SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b5q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)
6b5q DCN1-LIKE PROTEIN 1
(Homo
sapiens)
4 / 7 LEU A  93
LEU A 103
MET A 126
TYR A  72
None
1.07A 2w8yA-6b5qA:
undetectable
2w8yA-6b5qA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)
6b5q DCN1-LIKE PROTEIN 1
(Homo
sapiens)
5 / 12 ALA A  98
VAL A 102
GLN A 114
GLU A 121
TYR A 181
None
1.49A 4zj8A-6b5qA:
undetectable
4zj8A-6b5qA:
8.62