bJ-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 5	LEU A2371 PHE A2372 PHE A2319 LEU A2230	None	1.00A	5x1bP-6b3rA: 3.3	5x1bP-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FOS_B_PQNB2002_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 6	ARG A2295 TRP A2294 LEU A2293 ALA A2292	None	0.99A	6fosB-6b3rA: undetectable	6fosB-6b3rA: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G1P_B_ACTB403_0 (ADP-RIBOSYLHYDROLASE LIKE 2)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	3 / 3	PHE A2272 ARG A2377 GLN A2275	None	1.09A	6g1pB-6b3rA: undetectable	6g1pB-6b3rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GQI_A_ACTA604_0 (CYCLOHEXANONE MONOOXYGENASE FROM THERMOCRISPUM MUNICIPALE)	6b3r	PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 (Mus musculus)	4 / 6	PRO A2346 ILE A2315 GLY A2311 GLU A2307	None	1.08A	6gqiA-6b3rA: undetectable	6gqiA-6b3rA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1D4F_B_ADNB602_1","S-ADENOSYLHOMOCYSTEINE HYDROLASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"LEU A1746;LEU A1186;LEU A1185;GLY A1173;PHE A1749","None","1.38A","1d4fB-6b3rA:undetectable","1d4fB-6b3rA:10.45"],["1D4F_D_ADND604_1","S-ADENOSYLHOMOCYSTEINE HYDROLASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"LEU A1746;LEU A1186;LEU A1185;GLY A1173;PHE A1749","None","1.42A","1d4fD-6b3rA:undetectable","1d4fD-6b3rA:10.45"],["1ONI_B_BEZB504_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ILE A1990;ALA A2079;ILE A2057;LYS A2086","None","1.00A","1oniB-6b3rA:undetectable;1oniC-6b3rA:undetectable","1oniB-6b3rA:undetectable;1oniC-6b3rA:undetectable"],["1RQP_B_SAMB500_1","5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ASN A2161;SER A2168;ARG A2169;ALA A2160","None","1.16A","1rqpC-6b3rA:undetectable","1rqpC-6b3rA:undetectable"],["1RQP_C_SAMC500_0","5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ASN A2161;SER A2168;ARG A2169;ALA A2160","None","1.13A","1rqpA-6b3rA:undetectable","1rqpA-6b3rA:undetectable"],["1TW4_A_CHDA130_0","FATTY ACID-BINDING PROTEIN","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"LEU A1545;ALA A1311;HIS A1655;ILE A1656;LEU A1659","None","1.11A","1tw4A-6b3rA:undetectable","1tw4A-6b3rA:undetectable"],["1TW4_B_CHDB1130_0","FATTY ACID-BINDING PROTEIN","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"LEU A2358;LEU A2354;LEU A2405;ILE A2296;ILE A2315","None","1.28A","1tw4B-6b3rA:undetectable","1tw4B-6b3rA:undetectable"],["1UKB_A_BEZA1301_0","2-HYDROXY-6-OXO-7-METHYLOCTA-2,4-DIENOATE HYDROLASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"LEU A 835;PHE A 838;ALA A 839;LEU A 852","None","0.89A","1ukbA-6b3rA:undetectable","1ukbA-6b3rA:undetectable"],["1WMQ_A_HISA2001_0","HUT OPERON POSITIVE REGULATORY PROTEIN","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A1538;ARG A1159;ILE A1144;HIS A1145","None","0.97A","1wmqA-6b3rA:undetectable","1wmqA-6b3rA:undetectable"],["1WMQ_B_HISB1001_0","HUT OPERON POSITIVE REGULATORY PROTEIN","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A1538;ARG A1159;ILE A1144;HIS A1145","None","0.97A","1wmqB-6b3rA:undetectable","1wmqB-6b3rA:undetectable"],["1WPU_A_HISA2001_0","HUT OPERON POSITIVE REGULATORY PROTEIN","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A1538;ARG A1159;ILE A1144;HIS A1145","None","0.97A","1wpuA-6b3rA:undetectable","1wpuA-6b3rA:undetectable"],["1WPU_B_HISB1001_0","HUT OPERON POSITIVE REGULATORY PROTEIN","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A1538;ARG A1159;ILE A1144;HIS A1145","None","0.97A","1wpuB-6b3rA:undetectable","1wpuB-6b3rA:undetectable"],["1WRQ_A_HISA2001_0","HUT OPERON POSITIVE REGULATORY PROTEIN","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A1538;ARG A1159;ILE A1144;HIS