SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b6l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A29_A_TFPA154_1 (CALMODULIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 10	GLU A 339 GLU A 340 ALA A 368 LEU A 372 GLU A 344	None	1.17A	1a29A-6b6lA: undetectable	1a29A-6b6lA: 11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DDR_A_MTXA200_1 (DIHYDROFOLATE REDUCTASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	6 / 12	ILE A 702 ALA A 739 LEU A 769 THR A 795 SER A 793 ILE A 794	None	1.39A	1ddrA-6b6lA: undetectable	1ddrA-6b6lA: 11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_C_ACTC3004_0 (BETA-CARBONIC ANHYDRASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 6	TYR A 485 ASP A 523 VAL A 520 GLY A 513	None	1.15A	1ekjC-6b6lA: undetectable 1ekjD-6b6lA: undetectable	1ekjC-6b6lA: 15.66 1ekjD-6b6lA: 15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FAP_A_RAPA108_1 (FK506-BINDING PROTEIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	GLN A 48 VAL A 126 ILE A 157 ILE A 118 ILE A 176	None	0.79A	1fapA-6b6lA: undetectable	1fapA-6b6lA: 11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GAH_A_ACRA497_2 (GLUCOAMYLASE-471)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 6	SER A 627 TRP A 576 ARG A 572 LEU A 559	None	1.16A	1gahA-6b6lA: undetectable	1gahA-6b6lA: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H1D_A_SAMA301_0 (CATECHOL-O-METHYLTRA NSFERASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	ASN A 163 GLY A 117 TYR A 119 ASN A 359 TYR A 138	None	1.43A	1h1dA-6b6lA: 1.3	1h1dA-6b6lA: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KGL_A_RTLA175_0 (CELLULAR RETINOL-BINDING PROTEIN TYPE I)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	SER A 502 PHE A 524 TYR A 478 GLY A 477 ILE A 497	None	1.28A	1kglA-6b6lA: 1.4	1kglA-6b6lA: 9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OT7_A_CHCA1001_1 (BILE ACID RECEPTOR)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	MET A 316 ILE A 521 PHE A 303 ILE A 419 TRP A 268	None	1.46A	1ot7A-6b6lA: undetectable	1ot7A-6b6lA: 15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RQP_B_SAMB500_1 (5'-FLUORO-5'-DEOXYAD ENOSINE SYNTHASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 8	PHE A 733 SER A 766 ARG A 723 ALA A 784	None	1.19A	1rqpC-6b6lA: undetectable	1rqpC-6b6lA: 17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVD_B_SAMB601_0 (CATECHOL-O-METHYLTRA NSFERASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	GLY A 557 PHE A 607 TYR A 570 ASP A 558 ARG A 572	None None None EDO A 802 (-3.6A) None	1.38A	2avdB-6b6lA: undetectable	2avdB-6b6lA: 14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CL5_A_SAMA1217_0 (CATECHOL O-METHYLTRANSFERASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	ASN A 163 GLY A 117 TYR A 119 ASN A 359 TYR A 138	None	1.48A	2cl5A-6b6lA: 2.3	2cl5A-6b6lA: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FXD_A_DR7A102_1 (POL PROTEIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 11	ILE A 735 GLY A 745 GLY A 331 ILE A 66 VAL A 770	None	1.01A	2fxdA-6b6lA: undetectable	2fxdA-6b6lA: 9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JB7_B_ACTB1169_0 (HYPOTHETICAL PROTEIN PAE2307)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	3 / 3	ARG A 484 ARG A 491 ARG A 495	None	1.05A	2jb7A-6b6lA: undetectable 2jb7B-6b6lA: undetectable 2jb7C-6b6lA: undetectable	2jb7A-6b6lA: 12.71 2jb7B-6b6lA: 12.71 2jb7C-6b6lA: 