SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b4p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 9 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
PHE A 111
 None
 0.64A 1bkfA-6b4pA:
19.3		 1bkfA-6b4pA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 9 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TYR A  94
PHE A 111
 None
 0.55A 1bkfA-6b4pA:
19.3		 1bkfA-6b4pA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 12 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A  68
TYR A  94
ILE A 103
PHE A 111
 None
 0.72A 1c9hA-6b4pA:
19.2		 1c9hA-6b4pA:
37.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 12 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.72A 1fapA-6b4pA:
19.7		 1fapA-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		6 / 12 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A 103
 None
 1.03A 1fapA-6b4pA:
19.7		 1fapA-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		6 / 12 TYR A  38
PHE A  58
TRP A  71
ILE A  99
ILE A 103
PHE A 111
 None
 1.40A 1fapA-6b4pA:
19.7		 1fapA-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 12 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A  68
TRP A  71
TYR A  94
PHE A 111
 None
 0.69A 1fkbA-6b4pA:
19.6		 1fkbA-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		6 / 12 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A 103
 None
 1.02A 1fkbA-6b4pA:
19.6		 1fkbA-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 12 TYR A  38
PHE A  58
TRP A  71
ILE A  99
PHE A 111
 None
 1.07A 1fkbA-6b4pA:
19.6		 1fkbA-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.68A 1fkfA-6b4pA:
19.3		 1fkfA-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
ILE A 103
PHE A 111
 None
 0.68A 1fkjA-6b4pA:
19.3		 1fkjA-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TYR A  94
ILE A 103
PHE A 111
 None
 0.61A 1fkjA-6b4pA:
19.3		 1fkjA-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 12 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.74A 1fklA-6b4pA:
19.5		 1fklA-6b4pA:
42.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		6 / 12 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A 103
 None
 1.04A 1fklA-6b4pA:
19.5		 1fklA-6b4pA:
42.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		6 / 12 TYR A  38
PHE A  58
TRP A  71
ILE A  99
ILE A 103
PHE A 111
 None
 1.41A 1fklA-6b4pA:
19.5		 1fklA-6b4pA:
42.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		4 / 8 SER A  77
ILE A  19
VAL A  36
SER A  50
 None
 1.14A 1kb9A-6b4pA:
undetectable
1kb9C-6b4pA:
undetectable
1kb9D-6b4pA:
undetectable
1kb9E-6b4pA:
undetectable		 1kb9A-6b4pA:
15.02
1kb9C-6b4pA:
15.80
1kb9D-6b4pA:
19.82
1kb9E-6b4pA:
21.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 12 TYR A  38
ASP A  49
GLY A  65
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.36A 1pbkA-6b4pA:
18.1		 1pbkA-6b4pA:
38.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 12 TYR A  38
ASP A  49
GLY A  65
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.59A 1pbkA-6b4pA:
18.1		 1pbkA-6b4pA:
38.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 9 TYR A  38
ASP A  49
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.68A 1q6iA-6b4pA:
16.8		 1q6iA-6b4pA:
27.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 10 TYR A  38
ASP A  49
ARG A  54
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.72A 1q6iB-6b4pA:
16.5		 1q6iB-6b4pA:
27.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
PHE A 111
 None
 0.66A 1tcoC-6b4pA:
19.5		 1tcoC-6b4pA:
44.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TYR A  94
ILE A 103
PHE A 111
 None
 0.60A 1tcoC-6b4pA:
19.5		 1tcoC-6b4pA:
44.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 11 TYR A  38
ASP A  49
ARG A  54
ILE A  68
TYR A  94
LEU A 102
ILE A  99
 None
 1.50A 1yatA-6b4pA:
21.2		 1yatA-6b4pA:
48.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 11 TYR A  38
