SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		4 / 6 PHE A 291
ILE A 134
VAL A 132
PHE A 141
 None
 0.95A 2cizA-6b67A:
undetectable		 2cizA-6b67A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		5 / 12 GLY A  17
LEU A  22
LEU A  26
SER A  54
GLY A  45
 None
 1.00A 3g2oA-6b67A:
undetectable		 3g2oA-6b67A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		5 / 12 GLY A  17
LEU A  22
LEU A  26
SER A  54
GLY A  45
 None
 0.89A 3g2oB-6b67A:
undetectable		 3g2oB-6b67A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		3 / 3 GLN A  30
GLU A  11
LYS A   9
 None
 1.18A 3su9A-6b67A:
undetectable		 3su9A-6b67A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		5 / 12 ILE A 224
ILE A 134
ILE A 289
LEU A 288
VAL A 254
 None
 1.26A 3w68C-6b67A:
undetectable		 3w68C-6b67A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		4 / 5 GLN A 213
THR A 128
HIS A  62
LEU A 191
 None
 1.15A 4lvcC-6b67A:
undetectable		 4lvcC-6b67A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		5 / 10 VAL A  58
TYR A  59
GLY A 145
GLY A 131
ASP A  38
 None
 1.42A 4mmcA-6b67A:
undetectable		 4mmcA-6b67A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		4 / 8 ASP A  38
ASP A  60
GLU A 146
ASP A 243
 None
CA  A 302 ( 2.8A)
CA  A 303 ( 4.9A)
CA  A 303 (-2.5A)
 0.88A 4xjeA-6b67A:
undetectable		 4xjeA-6b67A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		4 / 8 ASP A  38
ASP A  60
GLU A 146
ASP A 243
 None
CA  A 302 ( 2.8A)
CA  A 303 ( 4.9A)
CA  A 303 (-2.5A)
 0.84A 5cfsA-6b67A:
undetectable		 5cfsA-6b67A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		4 / 6 ARG A  33
ASP A  60
GLY A  61
ASP A  38
 None
CA  A 302 ( 2.8A)
CA  A 301 (-4.2A)
None
 1.33A 5hp1C-6b67A:
undetectable		 5hp1C-6b67A:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		5 / 12 GLY A 149
HIS A 222
GLU A 225
SER A 135
ILE A 134
 None
 1.26A 5igvA-6b67A:
undetectable		 5igvA-6b67A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		5 / 9 VAL A 254
VAL A 286
LEU A 258
LEU A 264
CYH A 290
 None
 1.19A 6czmD-6b67A:
undetectable
6czmE-6b67A:
undetectable		 6czmD-6b67A:
undetectable
6czmE-6b67A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6b67 PROTEIN PHOSPHATASE
1A
(Homo
sapiens) 		5 / 10 VAL A 254
VAL A 286
LEU A 258
LEU A 264
CYH A 290
 None
 1.22A 6czmE-6b67A:
undetectable
6czmF-6b67A:
undetectable		 6czmE-6b67A:
undetectable
6czmF-6b67A:
undetectable