12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JB7_B_ACTB1169_0 (HYPOTHETICAL PROTEIN PAE2307)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	3 / 3	ARG A 491 ARG A 495 ARG A 484	None	1.12A	2jb7A-6b6lA: undetectable 2jb7B-6b6lA: undetectable 2jb7C-6b6lA: undetectable	2jb7A-6b6lA: 12.71 2jb7B-6b6lA: 12.71 2jb7C-6b6lA: 12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JB7_B_ACTB1169_0 (HYPOTHETICAL PROTEIN PAE2307)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	3 / 3	ARG A 495 ARG A 484 ARG A 491	None	1.07A	2jb7A-6b6lA: undetectable 2jb7B-6b6lA: undetectable 2jb7C-6b6lA: undetectable	2jb7A-6b6lA: 12.71 2jb7B-6b6lA: 12.71 2jb7C-6b6lA: 12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PNC_A_CLUA808_1 (COPPER AMINE OXIDASE, LIVER ISOZYME)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 7	TYR A 171 MET A 120 TYR A 138 HIS A 325	None	1.19A	2pncA-6b6lA: undetectable	2pncA-6b6lA: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V3D_B_NBVB1504_1 (GLUCOSYLCERAMIDASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 11	ASN A 425 GLU A 426 TYR A 480 GLU A 501 TRP A 526	None	0.83A	2v3dB-6b6lA: 14.1	2v3dB-6b6lA: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V7U_A_SAMA1299_0 (5'-FLUORO-5'-DEOXY ADENOSINE SYNTHETASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 8	PHE A 733 SER A 766 ARG A 723 ALA A 784	None	1.16A	2v7uA-6b6lA: undetectable	2v7uA-6b6lA: 17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W8Y_A_486A1000_2 (PROGESTERONE RECEPTOR)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 7	LEU A 366 ASN A 367 GLU A 340 LEU A 372	None	1.26A	2w8yA-6b6lA: undetectable	2w8yA-6b6lA: 15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_B_CHDB152_0 (ILEAL BILE ACID-BINDING PROTEIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	3 / 3	ASN A 235 HIS A 237 VAL A 239	None	0.76A	3elzB-6b6lA: undetectable	3elzB-6b6lA: 10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FPJ_A_SAMA301_1 (PUTATIVE UNCHARACTERIZED PROTEIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 6	GLY A 424 THR A 443 GLU A 426 GLU A 431	None	0.95A	3fpjA-6b6lA: undetectable	3fpjA-6b6lA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N62_A_MTLA870_0 (NITRIC OXIDE SYNTHASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 8	SER A 569 ARG A 565 PHE A 351 TRP A 576	EDO A 802 (-2.6A) EDO A 802 (-3.7A) EDO A 802 (-4.0A) None	1.25A	3n62A-6b6lA: undetectable	3n62A-6b6lA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NMU_F_SAMF228_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE NOP5/NOP56 RELATED PROTEIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	ALA A 364 GLU A 339 ASP A 326 ALA A 332 ASP A 116	None	1.36A	3nmuA-6b6lA: undetectable 3nmuF-6b6lA: undetectable	3nmuA-6b6lA: 18.63 3nmuF-6b6lA: 15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PGH_A_FLPA701_1 (CYCLOOXYGENASE-2)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	VAL A 782 LEU A 709 LEU A 769 GLY A 774 ALA A 739	None	1.26A	3pghA-6b6lA: undetectable	3pghA-6b6lA: 20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_B_SUEB1201_3 (NS3 PROTEASE, NS4A PROTEIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 5	SER A 357 ARG A 355 TYR A 498 VAL A 376	None	1.28A	3sufC-6b6lA: undetectable	3sufC-6b6lA: 13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFN_A_ROCA401_2 (HIV-1 PROTEASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 7	GLY A 666 ILE A 667 VAL A 626 VAL A 661	None	0.82A	3ufnB-6b6lA: undetectable	3ufnB-6b6lA: 7.