ASP A  49
ARG A  54
ILE A  68
TYR A  94
LEU A 102
ILE A 103
PHE A 111
 None
 0.56A 1yatA-6b4pA:
21.2		 1yatA-6b4pA:
48.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.45A 1yatA-6b4pA:
21.2		 1yatA-6b4pA:
48.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.62A 1yatA-6b4pA:
21.2		 1yatA-6b4pA:
48.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 11 TYR A  38
ASP A  49
PHE A  58
GLU A  66
ILE A 103
 None
 1.11A 2dg3A-6b4pA:
19.4		 2dg3A-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A  68
TRP A  71
TYR A  94
PHE A 111
 None
 0.68A 2dg3A-6b4pA:
19.4		 2dg3A-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 11 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A  68
TYR A  94
PHE A 111
 None
 0.66A 2dg4A-6b4pA:
19.0		 2dg4A-6b4pA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		6 / 11 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A 103
 None
 1.05A 2dg4A-6b4pA:
19.0		 2dg4A-6b4pA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		6 / 11 TYR A  38
PHE A  58
VAL A  67
ILE A  68
ILE A  99
PHE A 111
 None
 1.20A 2dg4A-6b4pA:
19.0		 2dg4A-6b4pA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 11 ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A  68
TYR A  94
PHE A 111
 None
 0.78A 2dg9A-6b4pA:
19.2		 2dg9A-6b4pA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 11 ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A 103
 None
 1.19A 2dg9A-6b4pA:
19.2		 2dg9A-6b4pA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 11 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TYR A  94
PHE A 111
 None
 0.54A 2dg9A-6b4pA:
19.2		 2dg9A-6b4pA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 11 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A 103
 None
 1.08A 2dg9A-6b4pA:
19.2		 2dg9A-6b4pA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.69A 2fkeA-6b4pA:
19.4		 2fkeA-6b4pA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		6 / 11 TYR A  38
PHE A  48
ASP A  49
VAL A  67
ILE A  68
TRP A  71
 None
 0.87A 2vcdA-6b4pA:
14.7		 2vcdA-6b4pA:
32.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 11 TYR A  38
VAL A  67
ILE A  68
TRP A  71
TYR A  94
 None
 0.82A 2vcdA-6b4pA:
14.7		 2vcdA-6b4pA:
32.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
TRP A  71
TYR A  94
ILE A  99
 None
 1.45A 2vn1A-6b4pA:
21.3		 2vn1A-6b4pA:
43.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 11 TYR A  38
PHE A  48
ASP A  49
ARG A  54
PHE A  58
VAL A  67
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.59A 2vn1A-6b4pA:
21.3		 2vn1A-6b4pA:
43.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 10 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
PHE A 111
 None
 0.59A 2vn1B-6b4pA:
21.5		 2vn1B-6b4pA:
43.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 10 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.59A 3ihzA-6b4pA:
21.4		 3ihzA-6b4pA:
42.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		4 / 8 TYR A  38
ASP A  49
PHE A  58
GLY A 101
 None
 0.64A 3ihzB-6b4pA:
22.0		 3ihzB-6b4pA:
42.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 8 TYR A  38
ASP A  49
PHE A  58
TRP A  71
ILE A 103
 None
 0.75A 3ihzB-6b4pA:
22.0		 3ihzB-6b4pA:
42.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 8 TYR A  38
PHE A  58
TRP A  71
TYR A  94
ILE A 103
 None
 0.61A 3ihzB-6b4pA:
22.0		 3ihzB-6b4pA:
42.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 10 TYR A  38
ASP A  49
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.49A 3kz7A-6b4pA:
18.6		 3kz7A-6b4pA:
35.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 10 TYR A  38
ASP A  49
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.58A 3kz7A-6b4pA:
18.6		 3kz7A-6b4pA:
35.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.34A 3o5rA-6b4pA:
21.2		 3o5rA-6b4pA:
48.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.48A 3o5rA-6b4pA:
