SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b9r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		4 / 4 SER A 395
LEU A 204
TYR A 366
GLY A 393
 None
 1.48A 1liiA-6b9rA:
undetectable		 1liiA-6b9rA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		4 / 5 ASN A  31
ALA A  34
ASP A  32
GLU A  36
 None
 1.38A 1lqtA-6b9rA:
undetectable
1lqtB-6b9rA:
undetectable		 1lqtA-6b9rA:
undetectable
1lqtB-6b9rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		4 / 5 ASN A  31
ALA A  34
ASP A  32
GLU A  36
 None
 1.36A 1lquA-6b9rA:
undetectable
1lquB-6b9rA:
undetectable		 1lquA-6b9rA:
undetectable
1lquB-6b9rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		4 / 7 GLY A 335
HIS A 339
TYR A 152
PRO A 186
 None
 1.12A 1th6A-6b9rA:
undetectable		 1th6A-6b9rA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		4 / 7 GLY A 335
HIS A 339
TYR A 152
PRO A 186
 None
 1.11A 2armA-6b9rA:
undetectable		 2armA-6b9rA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		4 / 8 PHE A 330
LEU A 358
LEU A 367
LEU A 414
 None
 0.87A 2bfpA-6b9rA:
undetectable		 2bfpA-6b9rA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		4 / 8 PHE A 330
LEU A 358
LEU A 367
LEU A 414
 None
 1.02A 2bfpD-6b9rA:
undetectable		 2bfpD-6b9rA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		5 / 12 ALA A 205
SER A  94
SER A  97
TYR A 366
THR A 155
 2HE  A 502 ( 4.3A)
None
None
None
None
 1.16A 2bl9A-6b9rA:
undetectable		 2bl9A-6b9rA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_A_FCNA1199_1
(EPOXIDASE)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		6 / 9 ARG A 103
TYR A 111
ASN A 146
HIS A 149
HIS A 190
ALA A 205
 2HE  A 502 (-3.1A)
2HE  A 502 (-4.4A)
2HE  A 502 (-3.7A)
FE  A 501 ( 3.4A)
FE  A 501 ( 3.3A)
2HE  A 502 ( 4.3A)
 0.47A 2bnnA-6b9rA:
14.0
2bnnB-6b9rA:
13.4		 2bnnA-6b9rA:
17.91
2bnnB-6b9rA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		5 / 8 TYR A 111
ASN A 146
HIS A 149
HIS A 190
ALA A 205
 2HE  A 502 (-4.4A)
2HE  A 502 (-3.7A)
FE  A 501 ( 3.4A)
FE  A 501 ( 3.3A)
2HE  A 502 ( 4.3A)
 0.51A 2bnnA-6b9rA:
14.0
2bnnB-6b9rA:
13.4		 2bnnA-6b9rA:
17.91
2bnnB-6b9rA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_D_C2FD1200_0
(GLYCINE
N-METHYLTRANSFERASE)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		5 / 12 LEU A 415
TYR A 366
LEU A 204
THR A 155
THR A 207
 None
 1.47A 3thrA-6b9rA:
undetectable
3thrB-6b9rA:
0.8
3thrC-6b9rA:
1.1
3thrD-6b9rA:
1.5		 3thrA-6b9rA:
undetectable
3thrB-6b9rA:
undetectable
3thrC-6b9rA:
undetectable
3thrD-6b9rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		4 / 8 PHE A 187
HIS A 190
GLY A 148
GLY A 209
 None
FE  A 501 ( 3.3A)
None
None
 0.73A 3v3nB-6b9rA:
undetectable		 3v3nB-6b9rA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		4 / 8 PHE A 187
HIS A 190
GLY A 148
GLY A 209
 None
FE  A 501 ( 3.3A)
None
None
 0.73A 3v3nC-6b9rA:
undetectable		 3v3nC-6b9rA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		3 / 3 TYR A 362
HIS A 341
ARG A 428
 None
 1.13A 4e7bC-6b9rA:
undetectable		 4e7bC-6b9rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		3 / 3 GLU A  36
ASP A  32
ASP A  38
 None
 0.78A 4gc9A-6b9rA:
undetectable		 4gc9A-6b9rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		4 / 4 ALA A  11
ALA A  14
ALA A  15
ALA A  18
 None
 0.11A 4oaeA-6b9rA:
undetectable		 4oaeA-6b9rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		3 / 3 ASP A  38
LEU A 448
ARG A  22
 None
 0.94A 5e8qA-6b9rA:
undetectable		 5e8qA-6b9rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE
(Streptomyces
albus) 		3 / 3 GLU A  36
LEU A  39
ARG A  63
 None
 0.80A 6d8fA-6b9rA:
undetectable		 6d8fA-6b9rA:
undetectable