SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 12 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.83A 1c6yB-6b9hA:
undetectable		 1c6yB-6b9hA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 9 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.81A 1hpvA-6b9hA:
undetectable		 1hpvA-6b9hA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 11 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.77A 1n49B-6b9hA:
undetectable		 1n49B-6b9hA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 11 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.76A 1n49C-6b9hA:
undetectable		 1n49C-6b9hA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 12 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.86A 1sdtB-6b9hA:
undetectable		 1sdtB-6b9hA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 11 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.87A 1sdvB-6b9hA:
undetectable		 1sdvB-6b9hA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		4 / 6 MET A  41
VAL A  44
LEU A  45
PHE A  53
 None
 1.19A 1x8vA-6b9hA:
undetectable		 1x8vA-6b9hA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 12 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.78A 2o4sA-6b9hA:
undetectable		 2o4sA-6b9hA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		4 / 5 LEU A 119
LEU A 115
LEU A 105
MET A  41
 None
 1.01A 2oaxF-6b9hA:
undetectable		 2oaxF-6b9hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 12 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.76A 2pynB-6b9hA:
undetectable		 2pynB-6b9hA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 12 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.75A 2q64A-6b9hA:
undetectable		 2q64A-6b9hA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 12 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.74A 2qakB-6b9hA:
undetectable		 2qakB-6b9hA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 12 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.81A 3jvyB-6b9hA:
undetectable		 3jvyB-6b9hA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		5 / 11 GLY A 124
VAL A  44
ILE A  20
ILE A 139
ILE A  48
 None
 0.79A 4njvC-6b9hA:
undetectable		 4njvC-6b9hA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		4 / 6 LEU A 123
MET A 142
MET A  41
VAL A  25
 None
 1.14A 4okbA-6b9hA:
undetectable		 4okbA-6b9hA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 6b9h PROTEIN HOOK HOMOLOG
3
(Homo
sapiens) 		4 / 4 ILE A  79
ASN A  75
ILE A  73
VAL A 103
 None
 1.19A 4uy87-6b9hA:
undetectable		 4uy87-6b9hA:
undetectable