SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b6h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 6b6h DNA-DIRECTED RNA
POLYMERASE SUBUNIT
ALPHA
(Escherichia
coli) 		5 / 9 LEU I 260
LEU I 307
ILE I 303
LEU I 281
ILE I 278
 None
 1.24A 2f78B-6b6hI:
undetectable		 2f78B-6b6hI:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 6b6h DNA-DIRECTED RNA
POLYMERASE SUBUNIT
ALPHA
(Escherichia
coli) 		5 / 9 LEU I 260
LEU I 307
ILE I 303
LEU I 281
ILE I 278
 None
 1.20A 2f7aA-6b6hI:
undetectable		 2f7aA-6b6hI:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 6b6h DNA-DIRECTED RNA
POLYMERASE SUBUNIT
ALPHA
(Escherichia
coli) 		3 / 3 ASP I 280
THR I 292
PRO I 293
 None
 0.67A 3tkgD-6b6hI:
undetectable		 3tkgD-6b6hI:
24.76