A1145","None","0.92A","1wrqA-6b3rA:undetectable","1wrqA-6b3rA:undetectable"],["1WRQ_B_HISB1001_0","HUT OPERON POSITIVE REGULATORY PROTEIN","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A1538;ARG A1159;ILE A1144;HIS A1145","None","0.93A","1wrqB-6b3rA:undetectable","1wrqB-6b3rA:undetectable"],["1XOQ_A_ROFA502_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",3,"ASN A1755;TRP A1754;GLN A1748","None","1.35A","1xoqA-6b3rA:undetectable","1xoqA-6b3rA:undetectable"],["1Z11_B_8MOB501_0","CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",6,"VAL A1218;PHE A1287;ILE A1002;GLY A1014;ILE A1020;LEU A1021","None","1.40A","1z11B-6b3rA:undetectable","1z11B-6b3rA:undetectable"],["2HC4_A_VDXA525_2","VITAMIN D RECEPTOR","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"LEU A2342;LEU A2317;ILE A2432;TRP A2430","None","0.96A","2hc4A-6b3rA:undetectable","2hc4A-6b3rA:15.49"],["2JN3_A_JN3A130_1","FATTY ACID-BINDING PROTEIN, LIVER","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"LEU A1545;ALA A1311;HIS A1655;ILE A1656;LEU A1659","None","1.08A","2jn3A-6b3rA:undetectable","2jn3A-6b3rA:16.67"],["2OAX_D_SNLD4001_2","MINERALOCORTICOID RECEPTOR","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"LEU A2117;LEU A2110;CYH A2167;THR A2171","None","1.43A","2oaxD-6b3rA:undetectable","2oaxD-6b3rA:19.11"],["2Q6H_A_CXXA801_1","TRANSPORTER","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"LEU A 822;LEU A1094;VAL A1001;GLN A1004;LEU A 815","None","1.27A","2q6hA-6b3rA:undetectable","2q6hA-6b3rA:10.77"],["2Q72_A_IXXA802_1","TRANSPORTER","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ILE A2164;SER A2168;ARG A2169;ILE A2503","None","1.17A","2q72A-6b3rA:1.7","2q72A-6b3rA:10.77"],["2V7U_A_SAMA1299_0","5'-FLUORO-5'-DEOXY ADENOSINE SYNTHETASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ASN A2161;SER A2168;ARG A2169;ALA A2160","None","1.09A","2v7uA-6b3rA:undetectable","2v7uA-6b3rA:undetectable"],["2VQY_A_PARA1201_2","AAC(6')-IB","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",3,"TRP A1064;GLN A 892;TRP A1079","None","1.29A","2vqyA-6b3rA:undetectable","2vqyA-6b3rA:19.53"],["2WEK_A_DIFA1375_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",3,"LEU A1746;TYR A1745;GLN A1748","None","0.69A","2wekA-6b3rA:undetectable","2wekA-6b3rA:13.43"],["2XRL_A_DXTA1211_1","TETRACYCLINE REPRESSOR PROTEIN CLASS D","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"SER A1223;THR A1219;VAL A1218;LEU A1017;ILE A1002","None","1.31A","2xrlA-6b3rA:1.8","2xrlA-6b3rA:21.74"],["3AG1_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A2544;MET A2539;THR A2538;LEU A2532","None","1.30A","3ag1J-6b3rA:undetectable","3ag1J-6b3rA:undetectable"],["3AG4_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A2544;MET A2539;THR A2538;LEU A2532","None","1.28A","3ag4J-6b3rA:undetectable","3ag4J-6b3rA:undetectable"],["3H52_A_486A3_1","GLUCOCORTICOID RECEPTOR","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"MET A1006;ASN A1225;GLY A1014;VAL A1018;MET A1226","None","1.34A","3h52A-6b3rA:undetectable","3h52A-6b3rA:17.80"],["3HJO_B_EAAB211_1","GLUTATHIONE S-TRANSFERASE P","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"VAL A1701;ILE A1694;VAL A1788;ASN A1698","None","0.89A","3hjoB-6b3rA:undetectable","3hjoB-6b3rA:20.43"],["3J7Z_A_ERYA9000_0","23S RRNA;50S RIBOSOMAL PROTEIN L22;ERMCL NASCENT CHAIN","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",3,"LYS A1355;ILE A2162;PHE A2163","None","0.67A","3j7zS-6b3rA:undetectable;3j7za-6b3rA:undetectable","3j7zS-6b3rA:undetectable;3j7za-6b3rA:undetectable"],["3QXV_E_MTXE2000_1","ANTI-METHOTREXATE CDR1-4 GRAFT VHH","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"ALA A1174;ARG A1176;SER A1250;VAL A1742;TYR A1184","None","1.30A","3qxvE-6b3rA:undetectable","3qxvE-6b3rA:21.54"],["3R24_A_SAMA302_0","2'-O-METHYL TRANSFERASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"GLY A1173;SER A1178;GLY A1279;CYH A1188;PHE A1170","None","1.22A","3r24A-6b3rA:undetectable","3r24A-6b3rA:undetectable"],["3RQW_J_ACHJ323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"GLU A1688;PHE A1320;TYR A1323;ASN A1327","None","1.14A","3rqwF-6b3rA:2.5;3rqwJ-6b3rA:undetectable","3rqwF-6b3rA:undetectable;3rqwJ-6b3rA:undetectable"],["3SNF_A_ACTA110_0","PROTEIN P-30","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ILE A 930;THR A 857;THR A 854;SER A 853","None","1.19A","3snfA-6b3rA:undetectable","3snfA-6b3rA:undetectable"],["3SUE_C_SUEC1201_2","NS3 PROTEASE, NS4A PROTEIN","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"TYR A1048;ILE A1077;LEU A1080;LYS A1078","None","1.10A","3sueC-6b3rA:undetectable","3sueC-6b3rA:18.52"],["4D33_A_MTLA870_0","NITRIC OXIDE SYNTHASE, ENDOTHELIAL","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"SER A2168;ARG A2169;GLU A2495;ILE A2165","None","1.14A","4d33A-6b3rA:undetectable","4d33A-6b3rA:undetectable"],["4D33_B_MTLB870_0","NITRIC OXIDE SYNTHASE, ENDOTHELIAL","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"SER A2168;ARG A2169;GLU A2495;ILE A2165","None","1.14A","4d33B-6b3rA:undetectable","4d33B-6b3rA:undetectable"],["4F8H_A_RKEA401_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ASP A1984;ASP A1987;PHE A2090;LEU A2053","None","0.76A","4f8hA-6b3rA:3.0;4f8hB-6b3rA:3.0","4f8hA-6b3rA:16.81;4f8hB-6b3rA:16.81"],["4F8H_B_RKEB401_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ASP A1984;ASP A1987;PHE A2090;LEU A2053","None","0.78A","4f8hB-6b3rA:3.0;4f8hC-6b3rA:3.0","4f8hB-6b3rA:16.81;4f8hC-6b3rA:16.81"],["4F8H_C_RKEC401_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ASP A1984;ASP A1987;PHE A2090;LEU A2053","None","0.78A","4f8hC-6b3rA:undetectable;4f8hD-6b3rA:undetectable","4f8hC-6b3rA:16.81;4f8hD-6b3rA:16.81"],["4F8H_D_RKED401_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ASP A1984;ASP A1987;PHE A2090;LEU A2053","None","0.77A","4f8hD-6b3rA:3.0;4f8hE-6b3rA:3.0","4f8hD-6b3rA:16.81;4f8hE-6b3rA:16.81"],["4F8H_E_RKEE401_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"PHE A2090;LEU A2053;ASP A1984;ASP A1987","None","0.76A","4f8hA-6b3rA:3.0;4f8hE-6b3rA:3.0","4f8hA-6b3rA:16.81;4f8hE-6b3rA:16.81"],["4FGZ_B_CQAB301_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"GLY A2107;VAL A2155;GLU A2156;TYR A2159","None","0.55A","4fgzB-6b3rA:undetectable","4fgzB-6b3rA:undetectable"],["4HXY_B_ACAB502_1","PLM1","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"GLN A1356;TYR A1359;LEU A2506;ASP A2509","None","1.21A","4hxyB-6b3rA:undetectable","4hxyB-6b3rA:11.09"],["4JTP_A_ASCA802_0","RRNA N-GLYCOSIDASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ILE A1029;ASN A1035;TYR A1036;ILE A1020","None","1.03A","4jtpA-6b3rA:undetectable","4jtpA-6b3rA:undetectable"],["4K39_A_SAMA504_0","ANAEROBIC SULFATASE-MATURATING ENZYME","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"TYR A2398;PHE A2372;ASN A2385;LEU A2390;LEU A2399","None","1.39A","4k39A-6b3rA:undetectable","4k39A-6b3rA:undetectable"],["4OLT_A_GCSA302_1","CHITOSANASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A2514;THR A2145;THR A2143;ASP A2144","None","1.46A","4oltA-6b3rA:undetectable","4oltA-6b3rA:17.07"],["4OLT_B_GCSB302_1","CHITOSANASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A2514;THR A2145;THR A2143;ASP A2144","None","1.45A","4oltB-6b3rA:3.8","4oltB-6b3rA:17.07"],["4QKN_A_JMSA602_1","ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"LEU A1541;THR A1312;LEU A1534;SER A1317","None","0.94A","4qknA-6b3rA:3.2","4qknA-6b3rA:11.29"],["4QWP_A_GCSA302_1","CHITOSANASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A2514;THR A2145;THR