SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 6b7t GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		4 / 8 ASN A 200
ASN A 174
GLY A -11
LEU A   7
 None
 0.94A 1dzmA-6b7tA:
2.0		 1dzmA-6b7tA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 6b7t GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A 101
VAL A 142
ASN A 151
ILE A  44
PHE A  38
 None
GYS  A  96 ( 4.9A)
GYS  A  96 ( 3.6A)
None
None
 1.18A 3t3rB-6b7tA:
undetectable		 3t3rB-6b7tA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 6b7t GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A 101
VAL A 142
ASN A 151
ILE A  44
PHE A  38
 None
GYS  A  96 ( 4.9A)
GYS  A  96 ( 3.6A)
None
None
 1.22A 3t3rC-6b7tA:
undetectable		 3t3rC-6b7tA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 6b7t GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 10 PHE A 101
VAL A 142
ASN A 151
ILE A  44
PHE A  38
 None
GYS  A  96 ( 4.9A)
GYS  A  96 ( 3.6A)
None
None
 1.16A 3t3rD-6b7tA:
undetectable		 3t3rD-6b7tA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 6b7t GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		4 / 6 THR A 158
ASN A  53
GLY A  54
ASP A  51
 None
 1.20A 3w9tE-6b7tA:
undetectable		 3w9tE-6b7tA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 6b7t GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		4 / 7 ASP A  49
THR A 138
SER A  58
PHE A  57
 None
 1.01A 4ac9C-6b7tA:
undetectable		 4ac9C-6b7tA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6b7t GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		4 / 6 VAL A  85
LEU A  83
LEU A 155
PHE A 195
 None
None
None
GYS  A  96 ( 4.6A)
 0.90A 4o1zA-6b7tA:
undetectable		 4o1zA-6b7tA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)		 6b7t GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 12 HIS A -15
SER A -13
SER A -12
ASN A 179
HIS A -16
 None
None
GYS  A  96 ( 3.9A)
None
None
 1.39A 6chgC-6b7tA:
undetectable		 6chgC-6b7tA:
undetectable