21.2		 3o5rA-6b4pA:
48.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 10 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.50A 3uf8A-6b4pA:
20.2		 3uf8A-6b4pA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 10 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.61A 3uf8A-6b4pA:
20.2		 3uf8A-6b4pA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 10 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.66A 3uqaA-6b4pA:
19.9		 3uqaA-6b4pA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 8 TYR A  38
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
PHE A 111
 None
 0.56A 3uqbA-6b4pA:
19.8		 3uqbA-6b4pA:
32.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 8 TYR A  38
PHE A  58
VAL A  67
ILE A  68
TYR A  94
ILE A 103
PHE A 111
 None
 0.53A 3uqbA-6b4pA:
19.8		 3uqbA-6b4pA:
32.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 8 TYR A  38
VAL A  67
ILE A  68
TYR A  94
ILE A  99
 None
 1.49A 3uqbA-6b4pA:
19.8		 3uqbA-6b4pA:
32.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.61A 3vawA-6b4pA:
19.1		 3vawA-6b4pA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 12 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.36A 4drhA-6b4pA:
19.2		 4drhA-6b4pA:
45.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 12 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.65A 4drhA-6b4pA:
19.2		 4drhA-6b4pA:
45.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 12 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.36A 4drhD-6b4pA:
19.3		 4drhD-6b4pA:
45.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 12 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.62A 4drhD-6b4pA:
19.3		 4drhD-6b4pA:
45.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 11 TYR A  38
ASP A  49
ARG A  54
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.84A 4driA-6b4pA:
21.3		 4driA-6b4pA:
45.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 11 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.48A 4driA-6b4pA:
21.3		 4driA-6b4pA:
45.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.61A 4driA-6b4pA:
21.3		 4driA-6b4pA:
45.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 11 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.72A 4drjA-6b4pA:
21.1		 4drjA-6b4pA:
42.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.74A 4dz2A-6b4pA:
19.9
4dz2B-6b4pA:
19.9		 4dz2A-6b4pA:
49.57
4dz2B-6b4pA:
49.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.74A 4dz2A-6b4pA:
19.9
4dz2B-6b4pA:
19.9		 4dz2A-6b4pA:
49.57
4dz2B-6b4pA:
49.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 10 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.68A 4dz3A-6b4pA:
20.2		 4dz3A-6b4pA:
49.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 10 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.63A 4dz3B-6b4pA:
15.0		 4dz3B-6b4pA:
49.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 10 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.65A 4laxA-6b4pA:
21.3		 4laxA-6b4pA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		4 / 8 PHE A  48
SER A 107
ALA A  93
TYR A  94
 None
 1.14A 4lv9A-6b4pA:
undetectable
4lv9B-6b4pA:
undetectable		 4lv9A-6b4pA:
15.50
4lv9B-6b4pA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		4 / 7 TYR A  94
PHE A  48
SER A 107
ALA A  93
 None
 1.14A 4lv9A-6b4pA:
undetectable
4lv9B-6b4pA:
undetectable		 4lv9A-6b4pA:
15.50
4lv9B-6b4pA:
15.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 12 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.58A 4nnrA-6b4pA:
15.3
4nnrB-6b4pA:
15.4		 4nnrA-6b4pA:
40.15
4nnrB-6b4pA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 10 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TYR A  94
ILE A 103
PHE A 111
 None
 0.46A 4nnrB-6b4pA:
15.4		 4nnrB-6b4pA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 10 TYR A  38
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.42A 4nnrB-6b4pA:
15.4		 4nnrB-6b4pA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 10 TYR A  38
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.58A 4nnrB-6b4pA:
15.4		 4nnrB-6b4pA:
40.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 10 TYR A  38
ASP A  49
ILE A  68
TYR A  94
PHE A 111
 None
 0.41A 4odoA-6b4pA:
11.3		 4odoA-6b4pA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 10 TYR A  38
ASP A  49
ILE A  68
TYR A  94
PHE A 111
 None
 0.40A 4odoB-6b4pA:
10.9		 4odoB-6b4pA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 10 TYR A  38
ASP A  49
ILE A  68
TYR A  94
PHE A 111
 None
 0.39A 4odoC-6b4pA:
10.8		 4odoC-6b4pA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 11 TYR A  38
ASP A  49
ILE A  68
TYR A  94
PHE A 111
 None
 0.42A 4odrA-6b4pA:
12.6
4odrB-6b4pA:
12.5		 4odrA-6b4pA:
22.92
4odrB-6b4pA:
22.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 10 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.68A 4qt2A-6b4pA:
21.9		 4qt2A-6b4pA:
44.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 10 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.49A 4qt2A-6b4pA:
21.9		 4qt2A-6b4pA:
44.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 10 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.69A 4qt3A-6b4pA:
20.1		 4qt3A-6b4pA:
40.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 10 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.48A 4qt3A-6b4pA:
20.1		 4qt3A-6b4pA:
40.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 12 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
PHE A 111
 None
 0.78A 5b8iC-6b4pA:
18.1		 5b8iC-6b4pA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 12 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TYR A  94
ILE A 103
PHE A 111
 None
 0.70A 5b8iC-6b4pA:
18.1		 5b8iC-6b4pA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 12 TYR A  38
ASP A  49
ARG A  54
VAL A  67
ILE A  68
TYR A  94
LEU A 102
ILE A 103
PHE A 111
 None
 0.73A 5b8iC-6b4pA:
18.1		 5b8iC-6b4pA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 11 TYR A  38
ASP A  49
VAL A  67
ILE A  68
TRP A  71
ILE A 103
PHE A 111
 None
 0.68A 5d75A-6b4pA:
18.6		 5d75A-6b4pA:
37.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 11 TYR A  38
ASP A  49
VAL A  67
ILE A  68
TYR A  94
ILE A 103
PHE A 111
 None
 0.45A 5d75A-6b4pA:
18.6		 5d75A-6b4pA:
37.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 11 TYR A  38
ASP A  49
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.62A 5gpgA-6b4pA:
19.4		 5gpgA-6b4pA:
37.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 12 TYR A  38
ASP A  49
PHE A  58
GLU A  66
VAL A  67
ILE A  68
TYR A  94
ILE A 103
PHE A 111
 None
 0.73A 5hkgA-6b4pA:
19.2		 5hkgA-6b4pA:
37.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
PHE A 111
 None
 0.60A 5huaA-6b4pA:
21.5		 5huaA-6b4pA:
43.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 11 TYR A  38
ASP A  49
ARG A  54
VAL A  67
ILE A  68
TYR A  94
LEU A 102
PHE A 111
 None
 0.59A 5huaA-6b4pA:
21.5		 5huaA-6b4pA:
43.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.32A 5hw8A-6b4pA:
17.6
5hw8D-6b4pA:
17.8		 5hw8A-6b4pA:
37.68
5hw8D-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TYR A  94
ILE A 103
 None
 0.63A 5hw8A-6b4pA:
17.6
5hw8D-6b4pA:
17.8		 5hw8A-6b4pA:
37.68
5hw8D-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
TRP A  71
TYR A  94
ILE A  99
 None
 1.40A 5hw8B-6b4pA:
17.9		 5hw8B-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
TRP A  71
TYR A  94
ILE A  99
ILE A 103
PHE A 111
 None
 0.66A 5hw8B-6b4pA:
17.9		 5hw8B-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		6 / 11 TYR A  38
PHE A  58
TRP A  71
ILE A  99
ILE A 103
PHE A 111
 None
 1.32A 5hw8B-6b4pA:
17.9		 5hw8B-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 10 TYR A  38
ASP A  49
ARG A  54
VAL A  67
ILE A  68
TRP A  71
TYR A  94
LEU A 109
