SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 6b72 PROTEIN NEF
(Human
immunodeficiency
virus
1) 		4 / 4 GLY A 132
GLY A 130
THR A 128
LEU A 198
 None
 0.78A 3si7C-6b72A:
undetectable
3si7D-6b72A:
undetectable		 3si7C-6b72A:
undetectable
3si7D-6b72A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6b72 PROTEIN NEF
(Human
immunodeficiency
virus
1) 		3 / 3 ALA A  84
GLN A 125
THR A 138
 None
 0.75A 5n0oA-6b72A:
undetectable		 5n0oA-6b72A:
undetectable