A2143;ASP A2144","None","1.47A","4qwpA-6b3rA:undetectable","4qwpA-6b3rA:17.07"],["4QWP_B_GCSB306_1","CHITOSANASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A2514;THR A2145;THR A2143;ASP A2144","None","1.45A","4qwpB-6b3rA:0.4","4qwpB-6b3rA:17.07"],["4QZT_B_ACTB201_0","RETINOL-BINDING PROTEIN 2","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"TYR A1803;GLU A1537;LEU A1322;GLN A1315","None","1.48A","4qztB-6b3rA:undetectable","4qztB-6b3rA:undetectable"],["4UCK_B_SAMB2409_0","RNA-DIRECTED RNA POLYMERASE L","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",5,"GLY A1549;LEU A1309;ASP A1308;THR A1196;ALA A1313","None","1.13A","4uckB-6b3rA:undetectable","4uckB-6b3rA:undetectable"],["4W5O_A_IPHA904_0","PROTEIN ARGONAUTE-2","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"GLN A2222;PRO A2223;ILE A2224;ASP A2326","None","1.02A","4w5oA-6b3rA:undetectable","4w5oA-6b3rA:undetectable"],["4Z4E_A_IPHA904_0","PROTEIN ARGONAUTE-2","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"GLN A2222;PRO A2223;ILE A2224;ASP A2326","None","1.02A","4z4eA-6b3rA:undetectable","4z4eA-6b3rA:undetectable"],["4Z4G_A_IPHA902_0","PROTEIN ARGONAUTE-2","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"GLN A2222;PRO A2223;ILE A2224;ASP A2326","None","1.00A","4z4gA-6b3rA:undetectable","4z4gA-6b3rA:undetectable"],["4Z4H_A_IPHA904_0","PROTEIN ARGONAUTE-2","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"GLN A2222;PRO A2223;ILE A2224;ASP A2326","None","1.00A","4z4hA-6b3rA:undetectable","4z4hA-6b3rA:undetectable"],["5CVT_B_ACTB200_0","N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE MUTASE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",3,"ASN A2161;ALA A2160;ARG A2126","None","0.65A","5cvtB-6b3rA:undetectable","5cvtB-6b3rA:undetectable"],["5TZO_A_7V7A201_1","ENDO-1,4-BETA-XYLANASE A","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"TRP A1730;THR A1732;THR A1737;GLN A1789","None","0.91A","5tzoA-6b3rA:undetectable","5tzoA-6b3rA:14.14"],["5TZO_B_7V7B202_1","ENDO-1,4-BETA-XYLANASE A","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"TRP A1730;THR A1732;THR A1737;GLN A1789","None","0.94A","5tzoB-6b3rA:undetectable","5tzoB-6b3rA:14.14"],["5TZO_C_7V7C202_1","ENDO-1,4-BETA-XYLANASE A","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"TRP A1730;THR A1732;THR A1737;GLN A1789","None","0.91A","5tzoC-6b3rA:undetectable","5tzoC-6b3rA:14.14"],["5VCG_A_08YA602_2","CYTOCHROME P450 3A4","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",3,"ARG A 942;ARG A 948;ARG A 802","None","0.96A","5vcgA-6b3rA:undetectable","5vcgA-6b3rA:10.88"],["5X19_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A2544;MET A2539;THR A2538;LEU A2532","None","1.26A","5x19J-6b3rA:undetectable","5x19J-6b3rA:undetectable"],["5X1B_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A2544;MET A2539;THR A2538;LEU A2532","None","1.27A","5x1bJ-6b3rA:undetectable","5x1bJ-6b3rA:undetectable"],["5X1B_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"LEU A2371;PHE A2372;PHE A2319;LEU A2230","None","1.00A","5x1bP-6b3rA:3.3","5x1bP-6b3rA:undetectable"],["6FOS_B_PQNB2002_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"ARG A2295;TRP A2294;LEU A2293;ALA A2292","None","0.99A","6fosB-6b3rA:undetectable","6fosB-6b3rA:17.39"],["6G1P_B_ACTB403_0","ADP-RIBOSYLHYDROLASE LIKE 2","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",3,"PHE A2272;ARG A2377;GLN A2275","None","1.09A","6g1pB-6b3rA:undetectable","6g1pB-6b3rA:undetectable"],["6GQI_A_ACTA604_0","CYCLOHEXANONE MONOOXYGENASE FROM THERMOCRISPUM MUNICIPALE","6b3r","PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1","Mus musculus",4,"PRO A2346;ILE A2315;GLY A2311;GLU A2307","None","1.08A","6gqiA-6b3rA:undetectable","6gqiA-6b3rA:undetectable"]]