PHE A 111
 None
 0.62A 5hw8C-6b4pA:
17.7
5hw8H-6b4pA:
14.9		 5hw8C-6b4pA:
37.68
5hw8H-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
PHE A 111
 None
 0.60A 5hw8D-6b4pA:
17.8		 5hw8D-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TYR A  94
ILE A 103
PHE A 111
 None
 0.56A 5hw8D-6b4pA:
17.8		 5hw8D-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
PHE A 111
 None
 0.62A 5hw8E-6b4pA:
17.8		 5hw8E-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TYR A  94
ILE A  99
PHE A 111
 None
 0.55A 5hw8E-6b4pA:
17.8		 5hw8E-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TYR A  94
ILE A 103
 None
 1.46A 5hw8E-6b4pA:
17.8		 5hw8E-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 11 TYR A  38
PHE A  58
TRP A  71
ILE A  99
PHE A 111
 None
 1.01A 5hw8E-6b4pA:
17.8		 5hw8E-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 12 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TYR A  94
ILE A  99
PHE A 111
 None
 0.55A 5hw8B-6b4pA:
17.9
5hw8F-6b4pA:
14.4
5hw8G-6b4pA:
17.2		 5hw8B-6b4pA:
37.68
5hw8F-6b4pA:
37.68
5hw8G-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 12 TYR A  38
PHE A  58
TRP A  71
ILE A  99
PHE A 111
 None
 1.00A 5hw8B-6b4pA:
17.9
5hw8F-6b4pA:
14.4
5hw8G-6b4pA:
17.2		 5hw8B-6b4pA:
37.68
5hw8F-6b4pA:
37.68
5hw8G-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 12 TYR A  38
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
PHE A 111
 None
 0.60A 5hw8B-6b4pA:
17.9
5hw8F-6b4pA:
14.4
5hw8G-6b4pA:
17.2		 5hw8B-6b4pA:
37.68
5hw8F-6b4pA:
37.68
5hw8G-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		8 / 11 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.40A 5hw8G-6b4pA:
17.2		 5hw8G-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
PHE A 111
 None
 0.58A 5hw8G-6b4pA:
17.2		 5hw8G-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TYR A  94
ILE A  99
ILE A 103
PHE A 111
 None
 0.52A 5hw8G-6b4pA:
17.2		 5hw8G-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		7 / 8 TYR A  38
ASP A  49
PHE A  58
VAL A  67
ILE A  68
TRP A  71
PHE A 111
 None
 0.67A 5hw8H-6b4pA:
14.9		 5hw8H-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		5 / 8 TYR A  38
PHE A  58
TRP A  71
ILE A  99
PHE A 111
 None
 1.11A 5hw8H-6b4pA:
14.9		 5hw8H-6b4pA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.42A 5hwcA-6b4pA:
19.4		 5hwcA-6b4pA:
43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 11 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.57A 5hwcA-6b4pA:
19.4		 5hwcA-6b4pA:
43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 12 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.73A 6mkeA-6b4pA:
24.7
6mkeD-6b4pA:
24.3		 6mkeA-6b4pA:
100.00
6mkeD-6b4pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 12 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.59A 6mkeB-6b4pA:
24.8
6mkeC-6b4pA:
24.8		 6mkeB-6b4pA:
100.00
6mkeC-6b4pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		4 / 4 ASP A  49
ILE A  99
PRO A 100
LEU A 102
 None
 1.13A 6mkeB-6b4pA:
24.8		 6mkeB-6b4pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 10 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.37A 6mkeC-6b4pA:
24.8		 6mkeC-6b4pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 10 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.48A 6mkeC-6b4pA:
24.8		 6mkeC-6b4pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		4 / 4 ASP A  49
ILE A  99
PRO A 100
LEU A 102
 None
 1.15A 6mkeA-6b4pA:
24.7		 6mkeA-6b4pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		9 / 10 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A  99
 None
 1.47A 6mkeD-6b4pA:
24.3		 6mkeD-6b4pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 6b4p PEPTIDYLPROLYL
ISOMERASE
(Naegleria
fowleri) 		10 / 10 TYR A  38
ASP A  49
ARG A  54
PHE A  58
VAL A  67
ILE A  68
TRP A  71
TYR A  94
ILE A 103
PHE A 111
 None
 0.51A 6mkeD-6b4pA:
24.3		 6mkeD-6b4pA:
100.00