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UY4_A_PAUA302_0 (PANTOTHENATE SYNTHETASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 8	ARG A 299 VAL A 278 ASP A 370 ARG A 453	None	1.15A	3uy4A-6b6lA: undetectable	3uy4A-6b6lA: 17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KF9_A_ACTA408_0 (GLUTATHIONE S-TRANSFERASE PROTEIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 6	THR A 587 PRO A 589 ARG A 764 PHE A 616	None	1.26A	4kf9A-6b6lA: undetectable	4kf9A-6b6lA: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M11_C_MXMC606_2 (PROSTAGLANDIN G/H SYNTHASE 2)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	3 / 3	LEU A 267 ARG A 299 MET A 420	None	0.91A	4m11C-6b6lA: undetectable	4m11C-6b6lA: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MX0_A_BCZA513_1 (NEURAMINIDASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	3 / 3	ARG A 411 ASP A 378 ARG A 178	None	0.99A	4mx0A-6b6lA: undetectable	4mx0A-6b6lA: 17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PEV_B_ADNB501_1 (MEMBRANE LIPOPROTEIN FAMILY PROTEIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	SER A 562 GLY A 331 ASP A 326 PHE A 755 GLY A 745	None	1.33A	4pevB-6b6lA: undetectable	4pevB-6b6lA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UYM_A_VORA590_1 (14-ALPHA STEROL DEMETHYLASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 7	PHE A 469 ALA A 457 SER A 422 LEU A 442	None	0.95A	4uymA-6b6lA: undetectable	4uymA-6b6lA: 18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECN_A_LEUA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 7	ALA A 465 THR A 466 VAL A 436 LYS A 430	None	1.18A	5ecnA-6b6lA: undetectable	5ecnA-6b6lA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FHR_B_SAMB303_0 (CATECHOL O-METHYLTRANSFERASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	ASN A 163 GLY A 117 TYR A 119 ASN A 359 TYR A 138	None	1.48A	5fhrB-6b6lA: undetectable	5fhrB-6b6lA: 13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L8D_B_ACTB601_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	3 / 3	THR A 139 PRO A 360 ASP A 378	None	0.84A	5l8dB-6b6lA: undetectable	5l8dB-6b6lA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MM4_B_TA1B501_1 (TUBULIN BETA CHAIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 10	GLU A 691 LEU A 639 HIS A 665 ALA A 687 THR A 683	None	1.43A	5mm4B-6b6lA: undetectable	5mm4B-6b6lA: 7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWU_B_ACTB601_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	3 / 3	THR A 139 PRO A 360 ASP A 378	None	0.84A	5mwuB-6b6lA: undetectable	5mwuB-6b6lA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UIG_A_EDTA501_0 (ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 6	ASN A 73 THR A 72 ILE A 752 GLU A 753	None	1.03A	5uigA-6b6lA: undetectable	5uigA-6b6lA: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUO_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 8	SER A 569 ARG A 565 PHE A 351 TRP A 576	EDO A 802 (-2.6A) EDO A 802 (-3.7A) EDO A 802 (-4.0A) None	1.31A	5vuoB-6b6lA: undetectable	5vuoB-6b6lA: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AN0_A_HISA520_0 (HISTIDINOL DEHYDROGENASE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	4 / 6	GLU A 344 LYS A 342 ARG A 337 GLU A 339	None	1.21A	6an0A-6b6lA: undetectable	6an0A-6b6lA: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6I0Y_A_TRPA3001_0 (23S RIBOSOMAL RNA