SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b92'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		4 / 7 LEU A 166
ALA A 169
LEU A 165
VAL A 158
 None
None
SAH  A 305 ( 4.6A)
None
 1.02A 1dvxB-6b92A:
undetectable		 1dvxB-6b92A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 1.04A 1hsgB-6b92A:
undetectable		 1hsgB-6b92A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		7 / 12 PRO A  77
ILE A 109
GLY A 110
GLY A 112
THR A 132
VAL A 134
ASN A 184
 SAH  A 305 ( 4.8A)
None
SAH  A 305 (-3.1A)
SAH  A 305 (-3.4A)
SAH  A 305 (-4.4A)
SAH  A 305 (-4.1A)
SAH  A 305 (-3.4A)
 0.71A 1nv8A-6b92A:
16.7		 1nv8A-6b92A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		4 / 6 VAL A  89
LEU A  92
ARG A 243
PHE A 180
 None
 1.10A 1s8fB-6b92A:
undetectable		 1s8fB-6b92A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 1.04A 1sduB-6b92A:
undetectable		 1sduB-6b92A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		6 / 12 PRO A  77
ILE A 109
GLY A 112
THR A 132
VAL A 134
ASN A 184
 SAH  A 305 ( 4.8A)
None
SAH  A 305 (-3.4A)
SAH  A 305 (-4.4A)
SAH  A 305 (-4.1A)
SAH  A 305 (-3.4A)
 0.74A 1sg9A-6b92A:
16.7		 1sg9A-6b92A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 PRO A  77
ILE A 109
GLY A 110
GLY A 112
VAL A 134
 SAH  A 305 ( 4.8A)
None
SAH  A 305 (-3.1A)
SAH  A 305 (-3.4A)
SAH  A 305 (-4.1A)
 0.40A 1sg9B-6b92A:
16.7		 1sg9B-6b92A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 PRO A  77
ILE A 109
GLY A 112
VAL A 134
ASN A 184
 SAH  A 305 ( 4.8A)
None
SAH  A 305 (-3.4A)
SAH  A 305 (-4.1A)
SAH  A 305 (-3.4A)
 0.76A 1sg9C-6b92A:
16.5		 1sg9C-6b92A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		4 / 6 LEU A 166
ALA A 169
LEU A 165
VAL A 158
 None
None
SAH  A 305 ( 4.6A)
None
 1.17A 1sn5A-6b92A:
undetectable		 1sn5A-6b92A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 10 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.99A 2aquA-6b92A:
undetectable		 2aquA-6b92A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.98A 2f80B-6b92A:
undetectable		 2f80B-6b92A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.93A 2pymA-6b92A:
undetectable		 2pymA-6b92A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.93A 2pymB-6b92A:
undetectable		 2pymB-6b92A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.93A 2pynA-6b92A:
undetectable		 2pynA-6b92A:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.92A 2pynB-6b92A:
undetectable		 2pynB-6b92A:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.90A 2q63B-6b92A:
undetectable		 2q63B-6b92A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.95A 2qakB-6b92A:
undetectable		 2qakB-6b92A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.95A 2qhcB-6b92A:
undetectable		 2qhcB-6b92A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.93A 3cywA-6b92A:
undetectable		 3cywA-6b92A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.90A 3cyxB-6b92A:
undetectable		 3cyxB-6b92A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.98A 3d1xB-6b92A:
undetectable		 3d1xB-6b92A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 11 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.84A 3em4A-6b92A:
undetectable		 3em4A-6b92A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 11 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.91A 3em4U-6b92A:
undetectable		 3em4U-6b92A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.95A 3lzsA-6b92A:
undetectable		 3lzsA-6b92A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.98A 3lzuA-6b92A:
undetectable		 3lzuA-6b92A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.97A 3ndtC-6b92A:
undetectable		 3ndtC-6b92A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 9 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.97A 3oxvA-6b92A:
undetectable		 3oxvA-6b92A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		4 / 7 LEU A 166
ALA A 169
LEU A 165
VAL A 158
 None
None
SAH  A 305 ( 4.6A)
None
 1.04A 3ozkB-6b92A:
undetectable		 3ozkB-6b92A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 1.00A 3pwmA-6b92A:
undetectable		 3pwmA-6b92A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 1.03A 3tkgB-6b92A:
undetectable		 3tkgB-6b92A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 1.03A 3tkgC-6b92A:
undetectable		 3tkgC-6b92A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.98A 3tkwA-6b92A:
undetectable		 3tkwA-6b92A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		3 / 3 ASP A 108
GLY A 112
TYR A 117
 SAH  A 305 ( 4.3A)
SAH  A 305 (-3.4A)
SAH  A 305 ( 4.8A)
 0.80A 3w9tG-6b92A:
undetectable		 3w9tG-6b92A:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		4 / 6 LEU A 166
ALA A 169
LEU A 165
VAL A 158
 None
None
SAH  A 305 ( 4.6A)
None
 0.98A 5a6iA-6b92A:
undetectable		 5a6iA-6b92A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		4 / 5 LEU A 166
ALA A 169
LEU A 165
VAL A 158
 None
None
SAH  A 305 ( 4.6A)
None
 1.15A 5cr1A-6b92A:
undetectable		 5cr1A-6b92A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		4 / 5 PHE A 180
GLY A 126
ASP A 179
ILE A  93
 None
 0.82A 5ik1A-6b92A:
undetectable		 5ik1A-6b92A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		4 / 4 VAL A  34
LEU A  23
ASN A  45
ASP A  48
 None
 1.36A 5vcyA-6b92A:
undetectable		 5vcyA-6b92A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 10 ILE A  68
LEU A  60
PHE A  64
LEU A 124
ALA A 122
 None
 1.19A 5y7pB-6b92A:
undetectable		 5y7pB-6b92A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 10 ILE A  68
LEU A  60
PHE A  64
LEU A 124
ALA A 122
 None
 1.19A 5y7pD-6b92A:
undetectable		 5y7pD-6b92A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 10 ILE A  68
LEU A  60
PHE A  64
LEU A 124
ALA A 122
 None
 1.16A 5y7pH-6b92A:
undetectable		 5y7pH-6b92A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 121
ALA A 122
GLY A 106
VAL A 157
ILE A 155
 None
 0.91A 6difB-6b92A:
undetectable		 6difB-6b92A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_0
(ADENOSYLHOMOCYSTEINA
SE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 10 GLY A 110
GLU A 133
VAL A 134
ASP A 135
CYH A 138
 SAH  A 305 (-3.1A)
SAH  A 305 (-2.7A)
SAH  A 305 (-4.1A)
None
SAH  A 305 (-3.6A)
 0.38A 6exiA-6b92A:
7.2		 6exiA-6b92A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_0
(ADENOSYLHOMOCYSTEINA
SE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 10 GLY A 110
GLY A 112
VAL A 134
ASP A 135
CYH A 138
 SAH  A 305 (-3.1A)
SAH  A 305 (-3.4A)
SAH  A 305 (-4.1A)
None
SAH  A 305 (-3.6A)
 1.15A 6exiA-6b92A:
7.2		 6exiA-6b92A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_1
(ADENOSYLHOMOCYSTEINA
SE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 10 GLY A 110
GLU A 133
VAL A 134
ASP A 135
CYH A 138
 SAH  A 305 (-3.1A)
SAH  A 305 (-2.7A)
SAH  A 305 (-4.1A)
None
SAH  A 305 (-3.6A)
 0.37A 6exiB-6b92A:
7.3		 6exiB-6b92A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_1
(ADENOSYLHOMOCYSTEINA
SE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 10 GLY A 110
GLY A 112
VAL A 134
ASP A 135
CYH A 138
 SAH  A 305 (-3.1A)
SAH  A 305 (-3.4A)
SAH  A 305 (-4.1A)
None
SAH  A 305 (-3.6A)
 1.11A 6exiB-6b92A:
7.3		 6exiB-6b92A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 110
GLU A 133
VAL A 134
ASP A 135
CYH A 138
 SAH  A 305 (-3.1A)
SAH  A 305 (-2.7A)
SAH  A 305 (-4.1A)
None
SAH  A 305 (-3.6A)
 0.37A 6exiC-6b92A:
7.0
6exiD-6b92A:
4.1		 6exiC-6b92A:
20.73
6exiD-6b92A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 110
GLY A 112
VAL A 134
ASP A 135
CYH A 138
 SAH  A 305 (-3.1A)
SAH  A 305 (-3.4A)
SAH  A 305 (-4.1A)
None
SAH  A 305 (-3.6A)
 1.16A 6exiC-6b92A:
7.0
6exiD-6b92A:
4.1		 6exiC-6b92A:
20.73
6exiD-6b92A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND503_0
(ADENOSYLHOMOCYSTEINA
SE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 110
GLU A 133
VAL A 134
ASP A 135
CYH A 138
 SAH  A 305 (-3.1A)
SAH  A 305 (-2.7A)
SAH  A 305 (-4.1A)
None
SAH  A 305 (-3.6A)
 0.37A 6exiC-6b92A:
6.9
6exiD-6b92A:
4.1		 6exiC-6b92A:
20.73
6exiD-6b92A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND503_0
(ADENOSYLHOMOCYSTEINA
SE)		 6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLY A 110
GLY A 112
VAL A 134
ASP A 135
CYH A 138
 SAH  A 305 (-3.1A)
SAH  A 305 (-3.4A)
SAH  A 305 (-4.1A)
None
SAH  A 305 (-3.6A)
 1.15A 6exiC-6b92A:
6.9
6exiD-6b92A:
4.1		 6exiC-6b92A:
20.73
6exiD-6b92A:
20.73