SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 6b9m E3 UBIQUITIN-PROTEIN
LIGASE UHRF1
(Danio
rerio;
Homo
sapiens) 		5 / 12 ARG D 649
GLU A 155
SER D 651
TYR A 180
VAL A 143
 None
 1.23A 1x70A-6b9mD:
undetectable		 1x70A-6b9mD:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 6b9m E3 UBIQUITIN-PROTEIN
LIGASE UHRF1
(Danio
rerio;
Homo
sapiens) 		5 / 12 ARG D 649
GLU A 155
SER D 651
TYR A 180
VAL A 143
 None
 1.24A 1x70B-6b9mD:
undetectable		 1x70B-6b9mD:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 6b9m E3 UBIQUITIN-PROTEIN
LIGASE UHRF1
(Danio
rerio) 		4 / 7 TYR A 137
TRP A 153
GLU A 275
PRO A 198
 None
 0.99A 3hs4A-6b9mA:
undetectable		 3hs4A-6b9mA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 6b9m E3 UBIQUITIN-PROTEIN
LIGASE UHRF1
(Danio
rerio) 		4 / 6 GLU A 173
GLY A 170
GLY A 169
ASP A 168
 None
 0.84A 5a06D-6b9mA:
undetectable		 5a06D-6b9mA:
undetectable