TRYPTOPHANASE OPERON LEADER PEPTIDE)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	3 / 3	TRP A 421 ILE A 377 ASP A 378	None	0.57A	6i0y7-6b6lA: undetectable	6i0y7-6b6lA: 4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6J21_A_GBQA1201_0 (SUBSTANCE-P RECEPTOR,ENDOLYSIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	ASN A 352 ILE A 521 ILE A 301 VAL A 475 PHE A 524	None	1.03A	6j21A-6b6lA: undetectable	6j21A-6b6lA: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6J21_A_GBQA1201_0 (SUBSTANCE-P RECEPTOR,ENDOLYSIN)	6b6l	GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN (Bacteroides cellulosilyticus)	5 / 12	ASN A 352 ILE A 521 VAL A 514 ILE A 301 PHE A 524	None	1.18A	6j21A-6b6lA: undetectable	6j21A-6b6lA: 19.85

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A29_A_TFPA154_1","CALMODULIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"GLU A 339;GLU A 340;ALA A 368;LEU A 372;GLU A 344","None","1.17A","1a29A-6b6lA:undetectable","1a29A-6b6lA:11.50"],["1DDR_A_MTXA200_1","DIHYDROFOLATE REDUCTASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",6,"ILE A 702;ALA A 739;LEU A 769;THR A 795;SER A 793;ILE A 794","None","1.39A","1ddrA-6b6lA:undetectable","1ddrA-6b6lA:11.64"],["1EKJ_C_ACTC3004_0","BETA-CARBONIC ANHYDRASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"TYR A 485;ASP A 523;VAL A 520;GLY A 513","None","1.15A","1ekjC-6b6lA:undetectable;1ekjD-6b6lA:undetectable","1ekjC-6b6lA:15.66;1ekjD-6b6lA:15.66"],["1FAP_A_RAPA108_1","FK506-BINDING PROTEIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"GLN A  48;VAL A 126;ILE A 157;ILE A 118;ILE A 176","None","0.79A","1fapA-6b6lA:undetectable","1fapA-6b6lA:11.30"],["1GAH_A_ACRA497_2","GLUCOAMYLASE-471","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"SER A 627;TRP A 576;ARG A 572;LEU A 559","None","1.16A","1gahA-6b6lA:undetectable","1gahA-6b6lA:20.43"],["1H1D_A_SAMA301_0","CATECHOL-O-METHYLTRANSFERASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"ASN A 163;GLY A 117;TYR A 119;ASN A 359;TYR A 138","None","1.43A","1h1dA-6b6lA:1.3","1h1dA-6b6lA:13.45"],["1KGL_A_RTLA175_0","CELLULAR RETINOL-BINDING PROTEIN TYPE I","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"SER A 502;PHE A 524;TYR A 478;GLY A 477;ILE A 497","None","1.28A","1kglA-6b6lA:1.4","1kglA-6b6lA:9.97"],["1OT7_A_CHCA1001_1","BILE ACID RECEPTOR","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"MET A 316;ILE A 521;PHE A 303;ILE A 419;TRP A 268","None","1.46A","1ot7A-6b6lA:undetectable","1ot7A-6b6lA:15.27"],["1RQP_B_SAMB500_1","5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"PHE A 733;SER A 766;ARG A 723;ALA A 784","None","1.19A","1rqpC-6b6lA:undetectable","1rqpC-6b6lA:17.30"],["2AVD_B_SAMB601_0","CATECHOL-O-METHYLTRANSFERASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"GLY A 557;PHE A 607;TYR A 570;ASP A 558;ARG A 572","None;None;None;EDO A 802 (-3.6A);None","1.38A","2avdB-6b6lA:undetectable","2avdB-6b6lA:14.03"],["2CL5_A_SAMA1217_0","CATECHOL O-METHYLTRANSFERASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"ASN A 163;GLY A 117;TYR A 119;ASN A 359;TYR A 138","None","1.48A","2cl5A-6b6lA:2.3","2cl5A-6b6lA:13.45"],["2FXD_A_DR7A102_1","POL PROTEIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"ILE A 735;GLY A 745;GLY A 331;ILE A  66;VAL A 770","None","1.01A","2fxdA-6b6lA:undetectable","2fxdA-6b6lA:9.41"],["2JB7_B_ACTB1169_0","HYPOTHETICAL PROTEIN PAE2307","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",3,"ARG