SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b5v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 8 PHE A 537
PHE A 504
LEU A 568
MET A 570
 None
 1.18A 1x8vA-6b5vA:
0.5		 1x8vA-6b5vA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		5 / 12 ILE A 204
LEU A 203
HIS A 258
ALA A 247
LEU A 232
 None
 1.24A 2a58A-6b5vA:
undetectable
2a58B-6b5vA:
undetectable		 2a58A-6b5vA:
21.94
2a58B-6b5vA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		5 / 12 ILE A 204
LEU A 203
HIS A 258
ALA A 247
LEU A 232
 None
 1.25A 2a58B-6b5vA:
undetectable
2a58C-6b5vA:
undetectable		 2a58B-6b5vA:
21.94
2a58C-6b5vA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		5 / 12 ILE A 204
LEU A 203
HIS A 258
ALA A 247
LEU A 232
 None
 1.24A 2a58D-6b5vA:
undetectable
2a58E-6b5vA:
undetectable		 2a58D-6b5vA:
21.94
2a58E-6b5vA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		5 / 10 ALA A 141
LEU A  98
LEU A  83
LEU A 136
ARG A 139
 None
 1.17A 2ceoB-6b5vA:
undetectable		 2ceoB-6b5vA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 7 THR A 311
PRO A 312
VAL A 313
GLU A 309
 None
 0.96A 2v2gA-6b5vA:
undetectable
2v2gB-6b5vA:
undetectable		 2v2gA-6b5vA:
undetectable
2v2gB-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 7 THR A 311
PRO A 312
VAL A 313
GLU A 309
 None
 1.00A 2v2gA-6b5vA:
undetectable
2v2gB-6b5vA:
undetectable		 2v2gA-6b5vA:
undetectable
2v2gB-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 7 THR A 311
PRO A 312
VAL A 313
GLU A 309
 None
 1.00A 2v2gC-6b5vA:
undetectable
2v2gD-6b5vA:
undetectable		 2v2gC-6b5vA:
undetectable
2v2gD-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 7 THR A 311
PRO A 312
VAL A 313
GLU A 309
 None
 1.02A 2v2gC-6b5vA:
undetectable
2v2gD-6b5vA:
undetectable		 2v2gC-6b5vA:
undetectable
2v2gD-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 8 THR A 311
PRO A 312
VAL A 313
GLU A 309
 None
 1.00A 2v32C-6b5vA:
undetectable
2v32D-6b5vA:
undetectable		 2v32C-6b5vA:
undetectable
2v32D-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 8 THR A 311
PRO A 312
VAL A 313
GLU A 309
 None
 0.98A 2v32C-6b5vA:
undetectable
2v32D-6b5vA:
undetectable		 2v32C-6b5vA:
undetectable
2v32D-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 7 THR A 311
PRO A 312
VAL A 313
GLU A 309
 None
 0.98A 2v41E-6b5vA:
undetectable
2v41F-6b5vA:
undetectable		 2v41E-6b5vA:
undetectable
2v41F-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 7 THR A 311
PRO A 312
VAL A 313
GLU A 309
 None
 1.04A 2v41E-6b5vA:
undetectable
2v41F-6b5vA:
undetectable		 2v41E-6b5vA:
undetectable
2v41F-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		5 / 10 ALA A 141
LEU A  98
LEU A  83
LEU A 136
ARG A 139
 None
 1.15A 2xn7A-6b5vA:
undetectable
2xn7B-6b5vA:
undetectable		 2xn7A-6b5vA:
15.05
2xn7B-6b5vA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 8 VAL A 143
VAL A 125
ILE A 189
VAL A 199
 None
 0.87A 3hjoB-6b5vA:
undetectable		 3hjoB-6b5vA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		5 / 12 TYR A 467
GLY A 476
LEU A 475
ALA A 595
LEU A 421
 None
 1.00A 3vywA-6b5vA:
undetectable		 3vywA-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		5 / 12 TYR A 467
GLY A 476
LEU A 475
ALA A 595
LEU A 421
 None
 0.99A 3vywD-6b5vA:
undetectable		 3vywD-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 6 ILE A 183
LEU A 182
ARG A 190
THR A 198
 None
 1.04A 3wg7A-6b5vA:
undetectable
3wg7J-6b5vA:
undetectable		 3wg7A-6b5vA:
undetectable
3wg7J-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 5 VAL A 179
ARG A 180
GLU A 177
LEU A 218
 None
 1.41A 4hojA-6b5vA:
undetectable		 4hojA-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		5 / 12 PHE A 468
ALA A 469
PHE A 329
LEU A 332
GLY A 422
 None
 1.15A 4kykA-6b5vA:
undetectable
4kykB-6b5vA:
undetectable		 4kykA-6b5vA:
19.21
4kykB-6b5vA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		5 / 12 LEU A 132
ALA A 135
THR A  81
ALA A 120
ALA A 124
 None
 1.11A 4x1iB-6b5vA:
undetectable		 4x1iB-6b5vA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 6 ILE A 183
LEU A 182
ARG A 190
THR A 198
 None
 1.05A 5b1aN-6b5vA:
undetectable
5b1aW-6b5vA:
undetectable		 5b1aN-6b5vA:
undetectable
5b1aW-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		3 / 3 THR A 198
HIS A 201
ASN A 237
 None
 0.94A 5n4tA-6b5vA:
undetectable		 5n4tA-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		5 / 12 GLU A 104
LEU A  61
LEU A  65
ALA A 101
LEU A  83
 None
 1.21A 5nd7B-6b5vA:
undetectable		 5nd7B-6b5vA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 5 MET A 126
TYR A 161
TYR A 162
GLY A 163
 None
 0.87A 5x7pA-6b5vA:
undetectable		 5x7pA-6b5vA:
5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 6 MET A 126
TYR A 161
TYR A 162
GLY A 163
 None
 0.91A 5x7pB-6b5vA:
undetectable		 5x7pB-6b5vA:
5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		5 / 11 ALA A 498
PHE A 504
THR A 533
ILE A 565
ALA A 566
 None
 0.81A 6h1lB-6b5vA:
undetectable		 6h1lB-6b5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5
(Oryctolagus
cuniculus) 		4 / 6 ILE A 183
LEU A 182
ARG A 190
THR A 198
 None
 0.85A 6nmfN-6b5vA:
undetectable
6nmfW-6b5vA:
undetectable		 6nmfN-6b5vA:
undetectable
6nmfW-6b5vA:
undetectable