SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 6b57 TUDOR AND KH
DOMAIN-CONTAINING
PROTEIN
(Homo
sapiens) 		4 / 8 GLY A 395
ASN A 394
TRP A 322
TYR A 387
 None
 1.12A 3ccfA-6b57A:
undetectable		 3ccfA-6b57A:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 6b57 TUDOR AND KH
DOMAIN-CONTAINING
PROTEIN
(Homo
sapiens) 		5 / 11 ARG A 512
VAL A 389
ILE A 359
GLY A 357
VAL A 356
 None
None
None
UNX  A 601 ( 4.1A)
None
 0.88A 3oxvD-6b57A:
undetectable		 3oxvD-6b57A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 6b57 TUDOR AND KH
DOMAIN-CONTAINING
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 451
VAL A 312
GLU A 485
ALA A 492
GLY A 490
 None
 1.02A 5uxdB-6b57A:
undetectable		 5uxdB-6b57A:
22.82