SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b5c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		3 / 3 LEU A 389
SER A 416
ASN A 422
 None
 0.67A 1bx4A-6b5cA:
undetectable		 1bx4A-6b5cA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		4 / 5 ARG A 196
ALA A 193
ASP A 189
GLU A 192
 None
 1.30A 2xrzA-6b5cA:
undetectable		 2xrzA-6b5cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		5 / 12 LEU A 245
ALA A 356
VAL A 354
PHE A 293
LEU A 194
 None
 1.18A 3b0wA-6b5cA:
undetectable		 3b0wA-6b5cA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		6 / 10 VAL A 272
PHE A 305
ILE A 364
LEU A 332
VAL A 328
VAL A 289
 None
 1.42A 3gwxA-6b5cA:
undetectable		 3gwxA-6b5cA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		4 / 6 LEU A 380
SER A 416
TYR A 415
ALA A 418
 None
 1.13A 3rd0A-6b5cA:
undetectable		 3rd0A-6b5cA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		5 / 12 LEU A 333
THR A 358
ALA A 356
VAL A 354
ILE A 306
 None
 1.16A 4x1kD-6b5cA:
undetectable		 4x1kD-6b5cA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		5 / 12 LEU A 333
LEU A 368
THR A 358
ALA A 356
VAL A 354
 None
 1.02A 4x1yB-6b5cA:
undetectable		 4x1yB-6b5cA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		5 / 12 LEU A 333
LEU A 368
THR A 358
ALA A 356
VAL A 354
 None
 0.97A 4x1yD-6b5cA:
undetectable		 4x1yD-6b5cA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		5 / 11 LEU A 333
LEU A 368
THR A 358
ALA A 356
VAL A 354
 None
 0.88A 4x20D-6b5cA:
undetectable		 4x20D-6b5cA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		5 / 11 LEU A 333
THR A 358
ALA A 356
VAL A 354
ILE A 306
 None
 1.15A 4x20D-6b5cA:
undetectable		 4x20D-6b5cA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		5 / 12 ILE A 403
LEU A 394
GLU A 462
PHE A 461
GLY A 459
 None
 1.13A 5l6eA-6b5cA:
undetectable		 5l6eA-6b5cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		4 / 4 LEU A 355
MET A 336
ILE A 376
LEU A 372
 None
 1.27A 5nfpA-6b5cA:
undetectable		 5nfpA-6b5cA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		5 / 12 THR A 255
SER A 273
SER A 275
SER A 274
ASN A 359
 None
 1.40A 6h7jA-6b5cA:
undetectable		 6h7jA-6b5cA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 6b5c KATANIN P60
ATPASE-CONTAINING
SUBUNIT A-LIKE 1
(Homo
sapiens) 		5 / 12 THR A 255
SER A 273
SER A 275
SER A 274
ASN A 359
 None
 1.40A 6h7jB-6b5cA:
undetectable		 6h7jB-6b5cA:
19.05