A 484;ARG A 491;ARG A 495","None","1.05A","2jb7A-6b6lA:undetectable;2jb7B-6b6lA:undetectable;2jb7C-6b6lA:undetectable","2jb7A-6b6lA:12.71;2jb7B-6b6lA:12.71;2jb7C-6b6lA:12.71"],["2JB7_B_ACTB1169_0","HYPOTHETICAL PROTEIN PAE2307","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",3,"ARG A 491;ARG A 495;ARG A 484","None","1.12A","2jb7A-6b6lA:undetectable;2jb7B-6b6lA:undetectable;2jb7C-6b6lA:undetectable","2jb7A-6b6lA:12.71;2jb7B-6b6lA:12.71;2jb7C-6b6lA:12.71"],["2JB7_B_ACTB1169_0","HYPOTHETICAL PROTEIN PAE2307","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",3,"ARG A 495;ARG A 484;ARG A 491","None","1.07A","2jb7A-6b6lA:undetectable;2jb7B-6b6lA:undetectable;2jb7C-6b6lA:undetectable","2jb7A-6b6lA:12.71;2jb7B-6b6lA:12.71;2jb7C-6b6lA:12.71"],["2PNC_A_CLUA808_1","COPPER AMINE OXIDASE, LIVER ISOZYME","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"TYR A 171;MET A 120;TYR A 138;HIS A 325","None","1.19A","2pncA-6b6lA:undetectable","2pncA-6b6lA:21.47"],["2V3D_B_NBVB1504_1","GLUCOSYLCERAMIDASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"ASN A 425;GLU A 426;TYR A 480;GLU A 501;TRP A 526","None","0.83A","2v3dB-6b6lA:14.1","2v3dB-6b6lA:20.92"],["2V7U_A_SAMA1299_0","5'-FLUORO-5'-DEOXY ADENOSINE SYNTHETASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"PHE A 733;SER A 766;ARG A 723;ALA A 784","None","1.16A","2v7uA-6b6lA:undetectable","2v7uA-6b6lA:17.17"],["2W8Y_A_486A1000_2","PROGESTERONE RECEPTOR","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"LEU A 366;ASN A 367;GLU A 340;LEU A 372","None","1.26A","2w8yA-6b6lA:undetectable","2w8yA-6b6lA:15.16"],["3ELZ_B_CHDB152_0","ILEAL BILE ACID-BINDING PROTEIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",3,"ASN A 235;HIS A 237;VAL A 239","None","0.76A","3elzB-6b6lA:undetectable","3elzB-6b6lA:10.79"],["3FPJ_A_SAMA301_1","PUTATIVE UNCHARACTERIZED PROTEIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"GLY A 424;THR A 443;GLU A 426;GLU A 431","None","0.95A","3fpjA-6b6lA:undetectable","3fpjA-6b6lA:16.43"],["3N62_A_MTLA870_0","NITRIC OXIDE SYNTHASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"SER A 569;ARG A 565;PHE A 351;TRP A 576","EDO A 802 (-2.6A);EDO A 802 (-3.7A);EDO A 802 (-4.0A);None","1.25A","3n62A-6b6lA:undetectable","3n62A-6b6lA:18.53"],["3NMU_F_SAMF228_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE;NOP5\/NOP56 RELATED PROTEIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"ALA A 364;GLU A 339;ASP A 326;ALA A 332;ASP A 116","None","1.36A","3nmuA-6b6lA:undetectable;3nmuF-6b6lA:undetectable","3nmuA-6b6lA:18.63;3nmuF-6b6lA:15.08"],["3PGH_A_FLPA701_1","CYCLOOXYGENASE-2","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"VAL A 782;LEU A 709;LEU A 769;GLY A 774;ALA A 739","None","1.26A","3pghA-6b6lA:undetectable","3pghA-6b6lA:20.08"],["3SUF_B_SUEB1201_3","NS3 PROTEASE, NS4A PROTEIN;NS3 PROTEASE, NS4A PROTEIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"SER A 357;ARG A 355;TYR A 498;VAL A 376","None","1.28A","3sufC-6b6lA:undetectable","3sufC-6b6lA:13.92"],["3UFN_A_ROCA401_2","HIV-1 PROTEASE;HIV-1 PROTEASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"GLY A 666;ILE A 667;VAL A 626;VAL A 661","None","0.82A","3ufnB-6b6lA:undetectable","3ufnB-6b6lA:7.73"],["3UY4_A_PAUA302_0","PANTOTHENATE SYNTHETASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"ARG A 299;VAL A 278;ASP A 370;ARG A 