SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		4 / 7 TYR A 775
PHE A 774
PHE A 771
PHE A 723
 None
 0.95A 1e71M-6b3yA:
undetectable		 1e71M-6b3yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		4 / 7 TYR A 775
PHE A 774
PHE A 771
PHE A 723
 None
 0.96A 1e72M-6b3yA:
undetectable		 1e72M-6b3yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		5 / 9 LEU A 827
LEU A 807
VAL A 811
GLY A 818
ALA A 877
 None
 1.18A 1e7aA-6b3yA:
undetectable		 1e7aA-6b3yA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		5 / 11 LEU A 879
LEU A 864
ILE A 820
PHE A 875
LEU A 829
 None
 1.22A 2q6hA-6b3yA:
undetectable		 2q6hA-6b3yA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		5 / 11 LEU A 879
LEU A 864
ILE A 820
PHE A 875
LEU A 829
 None
 1.22A 2qeiA-6b3yA:
undetectable		 2qeiA-6b3yA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		3 / 3 MET A 730
GLU A 741
ASN A 722
 None
 1.13A 3a27A-6b3yA:
undetectable		 3a27A-6b3yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		3 / 3 MET A 795
VAL A 788
GLU A 802
 None
 0.91A 3c6gA-6b3yA:
undetectable		 3c6gA-6b3yA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		5 / 11 PHE A 774
PHE A 771
PHE A 735
ILE A 744
THR A 914
 None
 1.15A 3t3rA-6b3yA:
undetectable		 3t3rA-6b3yA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		5 / 10 PHE A 774
PHE A 771
PHE A 735
ILE A 744
THR A 914
 None
 1.21A 3t3rD-6b3yA:
undetectable		 3t3rD-6b3yA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		5 / 12 LEU A 917
LEU A 885
MET A 889
VAL A 890
MET A 893
 None
 1.26A 4ojbA-6b3yA:
undetectable		 4ojbA-6b3yA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		5 / 12 LEU A 917
LEU A 885
MET A 889
VAL A 890
MET A 893
 None
 1.30A 4okbA-6b3yA:
undetectable		 4okbA-6b3yA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		5 / 11 LEU A 918
VAL A 916
ASN A 915
PHE A 941
GLY A 896
 None
 1.24A 4zbqA-6b3yA:
undetectable		 4zbqA-6b3yA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		5 / 9 LEU A 790
LEU A 830
ARG A 826
MET A 822
ALA A 821
 None
 1.29A 5g44A-6b3yA:
undetectable		 5g44A-6b3yA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		4 / 6 ASP A 756
HIS A 752
ILE A 750
TYR A 940
 None
 1.04A 5ih0A-6b3yA:
undetectable		 5ih0A-6b3yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3
(Mus
musculus) 		4 / 6 LEU A 794
LYS A 825
GLU A 802
LEU A 798
 None
 1.42A 5xooA-6b3yA:
undetectable		 5xooA-6b3yA:
21.84