SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b85'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)
6b85 TMHC4_R
(synthetic
construct)
3 / 3 TYR J 205
LYS J 190
LYS J 186
None
0.86A 5dbyA-6b85J:
undetectable
5dbyA-6b85J:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)
6b85 TMHC4_R
(synthetic
construct)
4 / 7 ASP J 181
ALA J 174
LEU J 177
TRP J 151
None
1.07A 5nwvA-6b85J:
undetectable
5nwvA-6b85J:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
6b85 TMHC4_R
(synthetic
construct)
4 / 9 LYS J   9
ILE J  10
ILE J  14
LEU J  17
None
0.64A 5vkqB-6b85J:
4.4
5vkqC-6b85J:
4.3
5vkqB-6b85J:
undetectable
5vkqC-6b85J:
undetectable