453","None","1.15A","3uy4A-6b6lA:undetectable","3uy4A-6b6lA:17.56"],["4KF9_A_ACTA408_0","GLUTATHIONE S-TRANSFERASE PROTEIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"THR A 587;PRO A 589;ARG A 764;PHE A 616","None","1.26A","4kf9A-6b6lA:undetectable","4kf9A-6b6lA:18.94"],["4M11_C_MXMC606_2","PROSTAGLANDIN G\/H SYNTHASE 2","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",3,"LEU A 267;ARG A 299;MET A 420","None","0.91A","4m11C-6b6lA:undetectable","4m11C-6b6lA:20.94"],["4MX0_A_BCZA513_1","NEURAMINIDASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",3,"ARG A 411;ASP A 378;ARG A 178","None","0.99A","4mx0A-6b6lA:undetectable","4mx0A-6b6lA:17.81"],["4PEV_B_ADNB501_1","MEMBRANE LIPOPROTEIN FAMILY PROTEIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"SER A 562;GLY A 331;ASP A 326;PHE A 755;GLY A 745","None","1.33A","4pevB-6b6lA:undetectable","4pevB-6b6lA:21.18"],["4UYM_A_VORA590_1","14-ALPHA STEROL DEMETHYLASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"PHE A 469;ALA A 457;SER A 422;LEU A 442","None","0.95A","4uymA-6b6lA:undetectable","4uymA-6b6lA:18.87"],["5ECN_A_LEUA602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"ALA A 465;THR A 466;VAL A 436;LYS A 430","None","1.18A","5ecnA-6b6lA:undetectable","5ecnA-6b6lA:21.26"],["5FHR_B_SAMB303_0","CATECHOL O-METHYLTRANSFERASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"ASN A 163;GLY A 117;TYR A 119;ASN A 359;TYR A 138","None","1.48A","5fhrB-6b6lA:undetectable","5fhrB-6b6lA:13.85"],["5L8D_B_ACTB601_0","NICKEL-BINDING PERIPLASMIC PROTEIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",3,"THR A 139;PRO A 360;ASP A 378","None","0.84A","5l8dB-6b6lA:undetectable","5l8dB-6b6lA:20.82"],["5MM4_B_TA1B501_1","TUBULIN BETA CHAIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"GLU A 691;LEU A 639;HIS A 665;ALA A 687;THR A 683","None","1.43A","5mm4B-6b6lA:undetectable","5mm4B-6b6lA:7.93"],["5MWU_B_ACTB601_0","NICKEL-BINDING PERIPLASMIC PROTEIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",3,"THR A 139;PRO A 360;ASP A 378","None","0.84A","5mwuB-6b6lA:undetectable","5mwuB-6b6lA:20.82"],["5UIG_A_EDTA501_0","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"ASN A  73;THR A  72;ILE A 752;GLU A 753","None","1.03A","5uigA-6b6lA:undetectable","5uigA-6b6lA:21.19"],["5VUO_B_MTLB805_0","NITRIC OXIDE SYNTHASE, BRAIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"SER A 569;ARG A 565;PHE A 351;TRP A 576","EDO A 802 (-2.6A);EDO A 802 (-3.7A);EDO A 802 (-4.0A);None","1.31A","5vuoB-6b6lA:undetectable","5vuoB-6b6lA:18.65"],["6AN0_A_HISA520_0","HISTIDINOL DEHYDROGENASE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",4,"GLU A 344;LYS A 342;ARG A 337;GLU A 339","None","1.21A","6an0A-6b6lA:undetectable","6an0A-6b6lA:20.61"],["6I0Y_A_TRPA3001_0","23S RIBOSOMAL RNA;TRYPTOPHANASE OPERON LEADER PEPTIDE","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",3,"TRP A 421;ILE A 377;ASP A 378","None","0.57A","6i0y7-6b6lA:undetectable","6i0y7-6b6lA:4.91"],["6J21_A_GBQA1201_0","SUBSTANCE-P RECEPTOR,ENDOLYSIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"ASN A 352;ILE A 521;ILE A 301;VAL A 475;PHE A 524","None","1.03A","6j21A-6b6lA:undetectable","6j21A-6b6lA:19.85"],["6J21_A_GBQA1201_0","SUBSTANCE-P RECEPTOR,ENDOLYSIN","6b6l","GLYCOSYL HYDROLASE FAMILY 2, SUGAR BINDING DOMAIN PROTEIN","Bacteroides cellulosilyticus",5,"ASN A 352;ILE A 521;VAL A 514;ILE A 301;PHE A 524","None","1.18A","6j21A-6b6lA:undetectable","6j21A-6b6lA:19.85"]]