SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b7j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 6b7j 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Vibrio
cholerae) 		3 / 3 TYR A  26
GLY A  19
PHE A  22
 None
 0.71A 2m2pB-6b7jA:
undetectable		 2m2pB-6b7jA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 6b7j 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Vibrio
cholerae) 		5 / 11 ARG A   5
ILE A  40
PHE A  93
LEU A  13
ASP A  12
 None
 1.02A 2q6hA-6b7jA:
undetectable		 2q6hA-6b7jA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 6b7j 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Vibrio
cholerae) 		5 / 12 ARG A   5
ILE A  40
PHE A  93
LEU A  13
ASP A  12
 None
 1.04A 2qb4A-6b7jA:
undetectable		 2qb4A-6b7jA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 6b7j 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Vibrio
cholerae) 		5 / 11 ARG A   5
ILE A  40
PHE A  93
LEU A  13
ASP A  12
 None
 1.02A 2qeiA-6b7jA:
undetectable		 2qeiA-6b7jA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 6b7j 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Vibrio
cholerae) 		5 / 11 ARG A   5
ILE A  40
PHE A  93
LEU A  13
ASP A  12
 None
 1.02A 2qjuA-6b7jA:
undetectable		 2qjuA-6b7jA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 6b7j 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Vibrio
cholerae) 		4 / 8 ASP A  64
LEU A  65
ASP A  38
ASP A  60
 None
 1.24A 3n2oC-6b7jA:
undetectable
3n2oD-6b7jA:
undetectable		 3n2oC-6b7jA:
14.83
3n2oD-6b7jA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 6b7j 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Vibrio
cholerae) 		5 / 12 SER A  16
GLY A  92
LEU A 161
ASP A 145
ILE A  55
 None
 1.08A 4pghD-6b7jA:
undetectable		 4pghD-6b7jA:
21.57