SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDS_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 6b9g ATLASTIN-1
(Homo
sapiens) 		5 / 12 ILE B 129
LEU B  53
SER B 167
ILE B 170
LEU B 325
 None
 1.04A 1ddsB-6b9gB:
undetectable		 1ddsB-6b9gB:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 6b9g ATLASTIN-1
(Homo
sapiens) 		4 / 6 PHE B 293
PHE B  82
LEU B 286
VAL B 100
 None
GDP  B 401 (-4.3A)
None
None
 0.61A 1hk1A-6b9gB:
undetectable		 1hk1A-6b9gB:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 6b9g ATLASTIN-1
(Homo
sapiens) 		4 / 7 PHE B 293
PHE B  82
LEU B 286
VAL B 100
 None
GDP  B 401 (-4.3A)
None
None
 0.57A 1hk3A-6b9gB:
undetectable		 1hk3A-6b9gB:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 6b9g ATLASTIN-1
(Homo
sapiens) 		3 / 3 PHE B 235
VAL B 216
TRP B 219
 None
 0.81A 2cc8A-6b9gB:
undetectable		 2cc8A-6b9gB:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 6b9g ATLASTIN-1
(Homo
sapiens) 		3 / 3 PHE B 235
VAL B 216
TRP B 219
 None
 0.80A 2ccbA-6b9gB:
undetectable		 2ccbA-6b9gB:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 6b9g ATLASTIN-1
(Homo
sapiens) 		4 / 5 SER B 155
THR B 150
SER B 153
ASP B 152
 None
 1.35A 2hdnB-6b9gB:
5.1
2hdnC-6b9gB:
undetectable
2hdnD-6b9gB:
3.2		 2hdnB-6b9gB:
14.89
2hdnC-6b9gB:
19.23
2hdnD-6b9gB:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 6b9g ATLASTIN-1
(Homo
sapiens) 		3 / 3 PHE B 235
VAL B 216
TRP B 219
 None
 0.80A 2vx9A-6b9gB:
undetectable		 2vx9A-6b9gB:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6b9g ATLASTIN-1
(Homo
sapiens) 		4 / 5 ARG B 113
PHE B  86
LEU B 107
PHE B 282
 None
 1.36A 2y69P-6b9gB:
undetectable
2y69W-6b9gB:
undetectable		 2y69P-6b9gB:
undetectable
2y69W-6b9gB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 6b9g ATLASTIN-1
(Homo
sapiens) 		5 / 12 TYR B 336
TYR B 196
PHE B 151
ILE B 123
ILE B 170
 None
 1.30A 3ndiA-6b9gB:
undetectable		 3ndiA-6b9gB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 6b9g ATLASTIN-1
(Homo
sapiens) 		3 / 3 SER B  81
MET B  84
ASP B 218
 GDP  B 401 ( 2.5A)
None
GDP  B 401 (-2.7A)
 0.82A 4mm4B-6b9gB:
undetectable		 4mm4B-6b9gB:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 6b9g ATLASTIN-1
(Homo
sapiens) 		4 / 8 ASN B 177
MET B  87
LEU B 297
ILE B 213
 None
 1.00A 4ok1A-6b9gB:
undetectable		 4ok1A-6b9gB:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 6b9g ATLASTIN-1
(Homo
sapiens) 		5 / 11 ILE B 129
LEU B  53
SER B 167
ILE B 170
LEU B 325
 None
 1.15A 4qleB-6b9gB:
undetectable		 4qleB-6b9gB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 6b9g ATLASTIN-1
(Homo
sapiens) 		3 / 3 TRP B 303
ILE B 173
SER B 211
 None
 0.59A 5gqbA-6b9gB:
undetectable		 5gqbA-6b9gB:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 6b9g ATLASTIN-1
(Homo
sapiens) 		5 / 12 ASP B 218
THR B 150
GLY B  74
THR B 147
SER B 179
 GDP  B 401 (-2.7A)
None
None
None
None
 1.29A 5hfjC-6b9gB:
undetectable		 5hfjC-6b9gB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 6b9g ATLASTIN-1
(Homo
sapiens) 		5 / 12 ILE B 129
LEU B  53
SER B 167
ILE B 170
LEU B 325
 None
 1.06A 5hi6A-6b9gB:
undetectable		 5hi6A-6b9gB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 6b9g ATLASTIN-1
(Homo
sapiens) 		5 / 12 LEU B 300
LEU B 269
SER B 167
LEU B 304
LEU B 144
 None
 1.08A 6ew0B-6b9gB:
undetectable		 6ew0B-6b9gB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 6b9g ATLASTIN-1
(Homo
sapiens) 		5 / 12 LEU B 300
LEU B 269
SER B 167
LEU B 304
LEU B 144
 None
 1.07A 6ew0D-6b9gB:
undetectable		 6ew0D-6b9gB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 6b9g ATLASTIN-1
(Homo
sapiens) 		5 / 12 LEU B 300
LEU B 269
SER B 167
LEU B 304
LEU B 144
 None
 1.08A 6ew0H-6b9gB:
undetectable		 6ew0H-6b9gB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 6b9g ATLASTIN-1
(Homo
sapiens) 		5 / 12 LEU B 300
LEU B 269
SER B 167
LEU B 304
LEU B 144
 None
 1.08A 6ew0I-6b9gB:
undetectable		 6ew0I-6b9gB:
19.54