SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b7p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 1.08A 1c8lA-6b7pA:
undetectable		 1c8lA-6b7pA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 1.02A 1gfzA-6b7pA:
undetectable		 1gfzA-6b7pA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 6b7p SDED
(Legionella
pneumophila) 		4 / 7 SER A 157
GLU A 159
GLU A 160
GLU A 181
 None
 1.12A 1knyA-6b7pA:
undetectable
1knyB-6b7pA:
1.7		 1knyA-6b7pA:
16.74
1knyB-6b7pA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 6b7p SDED
(Legionella
pneumophila) 		5 / 11 LEU A   5
ALA A 287
VAL A   9
LEU A 117
GLN A 116
 None
 1.27A 1kt6A-6b7pA:
undetectable		 1kt6A-6b7pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 6b7p SDED
(Legionella
pneumophila) 		5 / 11 LEU A   5
ALA A 287
VAL A   9
LEU A 117
GLN A 116
 None
 1.24A 1kt7A-6b7pA:
undetectable		 1kt7A-6b7pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 1.03A 1l5qA-6b7pA:
undetectable		 1l5qA-6b7pA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 1.04A 1l5qB-6b7pA:
undetectable		 1l5qB-6b7pA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 0.99A 1l7xA-6b7pA:
undetectable		 1l7xA-6b7pA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 0.99A 1l7xB-6b7pA:
undetectable		 1l7xB-6b7pA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 6b7p SDED
(Legionella
pneumophila) 		4 / 7 TYR A  15
GLY A 122
ALA A 121
LEU A  21
 None
 0.83A 2wekB-6b7pA:
undetectable		 2wekB-6b7pA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 TYR A 232
ALA A 233
LEU A 236
ASN A 113
 None
 0.68A 3b6hB-6b7pA:
undetectable		 3b6hB-6b7pA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 TYR A 232
ALA A 233
LEU A 236
THR A  72
 None
 0.91A 3b6hB-6b7pA:
undetectable		 3b6hB-6b7pA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 1.01A 3dd1A-6b7pA:
undetectable		 3dd1A-6b7pA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 0.99A 3dd1B-6b7pA:
undetectable		 3dd1B-6b7pA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 1.04A 3ddsA-6b7pA:
undetectable		 3ddsA-6b7pA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 1.01A 3ddsB-6b7pA:
undetectable		 3ddsB-6b7pA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 1.02A 3ddwA-6b7pA:
undetectable		 3ddwA-6b7pA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 1.01A 3ddwB-6b7pA:
undetectable		 3ddwB-6b7pA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 6b7p SDED
(Legionella
pneumophila) 		5 / 9 ILE A 184
GLN A  89
ASP A 225
PHE A 221
LEU A 187
 None
 1.43A 3mjrA-6b7pA:
undetectable		 3mjrA-6b7pA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_C_NCAC302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 6b7p SDED
(Legionella
pneumophila) 		5 / 10 TYR A 232
TYR A  78
LEU A 298
ALA A 239
ALA A  70
 None
 1.06A 3rodC-6b7pA:
undetectable		 3rodC-6b7pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6b7p SDED
(Legionella
pneumophila) 		5 / 12 GLY A 293
CYH A 294
LEU A 236
LEU A 117
LEU A  10
 None
 1.33A 4emaA-6b7pA:
undetectable		 4emaA-6b7pA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 6b7p SDED
(Legionella
pneumophila) 		4 / 8 TYR A 133
VAL A 120
HIS A  67
LEU A 193
 None
 0.76A 4jtrA-6b7pA:
undetectable		 4jtrA-6b7pA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 6b7p SDED
(Legionella
pneumophila) 		5 / 11 GLU A 242
LEU A 193
VAL A 202
ILE A 213
LEU A 217
 None
 1.42A 4k37A-6b7pA:
undetectable		 4k37A-6b7pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME
KP18CYS PEPTIDE)		 6b7p SDED
(Legionella
pneumophila) 		5 / 12 GLU A 242
LEU A 193
VAL A 202
ILE A 213
LEU A 217
 None
 1.37A 4k38A-6b7pA:
undetectable
4k38D-6b7pA:
undetectable		 4k38A-6b7pA:
undetectable
4k38D-6b7pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 6b7p SDED
(Legionella
pneumophila) 		5 / 12 GLU A 242
LEU A 193
VAL A 202
ILE A 213
LEU A 217
 None
 1.33A 4k38B-6b7pA:
undetectable		 4k38B-6b7pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 6b7p SDED
(Legionella
pneumophila) 		4 / 7 ALA A  44
THR A  42
GLU A  33
HIS A  49
 None
 1.15A 5ecnA-6b7pA:
undetectable		 5ecnA-6b7pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_H_ADNH401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 6b7p SDED
(Legionella
pneumophila) 		5 / 9 GLY A 270
VAL A 269
MET A 230
ASN A 273
VAL A 274
 None
 1.05A 5lw1H-6b7pA:
undetectable		 5lw1H-6b7pA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 6b7p SDED
(Legionella
pneumophila) 		4 / 5 PRO A 180
GLY A 178
TYR A 183
VAL A  94
 None
 1.30A 5x80C-6b7pA:
undetectable
5x80D-6b7pA:
undetectable		 5x80C-6b7pA:
20.42
5x80D-6b7pA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 6b7p SDED
(Legionella
pneumophila) 		4 / 8 TYR A 232
THR A  75
CYH A 294
LEU A   5
 None
 1.42A 6cnjD-6b7pA:
undetectable
6cnjE-6b7pA:
undetectable		 6cnjD-6b7pA:
17.05
6cnjE-6b7pA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 6b7p SDED
(Legionella
pneumophila) 		4 / 6 TYR A  25
GLU A 126
CYH A 196
GLU A 242
 None
 1.08A 6mn5A-6b7pA:
undetectable		 6mn5A-6b7pA:
17.86